The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle
Ringkasan
TLDRThe video provides an in-depth analysis of the importance of protein beyond its muscle-building role, emphasizing its impact on metabolism, disease prevention, and aging. It challenges the adequacy of the recommended dietary allowance (RDA) and suggests higher protein intakes, particularly for older adults and those engaging in resistance training, are beneficial. The discussion extends to the myths and realities about the risks of high protein diets, especially concerning kidney health and potential links to cancer. It also addresses the context of exercise, the differences between animal and plant proteins, and the role of leucine in muscle synthesis. Practical strategies are suggested for vegetarians and vegans to meet protein needs, alongside a review of protein timing and intake recommendations tailored to individual goals. The interplay of protein intake, lifestyle, and longevity is explored, highlighting the transformative role of physical activity in mitigating any potential adverse effects of high protein consumption.
Takeaways
- 💪 Protein is essential beyond muscle building, impacting metabolism and disease prevention.
- 🥩 High protein intake, especially from meat, raises both health benefits and risks.
- 🏋️♂️ Resistance training paired with protein enhances muscle growth.
- 👴 Aging affects muscle synthesis needing higher protein intake.
- 🥬 Plant-based proteins can meet needs with diversified sources.
- ⚖️ Optimal protein intake varies by individual goals.
- ✨ Anabolic window for protein intake is broader than believed.
- 🧠 IGF-1's role in muscle and brain health requires exercise context.
- 🌱 Animal proteins have a higher impact on muscle synthesis.
- 🔥 High protein diets don't harm healthy kidneys.
Garis waktu
- 00:00:00 - 00:05:00
Today's episode focuses on the essential role of protein in our bodies beyond just muscle building. Protein impacts metabolism, insulin sensitivity, and prevents diseases like type 2 diabetes and sarcopenia. We examine how much is needed for health, the benefits of higher intake, the impact of protein on muscle maintenance and aging, and how lifestyle influences protein requirements.
- 00:05:00 - 00:10:00
Muscle mass is a significant indicator of aging, and its decline begins post-50s. Exercise, especially resistance training, and protein are crucial for maintaining muscle health. Studies highlight the benefits of increased protein intake for those engaging in resistance training. Protein supports metabolism, reduces frailty, and lowers the risk of age-related issues like fractures.
- 00:10:00 - 00:15:00
Anabolic resistance increases with age, reducing muscle responsiveness to protein intake. Older adults need more protein to stimulate muscle synthesis, but exercise can mitigate anabolic resistance. Staying active enhances muscle sensitivity to protein, underlining the importance of combining physical activity with adequate protein intake to maintain muscle health in older age.
- 00:15:00 - 00:20:00
The RDA for protein is often considered too low for muscle maintenance. Higher intakes of 1.2 to 1.6 g/kg are recommended for preserving lean mass and reducing frailty in older adults. Those in resistance training can benefit from higher amounts. During body recomposition or weight loss, increased protein offers satiety and protects against loss of muscle mass while aiding metabolism.
- 00:20:00 - 00:25:00
Concerns over high protein diets affecting kidney health are largely unfounded in people without kidney issues. Higher protein intake can enhance metabolic rates slightly. The myth that protein needs to be consumed within a narrow anabolic window post-exercise is dispelled, as muscle synthesis is elevated for much longer post-exercise. Consuming protein before sleep can aid recovery.
- 00:25:00 - 00:30:00
Animal proteins are generally better for muscle synthesis due to their amino acid profile, especially leucine content. Plant-based proteins can be sufficient if intake is higher and diversified. Protein supplements like whey are effective due to high leucine content. Despite some aging-related concerns about high protein intake, physical activity offsets potential negative effects like increased IGF-1.
- 00:30:00 - 00:40:09
Exercise plays a key role in utilizing protein efficiently, directing growth factors beneficially and altering how IGF-1 impacts the body, mitigating cancer risks. Active individuals, including athletes, benefit from high protein for muscle and cognitive health without the risks purported for sedentary lifestyles. The discussion concludes with key takeaways on protein intake and strategies.
Peta Pikiran
Video Tanya Jawab
What role does protein play besides building muscle?
Protein is crucial for metabolism, insulin sensitivity, and disease prevention.
Is high protein intake from meat risky?
High protein intake, especially from meat, has both potential health benefits and risks.
Why is muscle building important as we age?
Muscle building combats frailty and sarcopenia, improving quality of life in older age.
What is the optimal protein intake for muscle growth?
1.2 to 1.6 grams per kilogram, and up to 2 grams for body recomposition, is considered beneficial.
How do plant proteins compare to animal proteins?
Animal proteins are superior in muscle synthesis; however, plant proteins can suffice with diversified sources.
Does protein timing matter for muscle growth?
While timing can enhance benefits, overall daily intake is more critical for muscle gains.
Does high protein harm kidney health?
High protein diets do not harm kidney health in people without pre-existing conditions.
How does protein affect aging and cancer risk?
High protein intake may influence aging and cancer risk, context matters, particularly with physical activity.
Why is leucine crucial in protein intake?
Leucine triggers muscle synthesis, making it vital for effective protein consumption.
Are athletes' high protein diets detrimental?
Athletes typically benefit from high protein diets, showing longer lifespans and better health. Physical activity modifies how protein affects the body.
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- 00:00:00welcome to today's deep exploration into
- 00:00:02one of nutrition's most critical and
- 00:00:04debated topics protein Beyond its
- 00:00:07well-known role as the building block of
- 00:00:09muscle protein is fundamental to our
- 00:00:11metabolism insulin sensitivity and the
- 00:00:14prevention of diseases such as type two
- 00:00:16diabetes and sarcopenia but how much
- 00:00:19dietary protein do we really need and
- 00:00:21could too much protein especially from
- 00:00:23meat actually be harmful today we'll
- 00:00:27discuss why maintaining and even
- 00:00:29building muscle is critical for everyone
- 00:00:32not just athletes you'll discover how
- 00:00:34protein intake coupled with resistance
- 00:00:36training drives muscle repair and growth
- 00:00:39enhancing athletic performance improving
- 00:00:41metabolic health and promoting longevity
- 00:00:44by acting as a defense against age
- 00:00:46related Frailty you'll learn about
- 00:00:48optimal protein amounts based on age
- 00:00:50activity level and goals whether you
- 00:00:52want to actively gain muscle maintain it
- 00:00:55or just improve body composition we will
- 00:00:58critically examine current protein
- 00:01:00recommendations challenging the adequacy
- 00:01:02of the RDA of 0.8 G per kilogram body
- 00:01:05weight drawing on the latest research we
- 00:01:08discuss why higher intakes ranging from
- 00:01:111.2 to 1.6 grams per kilogram are more
- 00:01:14beneficial for General Health and why up
- 00:01:16to two grams or higher may be best for
- 00:01:19body recomposition addressing the
- 00:01:21contentious links between high protein
- 00:01:23diets and health risks we will analyze
- 00:01:25evidence surrounding proteins
- 00:01:27association with cancer heart disease
- 00:01:29and kidney function we'll explore how
- 00:01:32lifestyle factors particularly physical
- 00:01:34activity profoundly influence these
- 00:01:36risks specifically we'll uncover how
- 00:01:39exercise modulates growth factors like
- 00:01:41igf-1 diverting them towards muscle and
- 00:01:44brain tissue where they support repair
- 00:01:46and growth while potentially mitigating
- 00:01:48their procancer effects in other tissues
- 00:01:50we dissect the differences between
- 00:01:52animal and plant proteins in stimulating
- 00:01:54muscle protein synthesis we'll provide
- 00:01:56practical strategies for vegetarians and
- 00:01:59vegans to meet their protein needs
- 00:02:00effectively through increased total
- 00:02:02intake Diversified sources and the use
- 00:02:05of plant-based protein concentrates
- 00:02:08we'll also dispel myths around protein
- 00:02:10intake timing you'll learn how
- 00:02:12Distributing protein evenly across males
- 00:02:14can maximize muscle protein synthesis
- 00:02:16and why the so-called post exercise
- 00:02:18anabolic window may not be as narrow as
- 00:02:21once thought additionally we highlight
- 00:02:24the pivotal role of the amino acid
- 00:02:26Lucine in activating muscle building
- 00:02:28Pathways and how this impacts protein
- 00:02:30quality considerations by the end of
- 00:02:33this episode you'll be equipped with all
- 00:02:35of the evidence-based insights you need
- 00:02:37to better navigate common misconceptions
- 00:02:39and ultimately harness protein for
- 00:02:41muscle maintenance performance and a
- 00:02:43Frailty free future so let's get into it
- 00:02:47how much muscle we have tells us more
- 00:02:49about how we are aging than body weight
- 00:02:51or BMI ever could here's a startling
- 00:02:53fact after the age of 50 the average
- 00:02:56person loses about 1% of their muscle
- 00:02:59mass every single year and it's not just
- 00:03:02muscle mass strength plummets even
- 00:03:04faster dropping around 3% annually by
- 00:03:08the time you reach 75 if you're not
- 00:03:10engaging in regular strength training
- 00:03:12you could be losing up to 4% of your
- 00:03:14strength every year so what can we do
- 00:03:17about this exercise both before you need
- 00:03:20it building muscle Reserve but also in
- 00:03:23old age to slow and reverse the decline
- 00:03:26while resistance training is the most
- 00:03:27important factor for building and
- 00:03:29maintaining muscle mass and strength
- 00:03:31protein intake plays an important role
- 00:03:33too a metaanalysis from Dr Stuart
- 00:03:35Phillips and colleagues highlights the
- 00:03:37importance of protein intake by showing
- 00:03:40that people who engage in resistance
- 00:03:41training and supplemented with
- 00:03:43additional protein taking their total
- 00:03:46daily protein intake up to 1.6 gram per
- 00:03:49kilogram body weight increase their
- 00:03:51muscle mass by 27% and their strength by
- 00:03:5410% more than those who did resistance
- 00:03:57training without additional protein
- 00:03:59supplementation
- 00:04:00so these people were getting around 1.2
- 00:04:02g of protein per kilogram body weight so
- 00:04:05dialing in that protein intake matters
- 00:04:06for both muscle mass and strength when
- 00:04:08combined with resistance training
- 00:04:10skeletal muscle makes up around 30 to
- 00:04:1240% of our lean body mass more muscle
- 00:04:16doesn't just mean more strength it means
- 00:04:18better metabolism enhanced insulin
- 00:04:20sensitivity and a pretty good defense
- 00:04:23against type two diabetes it also
- 00:04:25dramatically decreases Frailty and the
- 00:04:27risk for sarcopenia one of the the main
- 00:04:30risk factors for Falls and fractures in
- 00:04:32older adults research has shown that
- 00:04:35individuals who suffer from a fragility
- 00:04:37fracture are twice as likely to die
- 00:04:40compared to those without such fractures
- 00:04:42and between 22 to 58% of people with a
- 00:04:46hip fracture pass away within just 12
- 00:04:49months after the injury in old age
- 00:04:52falling and breaking a hip can literally
- 00:04:55be a death sentence a better body
- 00:04:57composition dramatically improves
- 00:04:59quality of life and reduces disability
- 00:05:02risk having a higher muscle mass can
- 00:05:04decrease the risk of early death by 30%
- 00:05:07whereas having a high fat Mass can
- 00:05:10increase that risk by
- 00:05:1256% so what explains our greater
- 00:05:15susceptibility to lose muscle mass as we
- 00:05:17get older there are a few factors that
- 00:05:19play a role in this but a big player
- 00:05:21here is a phenomenon called anabolic
- 00:05:24resistance so as we age our muscles
- 00:05:27become less responsive to amino acids
- 00:05:29meaning they don't trigger muscle
- 00:05:31protein synthesis in response to protein
- 00:05:33intake as effectively so for older
- 00:05:36individuals the same amount of protein
- 00:05:38results in a smaller increase in muscle
- 00:05:41protein synthesis compared to younger
- 00:05:43people some Studies have shown that an
- 00:05:45older person requires almost twice as
- 00:05:46much protein for the same response for
- 00:05:49example around 0.24 gram of protein per
- 00:05:52kilogram body weight or 0.1 G per pound
- 00:05:55that's 20 gram of protein for about an
- 00:05:5780 kgam man maximally stimulates muscle
- 00:06:01protein synthesis in someone young but
- 00:06:03this dose is higher for older adults who
- 00:06:05need about 0.4 gram of protein per
- 00:06:07kilogram or 0.18 gam per pound of
- 00:06:10protein per dose an older adult man
- 00:06:13weighing about 80 kilg would need about
- 00:06:1532 grams of protein to maximally
- 00:06:17stimulate muscle protein synthesis by
- 00:06:19the way for anyone taking notes this
- 00:06:21suggests that the optimal amount of
- 00:06:23protein per dose is between 20 and as
- 00:06:26high as 35 gram of protein depending on
- 00:06:28your personal level of anabolic
- 00:06:30resistance so this means a few things
- 00:06:33the first is that if you're older you
- 00:06:35need a higher total daily protein intake
- 00:06:38to maintain or increase muscle mass it
- 00:06:41also means that you need a higher dose
- 00:06:42of protein at each meal to stimulate
- 00:06:45muscle protein synthesis but anabolic
- 00:06:47resistance is not inevitable or only due
- 00:06:49to aging as some might suggest in fact
- 00:06:52physical inactivity may actually be the
- 00:06:54biggest contributor reducing physical
- 00:06:56activity worsens anabolic resistance for
- 00:06:59example taking fewer steps for just 2
- 00:07:01weeks causes anabolic resistance in
- 00:07:03older adults and reduces their insulin
- 00:07:06sensitivity imagine what decades of
- 00:07:08inactivity can do that's the bad news
- 00:07:11but the good news is that exercise makes
- 00:07:13muscle more sensitive to protein and
- 00:07:15essentially negates anabolic resistance
- 00:07:18when older adults exercise before
- 00:07:20protein intake their muscle anabolic
- 00:07:22response is identical to that of a
- 00:07:25younger adult so how do I interpret this
- 00:07:28active old older adults probably don't
- 00:07:31experience as much anabolic resistance
- 00:07:33as inactive people and therefore it
- 00:07:35might not be such an issue for people
- 00:07:37that are Physically Active the most
- 00:07:39effective way to combat anabolic
- 00:07:41resistance as we age is through regular
- 00:07:43physical activity combined with a higher
- 00:07:45daily protein intake ideally around 1.6
- 00:07:48gram per kilogram body weight we do not
- 00:07:51have to be frail in old age we can build
- 00:07:54muscle into our 40s 50s 60s and even our
- 00:07:5770s and Beyond and we can def Ely
- 00:07:59increased muscle strength and power
- 00:08:01output at this age in one study that
- 00:08:03recruited adults aged 90 years and older
- 00:08:068 weeks of high-intensity strength
- 00:08:08training produced a 174% increase in
- 00:08:11muscle strength muscle strength and size
- 00:08:14increased even in the ninth decade of
- 00:08:16Life an age when most people wouldn't
- 00:08:18even think twice about touching a weight
- 00:08:20so let's talk about the optimal protein
- 00:08:22intake the optimal amount of protein
- 00:08:25will not be the same for everyone some
- 00:08:27people want to build muscle mass some
- 00:08:28people want to Main ttain it and others
- 00:08:30want to improve their body composition
- 00:08:32by building muscle and losing fat each
- 00:08:34of these goals requires a more tailored
- 00:08:37approach the first thing to knowe is
- 00:08:38that it's generally agreed upon that
- 00:08:40protein needs should be calculated based
- 00:08:42on a lean body mass or an adjusted body
- 00:08:45weight reflecting a healthy body fat
- 00:08:47percentage so for example 12 to 15% for
- 00:08:50men and around 20% for women this
- 00:08:53prevents unrealistic targets especially
- 00:08:55for those who are overweight or obese so
- 00:08:58when I refer to protein intake in grams
- 00:09:01per kilogram of body weight per day what
- 00:09:03I'm ideally referring to is your ideal
- 00:09:06or goal body weight let's address one
- 00:09:08thing up front the recommended dietary
- 00:09:11allowance or the RDA for protein of 0.8
- 00:09:14gr per kilogram per day is thought by
- 00:09:17many to be too low this is because the
- 00:09:20RDA was derived from nitrogen balance
- 00:09:22studies which have limitations due to
- 00:09:25incomplete collection and inaccurate
- 00:09:27estimates of amino acid loss
- 00:09:30the optimal range for daily protein
- 00:09:32intake is closer to 1.2 to 1.6 G per
- 00:09:36kilogram body weight per day or roughly
- 00:09:390.54 to 0.72 G per pound this is based
- 00:09:44on alternative methods like stable
- 00:09:46isotope studies which consistently show
- 00:09:48that higher intakes are necessary to
- 00:09:51maintain a positive protein balance far
- 00:09:54above the 0.8 G per kilogram often cited
- 00:09:57so aiming for at least 1.2 gr and up to
- 00:10:001.6 G is what we're talking about for
- 00:10:02optimal protein intake there's good
- 00:10:05evidence to suggest this for example
- 00:10:07older adults consuming at least 1.2
- 00:10:09grams of protein per kilogram body
- 00:10:11weight per day prevented age related
- 00:10:14losses in lean mass when compared to
- 00:10:15consuming the RDA of 0.8 gr per kilogram
- 00:10:19body weight older women were also 30%
- 00:10:22less likely to experience Frailty when
- 00:10:25consuming protein above the RDA so what
- 00:10:28is the optimal protein intake for
- 00:10:30building muscle while resistance
- 00:10:32training for people engaged in
- 00:10:34resistance training a protein intake of
- 00:10:371.6 gram per kilogram body weight per
- 00:10:39day has been shown to maximize gains in
- 00:10:42lean body mass with a 27% increase in
- 00:10:45muscle mass over even a 1.2 gam per
- 00:10:49kilogram intake that's a lot and it
- 00:10:51really just serves to really underscore
- 00:10:54how low the RDA really is when you're
- 00:10:57talking about 0.8 G per kilogram body
- 00:11:00weight by the way for an excellent
- 00:11:02discussion of the protein RDA and much
- 00:11:04more see my interview with Dr Stuart
- 00:11:07Phillips in episode 76 of the Fami
- 00:11:09Fitness podcast there are special
- 00:11:11circumstances where even a higher
- 00:11:13protein intake might offer some marginal
- 00:11:15benefit the first example is people
- 00:11:17undergoing body recomposition where they
- 00:11:19are in an energy deficit to lose fat
- 00:11:21Mass while preserving or even increasing
- 00:11:24muscle mass so let's talk a little bit
- 00:11:26more about body recomposition and weight
- 00:11:28loss a higher protein intake tends to
- 00:11:30improve satiety it helps you feel Fuller
- 00:11:32for longer and may help prevent
- 00:11:34overeating for people who want to lose
- 00:11:36weight this is a major benefit eating
- 00:11:39more protein is also essential during
- 00:11:40weight loss to prevent the loss of lean
- 00:11:42body mass when you eat a higher protein
- 00:11:45calorie restricted diet more weight loss
- 00:11:48comes from fat mass than muscle mass but
- 00:11:50remember resistance training is also
- 00:11:53important to prevent the loss of lean
- 00:11:54mass high protein diets may also cause a
- 00:11:56slight increase in the metabolic rate
- 00:11:58due to the thermic effective food
- 00:12:00helping you burn a few more calories
- 00:12:02throughout the day the second example
- 00:12:03where a higher protein intake above 1.6
- 00:12:06G per kilogram may be beneficial is with
- 00:12:08professional athletes where extremely
- 00:12:10marginal improvements in muscle protein
- 00:12:12synthesis gives them an edge on
- 00:12:14competition so in this scenario this is
- 00:12:17where up to 2.2 grams of protein per
- 00:12:19kilogram per day or one gram per pound
- 00:12:22May provide marginal benefits despite
- 00:12:25common misconceptions a very high
- 00:12:27protein intake is not harmful to Kidney
- 00:12:29Health in people without pre-existing
- 00:12:31kidney conditions research consistently
- 00:12:34shows that high protein diets are safe
- 00:12:36for most people and any concerns over
- 00:12:39kidney damage are largely unfounded so
- 00:12:42let's talk about this myth early
- 00:12:44interpretations of certain studies
- 00:12:45suggested that excessive protein intake
- 00:12:47might overwork the kidneys while protein
- 00:12:50restriction can slow the progression of
- 00:12:52kidney disease in some individuals we
- 00:12:54now know this does not imply that a
- 00:12:56healthy people should limit their
- 00:12:58protein consumption higher protein diets
- 00:13:00do induce changes in kidney function but
- 00:13:02they do not overburden the kidneys The
- 00:13:04observed increase in markers in kidney
- 00:13:06function is a normal adaptive response
- 00:13:09to eliminate Ura and other waste
- 00:13:11products generated during protein
- 00:13:12metabolism this is entirely normal for
- 00:13:15individuals with healthy renal function
- 00:13:17so current evidence does not support an
- 00:13:19association between higher protein
- 00:13:21intake and kidney disease among healthy
- 00:13:24adults or those at risk such as
- 00:13:26individuals with obesity hypertension or
- 00:13:28even diabetes I abetes moreover research
- 00:13:31and athletes has shown that consuming
- 00:13:32protein intakes as high as 3.2 to 4.5
- 00:13:36Gams per kilogram of body weight per day
- 00:13:39for up to one year does not cause any
- 00:13:42adverse changes in kidney function and
- 00:13:44is considered safe this intake is four
- 00:13:47to six times higher than the RDA for
- 00:13:49protein and emerging research even
- 00:13:52suggests that higher protein intake may
- 00:13:54actually be beneficial for people with
- 00:13:56chronic kidney disease some Studies have
- 00:13:58found that consuming protein at levels
- 00:14:00above the RDA is associated with reduced
- 00:14:03mortality risk in this population
- 00:14:05challenging the traditional approach of
- 00:14:07protein restriction the bottom line we
- 00:14:10can finally put to rest the myth that
- 00:14:11high protein diets harm healthy kidneys
- 00:14:14it's time to tackle another important
- 00:14:16aspect of protein intake and that's how
- 00:14:18often and when we should consume it
- 00:14:21we'll tackle two key points first how we
- 00:14:24consume our daily protein intake whether
- 00:14:26we should spread it evenly across 3 to
- 00:14:28four meals or load it up into one or two
- 00:14:30meals second and related does protein
- 00:14:34have to be consumed within a critical
- 00:14:36anabolic window or timed with our
- 00:14:38workouts in short the answer to both of
- 00:14:40these is that factors are less important
- 00:14:42overall than you might expect emerging
- 00:14:44evidence reveals that the body can
- 00:14:46effectively utilize even very large
- 00:14:48protein doses this challenges the notion
- 00:14:51that protein must be meticulously spread
- 00:14:53over multiple meals to maximize muscle
- 00:14:55protein synthesis even though an even
- 00:14:58daily protein distri distribution is
- 00:14:59ideal this doesn't mean that consuming
- 00:15:02the same total amount of protein in
- 00:15:04fewer high protein meals is ineffective
- 00:15:07protein distribution is important but
- 00:15:09not vital when you eat a larger dose of
- 00:15:11protein it takes longer to digest but
- 00:15:14your body will eventually use it this is
- 00:15:17contrary to what some people think
- 00:15:18happens when you consume more than 20 to
- 00:15:2125 grams of protein in a single meal
- 00:15:23they think that the excess protein will
- 00:15:25just be excreted by the body and
- 00:15:27otherwise wasted in fact fact a study by
- 00:15:30Dr Luke Van Lon and colleagues found
- 00:15:31that consuming 100 grams of protein
- 00:15:34after exercise led to a more robust and
- 00:15:37prolonged anabolic response than did 25
- 00:15:39grams of protein but had negligible
- 00:15:41effects on amino acid oxidation the
- 00:15:44conclusion from this study was quote the
- 00:15:46magnitude and duration of the anabolic
- 00:15:49response to protein has no upper limit
- 00:15:51in humans and has been severely
- 00:15:53underestimated end quote this dispels a
- 00:15:56few myths about how the body can use
- 00:15:59only 20 to 25 gram of protein at once as
- 00:16:02a practical takeaway a more evenly
- 00:16:04distributed pattern of protein intake
- 00:16:06throughout the day is probably what we
- 00:16:08should be striving for but evidence like
- 00:16:11this highlights why more and more
- 00:16:12experts seem to be aligning on the
- 00:16:14simple fact that the vast majority of us
- 00:16:17athletes or not should be thinking about
- 00:16:19protein intake from the standpoint of
- 00:16:21total daily intake with less overall
- 00:16:23focus on factors like timing or the per
- 00:16:26meal intake another question that people
- 00:16:28have regarding protein timing is whether
- 00:16:30protein needs to be consumed immediately
- 00:16:32after exercise to enhance the effects of
- 00:16:35training this idea is known as the
- 00:16:37anabolic window the anabolic window is a
- 00:16:40period after exercise typically lasting
- 00:16:42from 30 minutes to 2 hours during which
- 00:16:45the body is primed to absorb and utilize
- 00:16:48nutrients particularly protein and
- 00:16:49carbohydrates for muscle repair and
- 00:16:52growth it occurs because the body's
- 00:16:54ability to synthesize protein and
- 00:16:56replenish glycogen stores is heightened
- 00:16:58aided by exercise induced hormonal
- 00:17:00changes like increased insulin levels
- 00:17:03consuming 20 to 40 grams of high quality
- 00:17:06protein often paired with carbohydrates
- 00:17:09can enhance Muscle Recovery and growth
- 00:17:10during the anabolic window or so it was
- 00:17:14once thought recent scientific evidence
- 00:17:16reveals that muscle protein synthesis
- 00:17:18remains significantly elevated for a
- 00:17:20full 24 hours following exercise
- 00:17:23effectively debunking the notion of a
- 00:17:25very narrow anabolic window lasting only
- 00:17:27a few hours furthermore supplementing
- 00:17:30with protein before exercise has the
- 00:17:32same effects on body composition and
- 00:17:34strength compared to supplementing with
- 00:17:36protein immediately after exercise in
- 00:17:39other words there are no meaningful
- 00:17:41differences between pre and post
- 00:17:43exercise protein ingestion this means
- 00:17:45that you're free to choose when you want
- 00:17:47to consume protein in relation to
- 00:17:48exercise so long as your total daily
- 00:17:51intake of protein is adequately High to
- 00:17:53support optimal muscle protein synthesis
- 00:17:56of course there is definitely no
- 00:17:57downside to consuming protein
- 00:17:58immediately after a workout especially
- 00:18:00for people interested in achieving
- 00:18:02marginal gains in strength or muscle
- 00:18:04mass to wrap up our discussion on
- 00:18:06protein timing and distribution I want
- 00:18:07to bring up one more strategy to help
- 00:18:09with muscle building that relates to
- 00:18:11protein distribution and timing
- 00:18:13pre-sleep
- 00:18:14protein there's two ways to look at this
- 00:18:17one way is through the lens of Tim
- 00:18:18restricted eating and the other is
- 00:18:20through the lens of actively optimizing
- 00:18:22for muscle protein synthesis on training
- 00:18:24days it's been shown in Studies by Dr
- 00:18:26Luke Van Lun and colleagues that protein
- 00:18:28consume before bed is digested and
- 00:18:31absorbed overnight it also increases
- 00:18:33overnight muscle protein synthesis rates
- 00:18:36and improves net protein balance in
- 00:18:38people who had performed resistance
- 00:18:39training earlier in the day to enhance
- 00:18:41Muscle Recovery the benefits of
- 00:18:43pre-sleep protein have also been shown
- 00:18:45during chronic resistance exercise
- 00:18:47training consuming about 30 grams of
- 00:18:50protein before bed every night while
- 00:18:52resistance training appears to increase
- 00:18:54muscle mass and muscle strength another
- 00:18:57thing about pre-sleep protein is that it
- 00:18:59does not seem to reduce appetite or
- 00:19:01diminish the muscle protein synthesis
- 00:19:03response at breakfast the next morning
- 00:19:05which may have been a concern for some
- 00:19:07people overall I think pre-sleep protein
- 00:19:09is just one way to increase total daily
- 00:19:11protein intake if you don't like going
- 00:19:13to bed hungry having a low calorie
- 00:19:16protein shake on training days may have
- 00:19:19the benefit of potentially enhancing
- 00:19:20your muscle gain on those training days
- 00:19:23but don't use this as an excuse to go
- 00:19:25wild we should still be mindful about
- 00:19:27the fall and insulin sensitivity that
- 00:19:30happens as we get close to our habitual
- 00:19:32bedtime and this is particularly true if
- 00:19:34you're not actively training so let's
- 00:19:37summarize some key points about protein
- 00:19:39timing and distribution first while it's
- 00:19:42not necessary to consume protein
- 00:19:44immediately after a workout there's no
- 00:19:46harm in doing so for those who exercise
- 00:19:48fasted having a protein Rich meal right
- 00:19:51after may be beneficial ultimately total
- 00:19:54daily protein intake is the most crucial
- 00:19:56Factor second evenly Distributing
- 00:19:59protein across meals is ideal but your
- 00:20:02body can use even large protein meals
- 00:20:05and finally consuming protein before bed
- 00:20:08isn't essential but it can be a helpful
- 00:20:10strategy to boost total daily intake or
- 00:20:12support Muscle Recovery especially in
- 00:20:15those who are actively training all this
- 00:20:17talk about protein lacks context unless
- 00:20:20we discuss the best sources of protein
- 00:20:22particularly when it comes to
- 00:20:23stimulating muscle protein synthesis is
- 00:20:25animal protein better than plant protein
- 00:20:27what about whey protein compared to
- 00:20:29casine protein a highquality protein can
- 00:20:31be efficiently digested and utilized to
- 00:20:33maximize muscle protein synthesis
- 00:20:36several factors influence a protein's
- 00:20:38digestibility including whether it's a
- 00:20:41whole food source an animal-based or
- 00:20:43plant-based protein Source the presence
- 00:20:45of other nutrients like fiber which are
- 00:20:47mainly present in plant foods and the
- 00:20:49amino acid composition of the protein
- 00:20:52when it comes to the amino acid
- 00:20:54composition Lucine is of particular
- 00:20:57importance for protein quality
- 00:20:59the main anabolic component of protein
- 00:21:01is the branch chain amino acid Lucine
- 00:21:03which is a potent stimulator of muscle
- 00:21:05protein synthesis Lucine stimulates
- 00:21:08muscle protein synthesis by activating
- 00:21:10the mtor pathway which is our body's
- 00:21:13Central regulator of cell growth and
- 00:21:15Metabolism in fact Lucine appears to be
- 00:21:18more critical than the total protein
- 00:21:20content of food or supplement in
- 00:21:22determining the muscle protein anabolic
- 00:21:25response this concept is referred to as
- 00:21:27the loosen threshold or the Lucine
- 00:21:29trigger hypothesis which suggests that a
- 00:21:32specific amount of Lucine must be
- 00:21:34consumed to activate muscle protein
- 00:21:36synthesis essentially Lucine acts as a
- 00:21:39switch kickstarting the muscle protein
- 00:21:41building process about 0.25 grams of
- 00:21:45protein per kilogram body weight in a
- 00:21:47single meal provides a saturating dose
- 00:21:50of Lucine and amino acids to stimulate
- 00:21:52muscle protein synthesis for up to 6
- 00:21:54hours that's about 2 to three grams of
- 00:21:57Lucine which can be obtained by
- 00:21:59consuming 20 G of a high quality protein
- 00:22:02like whey protein even though Lucine
- 00:22:04might be the most important amino acid
- 00:22:06for stimulating muscle protein synthesis
- 00:22:08all of the amino acids are required to
- 00:22:10allow the process of muscle protein
- 00:22:11synthesis to sustain for 4 to 6 hours
- 00:22:14loosing is the signal but we also need
- 00:22:17to have all of the building blocks to
- 00:22:19build and repair muscle protein exercise
- 00:22:22lowers that loosing threshold because it
- 00:22:25makes muscle more sensitive to amino
- 00:22:27acids this means a lower dose of Lucine
- 00:22:30and therefore a lower dose of protein is
- 00:22:33needed to reach the Lucine threshold and
- 00:22:35stimulate muscle protein synthesis after
- 00:22:38exercise aging does reduce the
- 00:22:40sensitivity of lucing and other amino
- 00:22:42acids it takes a larger dose of protein
- 00:22:45or Lucine to stimulate the same muscle
- 00:22:47protein synthesis response for someone
- 00:22:49who is older compared to a younger adult
- 00:22:51but again older adults who routinely
- 00:22:54exercise can help overcome this since
- 00:22:56exercise increases sensitivity Lucine if
- 00:22:59you're consuming a variety of
- 00:23:01plant-based and animal-based food
- 00:23:02sources and or supplementing with whey
- 00:23:04protein you probably don't have to worry
- 00:23:07about consuming enough Lucine at each
- 00:23:08meal or throughout the day focusing on
- 00:23:11Whole Foods is the best way to ensure
- 00:23:13you're getting enough Lucine but of
- 00:23:15course if you're concerned adding whey
- 00:23:17protein or Branch chain amino acid
- 00:23:18supplement to your diet is another way
- 00:23:20to get additional Lucine now let's talk
- 00:23:23about the difference between protein
- 00:23:24from animal and plant-based sources
- 00:23:27animal versus plant prot protein whether
- 00:23:29your loyalties are towards a plant-based
- 00:23:31diet or a meat inclusive diet from a
- 00:23:33standpoint of just focusing on
- 00:23:34optimizing for muscle protein synthesis
- 00:23:37an animal Source protein is better it is
- 00:23:39also easier for most people to obtain
- 00:23:41protein from an animal-based food source
- 00:23:43for a few reason for one animal protein
- 00:23:46sources have a greater protein density
- 00:23:49plant-based foods contain less protein
- 00:23:51per gram than most animal based foods
- 00:23:53for example getting 20 gram of protein
- 00:23:55from potatoes means you need to consume
- 00:23:57more than a kilog of potatoes but just
- 00:24:0070 gram of meat like chicken or beef
- 00:24:02contain 20 gram of protein second
- 00:24:05plant-based foods have a lower
- 00:24:07digestability than animal-based Foods
- 00:24:09largely due to the presence of a food
- 00:24:11Matrix consisting of fiber fiber can
- 00:24:13slightly reduce the body's ability to
- 00:24:15extract and utilize protein found in
- 00:24:17plants it also slows the digestion
- 00:24:20process sprouting and fermenting can
- 00:24:23overcome some of this and improve the
- 00:24:25digestibility and absorption of plant
- 00:24:27protein third plant proteins are often
- 00:24:30deficient in one or more of the
- 00:24:32essential amino acids for example lysine
- 00:24:35methionine and most importantly Lucine
- 00:24:39remember that essential amino acids are
- 00:24:41needed to be consumed in the diet to
- 00:24:43build complete proteins in the body a
- 00:24:45lower essential amino acid content means
- 00:24:47that most plant proteins are incomplete
- 00:24:49proteins and stimulate a lower anabolic
- 00:24:52response compared to animal-based
- 00:24:54protein if you're eating plant-based you
- 00:24:57do have options protein needs can be met
- 00:25:00on plant-based diets by supplementing
- 00:25:01with plant-based protein isolates and
- 00:25:03concentrates by consuming a larger
- 00:25:06quantity of protein each day to
- 00:25:07compensate for a lower protein quality
- 00:25:10and also by diversifying the intake of a
- 00:25:12variety of plant-based sources of
- 00:25:14protein so creating complimentary
- 00:25:16proteins that have the right amino acid
- 00:25:18profile despite the lower anabolic
- 00:25:21potential of plant-based protein sources
- 00:25:23studies generally support the idea that
- 00:25:24as long as the total daily protein
- 00:25:26intake is high enough a vegetarian or a
- 00:25:29vegan diet can support daily muscle
- 00:25:31protein synthesis and gains in muscle
- 00:25:33size and strength as much as a diet
- 00:25:35containing animal-based protein but
- 00:25:37because plant protein is lower in
- 00:25:39quality you'll have to consume more food
- 00:25:41overall to reach your daily protein
- 00:25:43intake but Whole Foods aren't the only
- 00:25:45source of protein many people choose to
- 00:25:47obtain their protein through protein
- 00:25:48supplements or protein powder and
- 00:25:50there's a good reason to think that this
- 00:25:51is a fairly sensible practice whey
- 00:25:53protein is one of the most popular
- 00:25:55protein supplements in part because it's
- 00:25:57an extremely high quality protein Source
- 00:25:59whey is a rich source of the essential
- 00:26:01amino acids cysteine and the branch
- 00:26:03chain amino acids Lucine isol leucine
- 00:26:06and veiling Whey also contains several
- 00:26:09bioactive peptides the loosing content
- 00:26:11of whey is what makes it stand out the
- 00:26:13loosing content in way is 50 to 75%
- 00:26:17higher than other protein sources
- 00:26:19compared to the other component of milk
- 00:26:21protein like casin whey protein is more
- 00:26:23rapidly digested and stimulates muscle
- 00:26:25protein synthesis more effectively at r
- 00:26:28and after exercise making it a go-to
- 00:26:31protein source for many athletes the
- 00:26:33slower digestion of casine compared to
- 00:26:35whe isn't necessarily A downside because
- 00:26:37this means casine provides a prolonged
- 00:26:39release of amino acids that can be
- 00:26:41helpful for sustaining the muscle
- 00:26:42protein synthesis response for a longer
- 00:26:44period of time whey and caseine protein
- 00:26:46are both much higher quality protein
- 00:26:48sources than collagen which has a lower
- 00:26:51quality amino acid profile it's rich in
- 00:26:53Glycine and Proline but lacks essential
- 00:26:55amino acids like Lucine furthermore
- 00:26:58collagen does not significantly enhance
- 00:27:00muscle protein synthesis or muscle
- 00:27:02connective protein synthesis at rest or
- 00:27:05after exercise making it a suboptimal
- 00:27:07protein choice for those engaged in
- 00:27:09resistance training and wanting to
- 00:27:11improve skeletal muscle protein
- 00:27:13synthesis it should be clear from our
- 00:27:15discussion thus far that dietary protein
- 00:27:17especially when optimized to suit your
- 00:27:19individual goals and needs has an array
- 00:27:21of health benefits for nearly everyone
- 00:27:24it's performance enhancing anti-aging
- 00:27:26from the standpoint of Frailty
- 00:27:27prevention and can help you lose weight
- 00:27:30however this might come as a surprise to
- 00:27:32many but there is a school of thought
- 00:27:34within the Aging community that too much
- 00:27:36dietary protein increases cancer risk
- 00:27:38and contributes to accelerated aging yet
- 00:27:41today many athletes consume a high
- 00:27:43protein diet and the fact of the matter
- 00:27:45is being an athlete even a recreational
- 00:27:47one is one of the best things we can do
- 00:27:49to age well this is both intuitively and
- 00:27:52scientifically obvious how do we
- 00:27:54reconcile these facts let's get into it
- 00:27:56some researchers argue that a high high
- 00:27:58protein intake especially for meat
- 00:28:00accelerates aging and even raises the
- 00:28:02risk of cancer and early death this idea
- 00:28:05stems largely from laboratory studies
- 00:28:07showing that restricting protein intake
- 00:28:09extends lifespan in animals and
- 00:28:11observational data linking High animal
- 00:28:13protein diets to a higher mortality rate
- 00:28:16supporting this idea one study found
- 00:28:18that middle-aged adults consuming high
- 00:28:21protein diets where 20% of their
- 00:28:23calories came from protein were 75% more
- 00:28:26likely to die from any cause and four
- 00:28:28times more likely to die from cancer
- 00:28:31this is a pretty shocking statistic and
- 00:28:32animal evidence corroborates some of
- 00:28:34this at the mechanistic level however
- 00:28:37there is more to this story in another
- 00:28:39major study middle-aged adults consuming
- 00:28:42high protein diets did show increased
- 00:28:44mortality rates but only if they had
- 00:28:46other unhealthy lifestyle factors like
- 00:28:49obesity smoking heavy drinking or being
- 00:28:52sedentary among healthy people this
- 00:28:55Association disappeared so does a High
- 00:28:58animal protein diet really pose a health
- 00:29:00risk or is it more about what unhealthy
- 00:29:03lifestyle factors exist in someone's
- 00:29:05life this is where it gets interesting
- 00:29:07protein particularly from animal sources
- 00:29:09spikes levels of a hormone called igf-1
- 00:29:12which can help build muscle support
- 00:29:14brain health it enhances muscle repair
- 00:29:17but high igf-1 levels also come with
- 00:29:19potential downsides like promoting the
- 00:29:21survival of pre-cancerous cells and
- 00:29:24potentially allowing them to form cancer
- 00:29:26numerous Studies have found an
- 00:29:28association between elevated igf-1
- 00:29:30levels and an increased risk of various
- 00:29:32cancers so should we cut protein
- 00:29:35drastically to lower igf-1 levels not
- 00:29:38necessarily lowering igf-1 too much can
- 00:29:41come with its own set of risks for
- 00:29:43example calorie restriction which
- 00:29:45significantly drops igf-1 has been
- 00:29:47linked to brain matter loss in non-human
- 00:29:49primates this raises questions about
- 00:29:52whether low igf-1 might have trade-offs
- 00:29:54in terms of brain health so is it better
- 00:29:56to significantly cut protein intake and
- 00:29:59avoid these risks or is there a balance
- 00:30:01to be struck that gives us the best of
- 00:30:03both worlds muscle strength muscle
- 00:30:05repair cognitive health and protection
- 00:30:08against cancer a recent meta analysis by
- 00:30:10Dr wter Longo and colleagues highlighted
- 00:30:13this idea showing a U-shaped
- 00:30:14relationship between igf-1 levels and
- 00:30:17mortality both very high and very low
- 00:30:19igf-1 were linked to higher death rates
- 00:30:22what was the optimal range it was
- 00:30:24actually around 120 to 160 nanog per
- 00:30:28milliliter and to reach this igf-1 sweet
- 00:30:30spot researchers estimated a daily
- 00:30:32protein intake of around 50 to 80 gam
- 00:30:35which is not very much protein not to
- 00:30:38mention this study did not specifically
- 00:30:39look at healthy Physically Active people
- 00:30:42and that's a critical piece to the
- 00:30:44puzzle because a strong response to
- 00:30:46exercise requires igf-1 so it raises a
- 00:30:50philosophical question are these
- 00:30:52recommendations aimed at healthy
- 00:30:54Physically Active individuals or are
- 00:30:56they tailored to people maintaining a
- 00:30:58largely sedentary lifestyle physical
- 00:31:01activity fundamentally changes how igf-1
- 00:31:04behaves in the body exercise lowers
- 00:31:06igf-1 in the bloodstream redirecting it
- 00:31:09to where it can be beneficial like the
- 00:31:11muscle and notably the brain here's why
- 00:31:14that's important when you exercise
- 00:31:16whether it's cardiovascular exercise or
- 00:31:18strength training or high-intensity
- 00:31:20interval training it stimulates muscle
- 00:31:22fibers and increases igf-1 receptor
- 00:31:25density in the muscle cells this makes
- 00:31:28muscle tissue more sensitive to igf-1
- 00:31:31potentially enhancing its uptake while
- 00:31:33this precise mechanism is still being
- 00:31:35explored in research what's clear is
- 00:31:37that exercise increases the ability of
- 00:31:39igf-1 to cross the bloodb brain barrier
- 00:31:43once in the brain igf-1 plays a crucial
- 00:31:46role in promoting neurogenesis that's
- 00:31:48the growth of new brain cells especially
- 00:31:51in regions of the brain like the hypoc
- 00:31:53campus which is important for learning
- 00:31:55and memory exercise doesn't stop there
- 00:31:58exercise particularly intensive exercise
- 00:32:00also raises levels of proteins that bind
- 00:32:03to igf-1 and reduce its bioavailability
- 00:32:06to damage cells that could potentially
- 00:32:08form cancer cells exercise alone causes
- 00:32:11more amino acids to be taken up into
- 00:32:12skeletal muscle which also has the
- 00:32:15effect of reducing circulating igf-1 in
- 00:32:18fact when protein is consumed after
- 00:32:20exercise igf-1 levels do not increase in
- 00:32:24the ensuing 24 hours like they do when
- 00:32:26protein is eaten with without exercising
- 00:32:28beforehand so by channeling how igf-1 is
- 00:32:31used and making it less available to
- 00:32:34potentially stimulate cancer cells
- 00:32:36exercise acts as a protective shield
- 00:32:38regular physical activity has long been
- 00:32:40shown to strongly reduce the risk of
- 00:32:42many types of cancer and this may just
- 00:32:44be one crucial mechanism that accounts
- 00:32:46for that fact furthermore exercise
- 00:32:49enhances the immune system's ability to
- 00:32:50find and destroy cancer cells it lowers
- 00:32:53chronic inflammation which is a known
- 00:32:55risk factor for cancer and it improves
- 00:32:57insulin sensitivity which can further
- 00:32:59influence igf-1 levels so in short
- 00:33:02higher igf-1 levels aren't inherently
- 00:33:04dangerous it's the context that matters
- 00:33:07exercise and a healthy lifestyle change
- 00:33:09the story entirely showing us that igf-1
- 00:33:12can be a powerful Ally for health
- 00:33:14strength and also longevity when Guided
- 00:33:17by an active balanced lifestyle this
- 00:33:19brings us to another important question
- 00:33:21if protein truly is inherently pro-aging
- 00:33:25wouldn't we expect a population with a
- 00:33:27higher protein intake athletes for
- 00:33:29example to experience reduced life
- 00:33:31expectancy but this doesn't appear to be
- 00:33:33the case and in fact the opposite is
- 00:33:35true athletes who we can reasonably
- 00:33:37expect generally consume higher protein
- 00:33:39amounts and are known to have elevated
- 00:33:41igf-1 levels consistently show longer
- 00:33:44lifespans and a better health metric on
- 00:33:46average they live 2 to eight years
- 00:33:48longer than the general population they
- 00:33:50also die less of cancer and
- 00:33:52cardiovascular diseases let's Circle
- 00:33:54back to the amino acid Lucine whether
- 00:33:56we're talking about optimizing muscle
- 00:33:58protein synthesis or controversies in
- 00:34:00the Aging field surrounding igf-1 and
- 00:34:02mtor Lucine is at the heart of it Lucine
- 00:34:05is the critical signal driving robust
- 00:34:07activation of mtor animal protein has a
- 00:34:11lot of lucing and whether you consider
- 00:34:12that a good thing or not actually
- 00:34:14depends on your views of igf-1 and mtor
- 00:34:16mtor plays key roles in skeletal muscle
- 00:34:19growth by driving muscle protein
- 00:34:20synthesis and recovery but this brings
- 00:34:23us to another area where mtor pathway
- 00:34:25has also sparked controversy it's
- 00:34:27potential connection to
- 00:34:29atherosclerosis a study from early 2024
- 00:34:32suggested that a high protein intake
- 00:34:34could accelerate the development of
- 00:34:36atherosclerosis which is the hardening
- 00:34:38and stiffening of arteries the study
- 00:34:40suggested that Lucine which activates
- 00:34:43mtor and muscle tissue to drive muscle
- 00:34:45growth might also activate mtor in the
- 00:34:48vascular system promoting plaque buildup
- 00:34:50through immune Cell Activation the
- 00:34:52important thing to remember is that
- 00:34:54exercise causes Lucine to be taken up by
- 00:34:57muscle where it activates mtor in muscle
- 00:35:00to build and repair muscle rather than
- 00:35:02spending time in the bloodstream
- 00:35:04triggering mtor in the vascular system
- 00:35:07this is yet another example of how being
- 00:35:09physically active versus sedentary
- 00:35:12changes the entire equation it's a
- 00:35:15different game for people who exercise
- 00:35:17regularly okay so I hope it's clear by
- 00:35:19now that the evidence suggesting high
- 00:35:21protein diets are harmful to health is
- 00:35:24not particularly strong when it comes to
- 00:35:26some observational data suggesting a
- 00:35:28potential link between high protein
- 00:35:30intake and risk like cancer this risk
- 00:35:33primarily applies to sedentary
- 00:35:35individuals with other unhealthy
- 00:35:37lifestyle factors like obesity for
- 00:35:40physically active people it's a
- 00:35:42different story exercise ensures that
- 00:35:44protein and Lucine are directed toward
- 00:35:47muscle growth and repair keeping mtor
- 00:35:50activation where it's beneficial in the
- 00:35:52muscles rather than in peripheral
- 00:35:54tissues this explains why athletes
- 00:35:56despite consuming more protein enjoy
- 00:35:58Better Health and longer lifespans than
- 00:36:01the general population the bottom line
- 00:36:03is that for active individuals higher
- 00:36:05protein intake supports performance
- 00:36:07longevity and health all right everyone
- 00:36:09that just about does it for our
- 00:36:11discussion on the science of protein to
- 00:36:13wrap up I want to provide eight of the
- 00:36:15most important takeaways number one for
- 00:36:19most adults a protein intake in the
- 00:36:21range of 1.2 to 1.6 G per kilogram of
- 00:36:24body weight per day should be consumed
- 00:36:27to to support overall health older
- 00:36:29adults athletes and people who want to
- 00:36:31lose weight while sustaining lean body
- 00:36:33mass should consume 1.6 gram per
- 00:36:36kilogram per day or more protein need
- 00:36:39should be calculated based on lean body
- 00:36:41mass or an adjusted body weight that
- 00:36:43reflects a healthy body fat percentage
- 00:36:46this is typically around 12 to 15% for
- 00:36:48men and 20% for women this means that if
- 00:36:51you're not at your ideal weight you
- 00:36:53should determine your protein
- 00:36:54requirements using the target weight
- 00:36:56you're aiming to achieve number two when
- 00:36:59it comes to protein timing the so-called
- 00:37:01anabolic window after exercise isn't as
- 00:37:04narrow as once believe consuming protein
- 00:37:06either before or after a workout is
- 00:37:09effective but also just focusing on
- 00:37:11total daily protein intake is what is
- 00:37:13most important for optimizing resistance
- 00:37:15training gains number three it is ideal
- 00:37:18to try and distribute your protein
- 00:37:19intake evenly across the day aim for
- 00:37:22around 3 to four protein Rich meals each
- 00:37:24containing around 20 to 25 gram of high
- 00:37:27quality protein to stimulate muscle
- 00:37:29protein synthesis for older adults
- 00:37:31increasing each meal's protein content
- 00:37:33to 20 to 30 grams may be advantageous
- 00:37:36due to their higher protein needs and
- 00:37:38anabolic resistance but remember that
- 00:37:41total daily protein intake is much more
- 00:37:43important than how protein is
- 00:37:45distributed throughout the day number
- 00:37:47four consuming protein before bed a
- 00:37:49practice known as pre-sleep protein
- 00:37:51intake this can be particularly
- 00:37:53beneficial for older adults and athletes
- 00:37:55this strategy enhances overnight muscle
- 00:37:57protein synthesis and AIDS in Muscle
- 00:37:59Recovery it contributes to better muscle
- 00:38:02health and performance number five for
- 00:38:04those considering protein
- 00:38:06supplementation high quality sources
- 00:38:08like whey and casine proteins are
- 00:38:09excellent options whey protein is
- 00:38:12rapidly digested and effective at
- 00:38:14stimulating muscle protein synthesis
- 00:38:15making it a great choice post exercise
- 00:38:18or even before bed to provide additional
- 00:38:20boost of amino acids casine protein
- 00:38:23digests more slowly providing a
- 00:38:24prolonged release of amino acids even if
- 00:38:27meeting your protein needs through diet
- 00:38:29alone supplementation can offer targeted
- 00:38:31benefits such as supporting recovery
- 00:38:33during sleep or after very intense
- 00:38:35exercise number six animal proteins are
- 00:38:38generally Superior to plant proteins for
- 00:38:40maximizing muscle protein synthesis due
- 00:38:43to their higher protein density better
- 00:38:45digestability and complete essential
- 00:38:47amino acid profiles particularly their
- 00:38:50Lucine content however vegetarians and
- 00:38:52vegans can still meet their protein
- 00:38:54needs by consuming larger quantities of
- 00:38:56plant-based proteins diversifying their
- 00:38:58protein sources and incorporating
- 00:39:00plant-based protein isolates and
- 00:39:02concentrates to ensure they get all
- 00:39:04their essential amino acids number seven
- 00:39:07concerns about high protein intake
- 00:39:09harming healthy kidneys are largely
- 00:39:11unfounded for individuals without
- 00:39:12pre-existing kidney issues and finally
- 00:39:15number eight despite some schools of
- 00:39:16thought in the longevity field that
- 00:39:18higher protein intakes May reduce
- 00:39:19longevity or promote cancer growth the
- 00:39:22available evidence in humans just isn't
- 00:39:24convincing enough exercise positively
- 00:39:27influen uences how the body uses amino
- 00:39:30acids and growth factors like igf-1 and
- 00:39:32proteins like mtor directing them
- 00:39:34towards the muscle and brain health
- 00:39:36where they're most beneficial that
- 00:39:38brings us to the end of this special
- 00:39:39episode on all things protein I
- 00:39:41sincerely hope that you learned a few
- 00:39:43new things and have a greater
- 00:39:45understanding of the incredibly
- 00:39:46important role that protein plays in
- 00:39:47promoting physical
- 00:39:56health for
- Protein
- Muscle Building
- Insulin Sensitivity
- Metabolic Health
- Longevity
- Resistance Training
- Dietary Recommendations
- Sarcopenia
- Muscle Synthesis
- Plant-based Diet