Sick and Tired, and on Fire Nutrition and Inflammation

00:58:14
https://www.youtube.com/watch?v=I0C3O_7GDtw

摘要

TLDRIn this webinar, Dr. Jamie Wright discusses the critical link between nutrition and inflammation, particularly in the context of chronic diseases. He shares his personal experiences that led him to focus on metabolic health and wellness, emphasizing the importance of dietary choices in managing health outcomes. Dr. Wright highlights the economic burden of chronic diseases and advocates for advanced nutritional testing to better understand individual health needs. He introduces the concept of carbohydrate density and its implications for health, while also addressing the role of gut health in inflammation. The session concludes with practical advice on dietary changes and the significance of epigenetics in health management.

心得

  • 🌱 Nutrition plays a vital role in managing chronic diseases.
  • 💡 Chronic inflammation is often driven by gut health.
  • 📊 Advanced nutritional testing can provide valuable insights.
  • 🚫 Eliminate processed foods to improve gut health.
  • 📈 Lifestyle choices significantly impact health outcomes.
  • 🔍 Understanding carbohydrate density is crucial for health.
  • 🧬 Epigenetics influences gene expression and health.
  • 💪 Physical activity is a key factor in overall well-being.
  • 💰 Chronic diseases have serious economic consequences.
  • 🤝 Collaboration with clients is essential for effective health strategies.

时间轴

  • 00:00:00 - 00:05:00

    The webinar introduces Dr. Jamie Wright, an expert in health and well-being, who discusses the relationship between nutrition and inflammation. He shares his background in OBGYN and his journey towards focusing on metabolic health and wellness.

  • 00:05:00 - 00:10:00

    Dr. Wright shares his personal story of how his wife's health issues led him to explore nutrition and its impact on chronic diseases. He emphasizes the importance of understanding the root causes of health problems rather than just treating symptoms.

  • 00:10:00 - 00:15:00

    He highlights the economic consequences of chronic diseases in the healthcare system, noting that a significant portion of healthcare expenses is related to the treatment of chronic conditions, which are often linked to lifestyle choices.

  • 00:15:00 - 00:20:00

    Dr. Wright discusses the prevalence of non-communicable diseases and how lifestyle choices contribute to these health issues. He emphasizes the opportunity for healthcare professionals to promote health and well-being as a means to combat these diseases.

  • 00:20:00 - 00:25:00

    He explains the concept of chronic low-grade inflammation as a central feature of many chronic diseases and discusses how gut health and diet play a crucial role in driving inflammation.

  • 00:25:00 - 00:30:00

    Dr. Wright introduces the idea of carbohydrate density and its impact on health, arguing that processed foods contribute to chronic diseases and inflammation, while whole foods support better health outcomes.

  • 00:30:00 - 00:35:00

    He discusses the importance of advanced nutritional testing to assess patients' health and tailor interventions, emphasizing that understanding individual nutritional needs is crucial for effective treatment.

  • 00:35:00 - 00:40:00

    Dr. Wright explains the role of genetics and epigenetics in health, highlighting how genetic predispositions can influence disease risk and the importance of personalized approaches to nutrition and health management.

  • 00:40:00 - 00:45:00

    He shares practical strategies for addressing gut health and inflammation, recommending the elimination of certain foods and the importance of whole, natural foods in the diet.

  • 00:45:00 - 00:58:14

    The webinar concludes with a Q&A session where Dr. Wright addresses questions about dietary choices, the impact of fructose, and the acid-alkaline diet, reinforcing the importance of whole foods and balanced nutrition for health.

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思维导图

视频问答

  • What is the main focus of the webinar?

    The webinar focuses on the relationship between nutrition and inflammation, particularly in the context of chronic diseases.

  • Who is Dr. Jamie Wright?

    Dr. Jamie Wright is an osteopathic physician with expertise in health and well-being, focusing on metabolic and nutritional medicine.

  • What are the 'frightening four' foods to eliminate?

    The 'frightening four' foods are sugar, flour, fructose, and oils.

  • How does chronic inflammation relate to gut health?

    Chronic inflammation is largely driven by gut health and the bacteria in the gut responding to food inputs.

  • What is carbohydrate density?

    Carbohydrate density refers to the amount of carbohydrates in food and its impact on health, particularly in relation to chronic diseases.

  • What role does advanced nutritional testing play?

    Advanced nutritional testing helps identify specific deficiencies and tailor dietary recommendations for better health outcomes.

  • How can lifestyle choices impact chronic diseases?

    Lifestyle choices, such as diet and physical activity, significantly influence the development and management of chronic diseases.

  • What is the significance of epigenetics in health?

    Epigenetics involves changes in gene expression that can be influenced by environmental factors, impacting health outcomes.

  • What is the connection between inflammation and chronic diseases?

    Chronic low-grade inflammation is a central feature of many complex chronic diseases.

  • How can one improve gut health?

    Improving gut health involves eliminating processed foods and focusing on whole, natural foods.

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  • 00:00:00
    hello everyone Welcome to our webinar
  • 00:00:02
    entitled sick tired and on fire
  • 00:00:05
    nutrition and inflammation our guest
  • 00:00:08
    speaker today is Dr Jamie
  • 00:00:10
    Wright my name is Christine stuie and
  • 00:00:13
    I'm a medical education specialist at
  • 00:00:15
    Genova's Asheville Branch I'm going to
  • 00:00:18
    serve as the moderator for today's
  • 00:00:20
    webinar we would like to welcome Dr
  • 00:00:23
    Jamie Wright Dr Wright is an
  • 00:00:25
    entrepreneur with expertise in health
  • 00:00:27
    and well-being as an osteopathic
  • 00:00:30
    physician he holds board certification
  • 00:00:32
    in OBGYN and a master's degree in
  • 00:00:34
    metabolic and nutritional medicine from
  • 00:00:36
    the University of South Florida Dr
  • 00:00:39
    Wright has extensively studied
  • 00:00:41
    behavioral therapy brief therapy single
  • 00:00:44
    session therapy behavioral economics and
  • 00:00:47
    holds a certification in neurolinguistic
  • 00:00:50
    programming as the president of right
  • 00:00:52
    check Wellness Solutions Dr wght is
  • 00:00:54
    focused on contributing to the health
  • 00:00:56
    status of our nation and World by
  • 00:00:58
    creating engaging business models that
  • 00:01:00
    allow corporations to realize the value
  • 00:01:03
    of well-being as an economic
  • 00:01:05
    strategy Dr Wright has a small Private
  • 00:01:08
    Practice called the center for balance
  • 00:01:10
    living the focus of this Clinic is to
  • 00:01:13
    improve individual health out outcomes
  • 00:01:15
    through the application of metabolic
  • 00:01:17
    Health principles strategic planning and
  • 00:01:20
    client
  • 00:01:22
    collaboration great all right well um
  • 00:01:27
    it's a pleasure to be here I'm in the
  • 00:01:29
    mountains in ceto Springs and um I
  • 00:01:32
    joined a new Venture about 6 months ago
  • 00:01:35
    to develop a health and well-being
  • 00:01:38
    Center at a really magical place called
  • 00:01:41
    The Garden of the Gods Club and Resort
  • 00:01:44
    here in Colorado Springs so every day I
  • 00:01:46
    get to come and look at uh these amazing
  • 00:01:49
    rock formations um called The Garden of
  • 00:01:52
    the Gods as well as the backdrop of
  • 00:01:54
    Pikes Peak and you know I I came from
  • 00:01:57
    Michigan so um right around February is
  • 00:02:01
    when when you want to you know uh make
  • 00:02:04
    alternative life plans because you
  • 00:02:06
    haven't seen the the sun in weeks and
  • 00:02:09
    here in Colorado Springs it's uh
  • 00:02:12
    fabulously gorgeous every single day um
  • 00:02:17
    my back background is In Obstetrics and
  • 00:02:18
    Gynecology and I remain board certified
  • 00:02:20
    however I haven't played um played that
  • 00:02:22
    role in about five years ago
  • 00:02:25
    and I want to give you a little bit of a
  • 00:02:27
    backstory on why I do what I do and how
  • 00:02:30
    I got here um because it'll help you
  • 00:02:34
    frame the information that I'm going to
  • 00:02:35
    give you um and indeed this should be a
  • 00:02:38
    nice um fun um insightful talk I hope
  • 00:02:42
    and I hope when you go back to your
  • 00:02:44
    patients here in the afternoon you'll
  • 00:02:46
    have uh maybe one or two different ways
  • 00:02:48
    to look at your client think about your
  • 00:02:51
    client um and how to apply some more
  • 00:02:54
    advanced testing and the assessment of
  • 00:02:56
    your of your clients so when I was about
  • 00:02:58
    3 years into my obgy
  • 00:03:00
    practice I found myself in a unique
  • 00:03:03
    position um I was a solo OBGYN in a
  • 00:03:06
    small uh town in uh rural Louisiana I
  • 00:03:09
    had four young children um I was really
  • 00:03:12
    exhausted after you know uh being a solo
  • 00:03:15
    practitioner for so long and then uh my
  • 00:03:17
    wife went into the bed sort of
  • 00:03:19
    mysteriously and uh she was on crutches
  • 00:03:21
    about half the time um had shaking
  • 00:03:24
    chills weird neurological symptoms
  • 00:03:26
    fevers all the time and this went on for
  • 00:03:29
    about a year year and a half um and at
  • 00:03:31
    one point she was on you know five or
  • 00:03:33
    six different uh pain and neurologic
  • 00:03:36
    management drugs uh we had gotten
  • 00:03:38
    nowhere um as an OBGYN I had diagnosed
  • 00:03:41
    her with quote Interstitial cystitis
  • 00:03:44
    which you know I now know not to
  • 00:03:46
    actually be anything um in terms of uh
  • 00:03:50
    you know it has different root causes
  • 00:03:52
    than we're we understand as
  • 00:03:55
    OBGYNs and I determined that I just
  • 00:03:57
    couldn't live like that anymore and so
  • 00:04:00
    um I happened to fall into the American
  • 00:04:04
    Academy anti-aging medicine went to a
  • 00:04:06
    conference and and really um took to the
  • 00:04:11
    concepts that I was learning and within
  • 00:04:13
    about six months using nutrition I mean
  • 00:04:16
    this was seven eight years ago so I was
  • 00:04:18
    pretty clueless um I was just doing
  • 00:04:20
    fumbling around with thyroid and
  • 00:04:22
    fumbling around with uh some nutritional
  • 00:04:25
    stuff and um cleaning up the diet in the
  • 00:04:28
    home and within about six months my
  • 00:04:30
    wife's Health dramatically improved um
  • 00:04:33
    and that's when I saw the vision for you
  • 00:04:35
    know this is really a worthwhile uh
  • 00:04:37
    field to get into because you can truly
  • 00:04:40
    help people instead of treating symptoms
  • 00:04:42
    and I know you're all drinking that
  • 00:04:43
    Kool-Aid anyway but um in around 2010 I
  • 00:04:47
    set off to um go deeply into this field
  • 00:04:51
    and find um deeper help for my family
  • 00:04:53
    and it turned out that my wife and two
  • 00:04:55
    of my children had Lyme disease and this
  • 00:04:57
    took took us about we didn't figure that
  • 00:04:59
    out until about 2013 but I really
  • 00:05:01
    developed my whole career around um
  • 00:05:04
    helping my family get well and then took
  • 00:05:07
    what I was learning and translated it
  • 00:05:10
    into uh practices and methods with my
  • 00:05:15
    patients the concept that emerged with
  • 00:05:18
    me as I began developing my corporate
  • 00:05:19
    wellness program and and working with a
  • 00:05:23
    a very large International manufacturing
  • 00:05:25
    firm is that these healthc care problems
  • 00:05:27
    that we see dayto day practice we see
  • 00:05:30
    individual by individual but when you go
  • 00:05:32
    up to a higher level what you realize is
  • 00:05:34
    there are severe and serious Economic
  • 00:05:37
    Consequences and indeed um you know when
  • 00:05:40
    you have 75% of your uh country's gross
  • 00:05:43
    um health care expenses going to the the
  • 00:05:48
    treatment of chronic disease uh that
  • 00:05:51
    probably represents a real threat to
  • 00:05:54
    your economy because it's simply not
  • 00:05:57
    sustainable um for instance diabetes
  • 00:05:59
    care in 2002 was around
  • 00:06:02
    $133,000 per year per individual um now
  • 00:06:06
    that's probably changed I don't know if
  • 00:06:08
    it's more or less now because of changes
  • 00:06:09
    in healthc care reimbursement um but
  • 00:06:12
    certainly this is the number that in my
  • 00:06:14
    corporate wellness world when I was
  • 00:06:16
    working with that large manufacturing
  • 00:06:17
    firm these were the numbers that we
  • 00:06:19
    talked about in terms of the treatment
  • 00:06:22
    or the cost of of single individuals
  • 00:06:24
    with complex chronic
  • 00:06:26
    diseases behavioral choices also o
  • 00:06:29
    result in extremely um
  • 00:06:33
    extreme sorry extremely costly
  • 00:06:35
    conditions and indeed what I have
  • 00:06:39
    discovered or come to believe is that
  • 00:06:41
    virtually all of these conditions are um
  • 00:06:45
    based on behavioral
  • 00:06:46
    choices when I was in OBGYN um in well
  • 00:06:50
    actually let's go back to medical school
  • 00:06:52
    remember when we were in medical school
  • 00:06:53
    they they talked to us about risky
  • 00:06:55
    behaviors and it would you know it
  • 00:06:56
    revolved around things like sex drugs
  • 00:06:59
    and rock roll right well uh 2014 here
  • 00:07:02
    the National Association of chronic
  • 00:07:04
    disease directors published these risky
  • 00:07:07
    behaviors
  • 00:07:09
    and this is all self-inflicted stuff
  • 00:07:12
    that's that we're doing every day
  • 00:07:15
    processed food eating sedentary tobacco
  • 00:07:18
    and then family history and I think
  • 00:07:20
    honestly the first two things uh have
  • 00:07:22
    probably killed and will continue to
  • 00:07:24
    kill or harm more individuals and their
  • 00:07:28
    quality of life more families and their
  • 00:07:30
    Financial Security and quality of life
  • 00:07:32
    than tobacco ever thought about but you
  • 00:07:34
    know who
  • 00:07:36
    knows fortunately we have large
  • 00:07:39
    corporations here to help us solve these
  • 00:07:42
    problems and help our families get
  • 00:07:45
    fit yes indeed we have some um
  • 00:07:48
    significant paradoxes in our culture and
  • 00:07:52
    I think since I found this article um a
  • 00:07:55
    year or so ago the uh someone out there
  • 00:07:58
    called called this company out about the
  • 00:08:01
    the um Paradox here and I'm not seeing
  • 00:08:04
    these ads
  • 00:08:06
    anymore we're dealing with what's called
  • 00:08:09
    non-communicable diseases these are the
  • 00:08:12
    diseases of choice as I call them and
  • 00:08:14
    and I say that a little bit probably too
  • 00:08:17
    generally and a little bit too
  • 00:08:19
    categorically so forgive me for that but
  • 00:08:21
    the the general concept is this on
  • 00:08:25
    every continent except Africa these
  • 00:08:29
    diseases of Lifestyle these highly
  • 00:08:32
    modifiable diseases are killing more
  • 00:08:34
    people than communicable diseases
  • 00:08:36
    maternal mortality perinal mortality and
  • 00:08:39
    nutritional conditions sort of all
  • 00:08:42
    combined so it's actually not a real big
  • 00:08:45
    problem what it is is a massive massive
  • 00:08:48
    massive massive opportunity for people
  • 00:08:51
    like us who believe that the natural
  • 00:08:54
    human state is one of health and
  • 00:08:56
    well-being who believe that people
  • 00:08:58
    should be living
  • 00:09:00
    and can live enriched meaningful
  • 00:09:02
    purposeful
  • 00:09:04
    lives so physical activity alone looking
  • 00:09:07
    at it's simply getting people moving
  • 00:09:09
    better can address um you know a huge
  • 00:09:13
    amount of the global health and death
  • 00:09:16
    burden and here's how I've come to see
  • 00:09:19
    it as I've studied a wide breadth of
  • 00:09:21
    metabolic and nutritional
  • 00:09:23
    medicine physical activity is a behavior
  • 00:09:26
    just like being sedentary is a behavior
  • 00:09:30
    so they're both choices when I am
  • 00:09:32
    physically active and the degree to
  • 00:09:35
    which I am physically active I'm sending
  • 00:09:37
    signals into my body down into the
  • 00:09:40
    cellular level down into the genetic and
  • 00:09:42
    epigenetic level that says I'm alive and
  • 00:09:46
    when I choose to be sedentary I'm
  • 00:09:48
    sending a different kind of a signal
  • 00:09:51
    into my cellular
  • 00:09:53
    infrastructure
  • 00:09:55
    so the the outcome of Being Fit and Well
  • 00:09:59
    well um and having
  • 00:10:01
    wellbeing is um only a consequence of
  • 00:10:05
    the Upstream inputs and physical
  • 00:10:08
    activity is an upstream input that you
  • 00:10:11
    can voluntarily control what you the
  • 00:10:14
    food that you put in your mouth is an
  • 00:10:16
    upstream input that you can control the
  • 00:10:18
    case that I'm making is
  • 00:10:21
    this the case was made very clearly in
  • 00:10:24
    1926 in a little uh book called toxemia
  • 00:10:28
    explained
  • 00:10:29
    and this book makes a fantastic case
  • 00:10:33
    that diseases of a man's own making and
  • 00:10:35
    this is a short book you can find it in
  • 00:10:37
    PDF
  • 00:10:38
    online and what you'll discover if you
  • 00:10:41
    choose to read it is that this
  • 00:10:43
    doctor is saying the same things as
  • 00:10:47
    we're saying now and in fact he says
  • 00:10:49
    many of the things about the the health
  • 00:10:52
    and wellness industry that was emerging
  • 00:10:54
    then kind of the snake oil salesman or
  • 00:10:57
    the one the one pill to cure it all
  • 00:10:59
    perspective as we have going on now and
  • 00:11:02
    now the mechanism of dissemination of
  • 00:11:04
    this kind of inaccurate information is
  • 00:11:06
    the internet and back then it was you
  • 00:11:09
    know probably the roving salesman and
  • 00:11:11
    and um you know propaganda
  • 00:11:16
    pieces but if you begin to view your
  • 00:11:20
    patients or yourself from the standpoint
  • 00:11:23
    that you are well and that they are
  • 00:11:26
    well it changes your perspective and
  • 00:11:29
    then you layer in this concept that
  • 00:11:31
    diseas is of man's own
  • 00:11:34
    making it may significantly alter how
  • 00:11:38
    you're approaching the most important
  • 00:11:40
    Global problem of the 21st century which
  • 00:11:43
    is non-communicable
  • 00:11:46
    diseases so what is the root cause
  • 00:11:48
    what's going on here well again I I'm a
  • 00:11:52
    I tend to be a generalist in my thinking
  • 00:11:54
    and then drill down into details from
  • 00:11:56
    there so I'm going to kind of uh make
  • 00:11:59
    some sweeping um generalizations here
  • 00:12:02
    and one of the sweeping generalizations
  • 00:12:04
    is that um it appears to me from my
  • 00:12:06
    research that most complex chronic
  • 00:12:08
    diseases have a central feature which is
  • 00:12:11
    called chronic low-grade inflammation
  • 00:12:14
    and chronic
  • 00:12:15
    inflammation um is is tied
  • 00:12:20
    to um every disease of Aging that I've
  • 00:12:23
    been able to to find regardless of the
  • 00:12:26
    body system involved and so then the
  • 00:12:29
    question began to emerge several years
  • 00:12:30
    ago for me is um what's driving this
  • 00:12:34
    inflammation and the um the most basic
  • 00:12:38
    um driver that I've come up with that
  • 00:12:41
    has helped me uh change my own health
  • 00:12:44
    improve my family's health and give
  • 00:12:46
    patients wise counsel that always has a
  • 00:12:50
    positive Ina impact is this inflammation
  • 00:12:53
    is largely driven from the gut and it's
  • 00:12:56
    largely driven from what the bacteria in
  • 00:12:59
    the gut are doing in response to the
  • 00:13:02
    input that we call
  • 00:13:05
    food so I would recommend this article
  • 00:13:08
    to you um I've got a couple articles in
  • 00:13:10
    here that I recommend Ian spread Berry's
  • 00:13:13
    article on ancestral diets and
  • 00:13:16
    inflammatory disbiosis and what Ian does
  • 00:13:19
    here is he pulls together a wide variety
  • 00:13:22
    of um uh metabolic and medical research
  • 00:13:28
    um Concepts
  • 00:13:30
    that really uh help us understand where
  • 00:13:32
    this chronic inflammatory burden is
  • 00:13:34
    coming from and within this body of work
  • 00:13:37
    he talks about a concept called
  • 00:13:39
    carbohydrate density now this is not
  • 00:13:42
    glycemic index um you my personal
  • 00:13:47
    experience in working with the glycemic
  • 00:13:48
    index are trying to use that as a tool
  • 00:13:51
    um to help me uh architect patients care
  • 00:13:55
    or help them control their own um their
  • 00:13:59
    own diet and their and and their own
  • 00:14:01
    problems in terms of diet I found the
  • 00:14:04
    glycemic
  • 00:14:05
    index basically useless um I'm not
  • 00:14:08
    saying that it's useless it didn't work
  • 00:14:10
    for me and it didn't seem to be working
  • 00:14:11
    for my clients this concept of
  • 00:14:13
    carbohydrate
  • 00:14:15
    density um moves you away from Counting
  • 00:14:18
    carbohydrates and moves you into some
  • 00:14:20
    high level
  • 00:14:21
    Concepts ancestral people groups did not
  • 00:14:25
    have chronic disease for the most part
  • 00:14:28
    uh they didn't don't don't develop
  • 00:14:30
    hypertension they don't develop
  • 00:14:31
    metabolic diseases like diabetes and
  • 00:14:34
    dyspan metabolic syndrome for the most
  • 00:14:36
    part when you do autopsies on 50 or 60
  • 00:14:39
    year old men um you know they don't have
  • 00:14:42
    fatty streaking of the aoro they don't
  • 00:14:43
    have AOS scerotic
  • 00:14:45
    disease um and there's some things that
  • 00:14:48
    they don't do and some things that they
  • 00:14:49
    do and one of the things that they do is
  • 00:14:51
    they eat uh intact whole food I call
  • 00:14:55
    this a natural state diet or foods that
  • 00:14:58
    show up in nature or things that God
  • 00:15:00
    made um whatever Concepts you can get
  • 00:15:03
    around to your clients to help them
  • 00:15:05
    realize that when they pick up something
  • 00:15:07
    that doesn't look like it shows up in
  • 00:15:09
    nature it's probably not a natural state
  • 00:15:12
    food and therefore it probably has some
  • 00:15:14
    Downstream consequence to their
  • 00:15:16
    physiology that will probably not be
  • 00:15:20
    good um you look up here where things
  • 00:15:23
    are shaded and the you know the
  • 00:15:27
    the um the grams of carbohydrates per
  • 00:15:31
    100 G of food begins to escalate
  • 00:15:34
    significantly and you can see here that
  • 00:15:37
    cheeseburgers and milkshakes and pizzas
  • 00:15:40
    and nachos the these don't show up in
  • 00:15:44
    nature what about multi-grain bread
  • 00:15:46
    isn't that healthy for me well basically
  • 00:15:49
    Ian Ian makes a really strong case and
  • 00:15:51
    shows research around of the concept
  • 00:15:55
    that um virtually every study that
  • 00:15:57
    looked at grain based d s uh in the
  • 00:16:00
    ancestral people groups showed a link to
  • 00:16:01
    chronic disease or metabolic disease or
  • 00:16:03
    inflammation or leptin resistance as a
  • 00:16:05
    marker of impending metabolic disease
  • 00:16:09
    so really this is the free burden or you
  • 00:16:12
    could consider this the free burden of
  • 00:16:14
    I'm sorry the the um losing the word
  • 00:16:17
    here the the available that's the word
  • 00:16:20
    that I want the available um sugar um in
  • 00:16:24
    100 gram of food that you're eating now
  • 00:16:27
    why does that matter well that matters
  • 00:16:29
    is because you're not just feeding
  • 00:16:31
    yourself right you're feeding
  • 00:16:33
    these 100 trillion bacteria that are
  • 00:16:37
    living in your gut and you know when you
  • 00:16:40
    when you're back doing um Regular old
  • 00:16:43
    biology and microbiology you know when
  • 00:16:45
    you wanted to grow bacteria over
  • 00:16:47
    overnight or within 48 Hours you didn't
  • 00:16:50
    you know stick them in a Petri dish with
  • 00:16:51
    a
  • 00:16:52
    cucumber the petri dish has free
  • 00:16:56
    macronutrients and micronutrients in it
  • 00:16:58
    freely available sugars and and proteins
  • 00:17:02
    so when we're eating processed foods
  • 00:17:04
    we're giving our gut microbiome or the
  • 00:17:07
    microbiota or the bacteria in the gut
  • 00:17:10
    free energy um and those bacteria can
  • 00:17:14
    overgrow and when they begin to overgrow
  • 00:17:17
    especially in the small gut they make
  • 00:17:19
    their um normal byproducts one of which
  • 00:17:22
    is lipopolysaccharide Toxin or LPS Toxin
  • 00:17:26
    and I'm going somewhere with this so
  • 00:17:27
    don't don't lose me in the weeds don't
  • 00:17:29
    have slides for this but this is an
  • 00:17:30
    important concept so these bacteria your
  • 00:17:33
    clients are feeding the bacteria sugar
  • 00:17:35
    the bacteria is overgrowing making these
  • 00:17:37
    toxins the toxins get in the in the
  • 00:17:39
    lymphatic system and um then get into
  • 00:17:42
    your circulation and it makes the body
  • 00:17:44
    think you have a little low grade
  • 00:17:46
    infection and that's what is stimulating
  • 00:17:49
    the production of C reactive protein
  • 00:17:52
    that's why you see an elevated CRP in so
  • 00:17:54
    many people um the the mevalonate
  • 00:17:57
    pathway which is the LD L production
  • 00:18:00
    pathway um turns on because LDL acts as
  • 00:18:03
    an antioxidant antiviral antiparasitic
  • 00:18:06
    and is actually sort of acting as an
  • 00:18:08
    armor of the immune system so when you
  • 00:18:10
    grasp this concept of um carbohydrate
  • 00:18:15
    density and you follow it through to the
  • 00:18:17
    end result of laboratory abnormalities
  • 00:18:20
    that we call metabolic diseases or
  • 00:18:22
    complex chronic diseases you see the
  • 00:18:25
    connection you see the connection
  • 00:18:28
    between inflammation and virtually every
  • 00:18:31
    degenerative
  • 00:18:32
    disease um and I have come to really uh
  • 00:18:37
    think of chronic inflammation and
  • 00:18:38
    metabolic disease
  • 00:18:41
    synonymously um C reactor protein by the
  • 00:18:44
    way is an independent risk factor for
  • 00:18:46
    cardiovascular disease and that was
  • 00:18:48
    proven out in one of the biggest studies
  • 00:18:50
    um in a tvist Statin study I'm not a big
  • 00:18:53
    pharmaceutical guy but um where they
  • 00:18:56
    they um statistically show that C
  • 00:18:59
    reactive protein um is as potent as LDL
  • 00:19:03
    levels um in predicting um risk for
  • 00:19:06
    cardiovascular disease as an example if
  • 00:19:09
    you had an individual with an LDL under
  • 00:19:12
    100 but their CRP was over 2.0 they had
  • 00:19:14
    the same risk as if they had an LDL
  • 00:19:18
    above about 130 for heart disease and
  • 00:19:21
    then when you add CRP and LDL you um
  • 00:19:25
    compound the risk and then other things
  • 00:19:28
    like Uric acid and
  • 00:19:29
    homocystine as well so these metabolic
  • 00:19:33
    diseases including metabolic syndrome
  • 00:19:35
    are pro-inflammatory um conditions and
  • 00:19:39
    it does not all revolve around visceral
  • 00:19:41
    fat remember they had to get inflamed to
  • 00:19:45
    put on that fat in the first place and
  • 00:19:48
    that inflammation started in the
  • 00:19:50
    gut now let's talk about the typical
  • 00:19:52
    assessment so I want to go back to my
  • 00:19:53
    OBGYN days and my really sophisticated
  • 00:19:56
    nutritional assessment back then was
  • 00:19:59
    look at the lab sheet and circle what um
  • 00:20:03
    what's on that lab sheet and then
  • 00:20:05
    honestly I didn't really know that much
  • 00:20:07
    to do with it um so I call this the
  • 00:20:10
    expeditious um neutraal if you will or
  • 00:20:13
    the maybe this is the traditional Dax
  • 00:20:16
    neutraal um by the time you see these
  • 00:20:21
    conditions of nutritional deficiency
  • 00:20:23
    that that the traditional medical world
  • 00:20:26
    looks for and the horse has been out of
  • 00:20:28
    the barn for a really long time and
  • 00:20:30
    we've you know we've really missed the
  • 00:20:32
    boat by the time you see like I've never
  • 00:20:34
    seen night blindness due to vitamin A
  • 00:20:37
    deficiency I've never seen rickets um
  • 00:20:41
    and so what what we're really talking
  • 00:20:43
    about here for the remainder of the
  • 00:20:45
    webinar is
  • 00:20:48
    um how can we and why should we take a
  • 00:20:52
    deeper look at the nutritional status of
  • 00:20:56
    our clients and when might it be be
  • 00:20:59
    appropriate and then the second question
  • 00:21:01
    is um how can we understand uh what
  • 00:21:05
    types of systems might need some extra
  • 00:21:08
    Focus because the client has genetic
  • 00:21:11
    predisposition so we're going to talk a
  • 00:21:13
    little bit about nutritional testing and
  • 00:21:15
    a little bit about genetics and then I'm
  • 00:21:18
    going to go through a bit of a case
  • 00:21:19
    study and then we're going to wrap it
  • 00:21:23
    up
  • 00:21:26
    um so one of the question questions is
  • 00:21:29
    um why would we want to gather
  • 00:21:32
    sophisticated information like uh this
  • 00:21:35
    neutraal test here on the say the fatty
  • 00:21:39
    acid status of a
  • 00:21:41
    patient why would we want to know what
  • 00:21:45
    um nutritional elements in terms of
  • 00:21:48
    minerals what the status is there how
  • 00:21:51
    about the toxic
  • 00:21:53
    elements
  • 00:21:55
    um I'll tell you why uh I'm a
  • 00:21:57
    businessman and there's a concept and I
  • 00:21:59
    think this was promoted by Peter Ducker
  • 00:22:02
    he said this first you can't manage what
  • 00:22:05
    you don't measure so if if I'm placing
  • 00:22:09
    people
  • 00:22:10
    on uh random vitamins or large amounts
  • 00:22:14
    of vitamins or doing the vitamin shotgun
  • 00:22:16
    approach that can that can work and that
  • 00:22:18
    can help I think it tends to help um the
  • 00:22:22
    the loow hanging fruit clients as I call
  • 00:22:24
    them you know they're not deeply
  • 00:22:26
    inflamed they don't have autoimmune
  • 00:22:27
    disease they don't don't have any deep
  • 00:22:29
    genetic things going on they're just
  • 00:22:30
    sort of you know chronically fatigued um
  • 00:22:34
    a little bit of you know adrenal
  • 00:22:35
    suppression from chronic stress and
  • 00:22:38
    their nutrients are suboptimal and you
  • 00:22:40
    get them on some vitamins and and they
  • 00:22:42
    turn around in 48 hours a week two weeks
  • 00:22:45
    six weeks that type of a thing and that
  • 00:22:47
    was my personal experience with
  • 00:22:49
    myself um but as you progress in the
  • 00:22:52
    field and I'm not sure where you all are
  • 00:22:53
    at in in terms of how long you've been
  • 00:22:56
    in this field but um so no dis respect
  • 00:22:58
    to anyone but I'm just more thinking
  • 00:23:00
    about my my progression in the last
  • 00:23:02
    seven years um in becoming um a a
  • 00:23:05
    metabolic expert if if you could really
  • 00:23:07
    become
  • 00:23:08
    that so once you get done with the low
  • 00:23:11
    hanging fruit people um you know the the
  • 00:23:14
    menopausal ladies that really respond
  • 00:23:16
    nicely to some natural hormone therapy a
  • 00:23:18
    little bit of thyroid and some vitamins
  • 00:23:20
    or the The Chronic fatiguer that comes
  • 00:23:22
    in that you get them off gluten you put
  • 00:23:24
    them on some vitamins and their life
  • 00:23:25
    changes then you start uh having to deal
  • 00:23:29
    with the more complicated and
  • 00:23:31
    challenging
  • 00:23:33
    people and they can really present a
  • 00:23:36
    problem
  • 00:23:38
    um because there's a learning curve
  • 00:23:40
    there so how do you how do you go deep
  • 00:23:43
    with this people and deal with the
  • 00:23:44
    behavioral and psychological elements
  • 00:23:48
    how do you help them deal with how
  • 00:23:50
    they've architected their environment
  • 00:23:52
    and how that environment supports them
  • 00:23:54
    doing the things putting the inputs in
  • 00:23:57
    that are causing them metabolic
  • 00:23:59
    dysfunctions in the chronic disease how
  • 00:24:01
    do you assess their physiology in a way
  • 00:24:03
    that both can allow you to educate them
  • 00:24:05
    put the pieces of the puzzle together as
  • 00:24:07
    well as treat them and apply a
  • 00:24:09
    therapeutic regimen in the right
  • 00:24:12
    direction and so you know I'm not a big
  • 00:24:14
    advocate of tons of testing on
  • 00:24:17
    people but when you get into more
  • 00:24:19
    complicated cases when you've tried
  • 00:24:22
    things that worked on other people that
  • 00:24:24
    seem similar but they're not working
  • 00:24:26
    this is where more advanced testing can
  • 00:24:27
    come into play and then there's another
  • 00:24:30
    crowd of uh people that I would put in
  • 00:24:32
    the Executive Health world or the Peak
  • 00:24:34
    Performance world and Gathering um more
  • 00:24:37
    detailed information just like you would
  • 00:24:40
    if you were going to buy a business you
  • 00:24:41
    would do a financial analysis you would
  • 00:24:43
    do a forensic financial analysis of that
  • 00:24:45
    company before you bought that company
  • 00:24:48
    so that you knew exactly where your
  • 00:24:51
    risks are and therefore you knew exactly
  • 00:24:53
    where to go forward this is what this
  • 00:24:55
    kind of testing can help you do now
  • 00:24:59
    um what I've had up on the screen here
  • 00:25:00
    as I've been doing a little bit of U
  • 00:25:03
    highle talking is the kreb cycle and uh
  • 00:25:07
    I want to show you I just want to
  • 00:25:10
    demonstrate to you how you can use a
  • 00:25:11
    test like neutraal and this graph to
  • 00:25:14
    teach people that the things they're
  • 00:25:16
    putting in their body are causing
  • 00:25:19
    function or limiting function and so
  • 00:25:23
    what what they what we know is that this
  • 00:25:25
    little cycle turns around and around is
  • 00:25:27
    is what is predominantly responsible for
  • 00:25:29
    making the energy currency of the cell
  • 00:25:33
    then we have this little thing here that
  • 00:25:34
    we drink often every day um so we're
  • 00:25:38
    we're drinking sugar now what's the
  • 00:25:40
    connection between drinking sugar and
  • 00:25:42
    making energy in the cell well I'll tell
  • 00:25:44
    you fructose um goes through an enzyme
  • 00:25:47
    called keto hecto fructokinase and it
  • 00:25:50
    has to be
  • 00:25:51
    phosphorilated and So within the cell
  • 00:25:53
    fructose is phosphorated it uses ATP to
  • 00:25:56
    do that there's no negative feedback
  • 00:25:59
    here so this enzyme just runs if
  • 00:26:01
    fructose shows up fructose goes through
  • 00:26:04
    this pathway until there's no more
  • 00:26:06
    fructose to go through and therefore
  • 00:26:08
    this this um pathway demands
  • 00:26:12
    ATP which is fine if you eat an apple
  • 00:26:16
    but if you're drinking 50 or 60 or 100
  • 00:26:19
    or 150 grams of fructose a day um what
  • 00:26:24
    you're doing is you're putting a very
  • 00:26:25
    substantial energy demand um on this on
  • 00:26:29
    the body's physiology of the cellular
  • 00:26:31
    level now it's interesting too to look
  • 00:26:33
    at what happens to that ATP skel and as
  • 00:26:36
    it's broken down and used up it turns
  • 00:26:38
    into uric acid uric acid is a risk
  • 00:26:42
    marker for both diabetes and metabolic
  • 00:26:44
    syndrome uric acid on the outside of the
  • 00:26:46
    cell acts as an antioxidant that's kind
  • 00:26:50
    of good uric acid within the cell is a
  • 00:26:54
    prooxidant and actually impairs the
  • 00:26:57
    mitochondrial
  • 00:26:59
    um TCA or citric acid
  • 00:27:01
    cycle impaired um citric acid cycle
  • 00:27:06
    increases citrate as it's as a substrate
  • 00:27:10
    right the wheel can't turn so you get a
  • 00:27:12
    buildup of citrate and citrate gets
  • 00:27:15
    metabolized and stored as a triglyceride
  • 00:27:19
    fructose gets metabolized and stored as
  • 00:27:22
    a triglyceride so look at the amount of
  • 00:27:24
    derangements all going on around
  • 00:27:27
    fructose
  • 00:27:28
    consumption um where you're having
  • 00:27:31
    oxidant stress promoted intracellularly
  • 00:27:34
    you're impeding mitochondrial and energy
  • 00:27:37
    production which is needed up here and
  • 00:27:39
    you're storing uh essentially sugar fat
  • 00:27:43
    in the cells what do we know this as we
  • 00:27:46
    know this as um Fetti liver right and
  • 00:27:49
    you know it's amazing to me how many
  • 00:27:51
    people don't seem to get what's really
  • 00:27:53
    driving fatty Li I see patients all the
  • 00:27:56
    time here in the clinic who have to many
  • 00:27:59
    doctors and told that it's they get
  • 00:28:00
    liver biopsies to prove it's fatty liver
  • 00:28:02
    I don't I don't understand this these
  • 00:28:04
    are things that we can do to help people
  • 00:28:05
    so you can show the patient that you
  • 00:28:08
    know these toxic elements um impede the
  • 00:28:12
    functioning of the energy Cycles these
  • 00:28:14
    nutrients are imperative to helping this
  • 00:28:18
    wheel turning creating energy and what
  • 00:28:20
    you're putting into your body in terms
  • 00:28:22
    of processed food or whole food has a
  • 00:28:24
    direct impact at this level okay I
  • 00:28:27
    apologize I kind of went into the weeds
  • 00:28:29
    there but I find that fascinating um so
  • 00:28:33
    yeah let's go back to why we would do
  • 00:28:35
    Advanced testing you have this
  • 00:28:37
    23-year-old uh G that comes into your
  • 00:28:39
    practice you probably know that she
  • 00:28:41
    needs vitamin D why why is that because
  • 00:28:44
    the thousand people that you've tested
  • 00:28:46
    about three of them actually had optimal
  • 00:28:47
    vitamin D levels you know in the 60 80
  • 00:28:50
    or 100 or what whatever you think it
  • 00:28:53
    is but how would you know that this
  • 00:28:56
    young lady needed coenzyme Q 10 you know
  • 00:28:59
    because to me I think over 50
  • 00:29:02
    anatin um or some kind of chronic
  • 00:29:05
    disease that that is that might be
  • 00:29:07
    impairing cellular energy
  • 00:29:09
    production um so you just you never know
  • 00:29:15
    um who who's going to show up needing
  • 00:29:18
    what again um who would predict that you
  • 00:29:22
    know the the 44 year-old has um better
  • 00:29:26
    omega-3 um status than the
  • 00:29:30
    23-year-old well you can't predict it
  • 00:29:33
    that's why we have to measure we cannot
  • 00:29:35
    accurately in my humble opinion I
  • 00:29:37
    apologize we cannot accurately predict
  • 00:29:40
    need we also know that small things can
  • 00:29:43
    have a large impact so we've got these
  • 00:29:45
    fatty acids that are necessary for
  • 00:29:49
    inflammation production and counter
  • 00:29:51
    inflammation production and protecting
  • 00:29:53
    the brain we know that these um fatty
  • 00:29:57
    acids can be Dam damaged um just through
  • 00:29:59
    a chemical reaction that we call oxidant
  • 00:30:02
    oxidant stress and they become oxidants
  • 00:30:05
    themselves and can go on to cause a
  • 00:30:07
    dysfunction at the cellular level and we
  • 00:30:10
    can measure that in in Te bars or
  • 00:30:12
    oxident stress
  • 00:30:14
    markers but who what what of your
  • 00:30:17
    patients or even many doctors these days
  • 00:30:19
    would see the connection or predict the
  • 00:30:22
    connection between say cardiovascular
  • 00:30:25
    disease and psychiatric disease heart
  • 00:30:27
    function brain function and who would
  • 00:30:30
    think that that Central connection might
  • 00:30:33
    just be in the fatty acid systems here
  • 00:30:37
    and the are we running around with
  • 00:30:39
    damaged fatty acid systems or healthy
  • 00:30:42
    and balanced fatty acid
  • 00:30:44
    systems so the neutral can become a
  • 00:30:47
    really great tool to help you show your
  • 00:30:51
    clients results such as mother and
  • 00:30:54
    daughter here interesting the the type
  • 00:30:57
    of
  • 00:30:58
    nutritional needs that they have but
  • 00:31:00
    some differences similar
  • 00:31:02
    diet you can um show them in nice
  • 00:31:05
    graphic form and help them understand
  • 00:31:07
    what kind of nutritional needs they're
  • 00:31:09
    recommending and why just taking um you
  • 00:31:12
    know an over-the-counter multivitamin is
  • 00:31:14
    probably not going to do what they need
  • 00:31:15
    to
  • 00:31:16
    do I promise not to get in the Weeds on
  • 00:31:19
    this and in fact we've got about 10 15
  • 00:31:21
    more minutes before we're going to go to
  • 00:31:22
    some questions then let you get back to
  • 00:31:24
    your practice but
  • 00:31:26
    um uh again
  • 00:31:29
    um one of the one of the useful um I
  • 00:31:34
    would say one of the most useful
  • 00:31:36
    purposes of advanced testing is really
  • 00:31:39
    to have evidence that's indisputable so
  • 00:31:42
    that your client will believe and when
  • 00:31:45
    we believe we take action uh and all
  • 00:31:48
    that behavioral study that I did and
  • 00:31:50
    work with um corporations on population
  • 00:31:54
    Health that's what I discovered people
  • 00:31:57
    believe when they see and experience it
  • 00:32:00
    for
  • 00:32:01
    themselves you may not KN this know this
  • 00:32:03
    but um neutraal looks at other metabolic
  • 00:32:06
    markers and I'm just going to focus on
  • 00:32:08
    one here right now um around the
  • 00:32:11
    gut gut's the place to start with most
  • 00:32:14
    problems and you can actually use the
  • 00:32:16
    neutraal not only to architect a
  • 00:32:18
    patients U nutritional Therapy Program
  • 00:32:22
    but also uh help determine whether they
  • 00:32:24
    may have some gut dysbiotic issues that
  • 00:32:28
    that you could treat uh empirically
  • 00:32:30
    through you know giving them fermented
  • 00:32:31
    foods or prebiotics or probiotics or um
  • 00:32:36
    cause you to move to maybe more advanced
  • 00:32:38
    gut test like the cdsa ETC stool testing
  • 00:32:42
    you know looking at what's really
  • 00:32:43
    growing in the gut there's also you know
  • 00:32:45
    vitamin markers and um detoxification
  • 00:32:49
    markers
  • 00:32:51
    here all
  • 00:32:53
    right let me see oh yeah I thought this
  • 00:32:56
    was interesting too um I if I'm
  • 00:32:59
    recalling I think this daughter was
  • 00:33:01
    around 14 or
  • 00:33:03
    15 um I find it's interesting that the
  • 00:33:07
    the mother um you know again has um uh a
  • 00:33:12
    better omega-3 index and kind of
  • 00:33:15
    cardiovascular risk assessment than her
  • 00:33:17
    daughter I mean who would be predicting
  • 00:33:19
    that um young people would have uh risk
  • 00:33:22
    factors that adults
  • 00:33:24
    do okay so uh where do we start
  • 00:33:28
    um when you know he won't change his
  • 00:33:30
    diet this is the list of excuses that I
  • 00:33:32
    that I've heard a thousand times right
  • 00:33:34
    the wife says he won't change his diet
  • 00:33:36
    oh my dad was a diabetic I guess that
  • 00:33:38
    implies that I I have a reason for mine
  • 00:33:41
    it's genetic my favorite I really don't
  • 00:33:44
    eat that bad
  • 00:33:45
    doctor um I do a lot of cardio and the
  • 00:33:49
    one that I do actually believe which is
  • 00:33:50
    I hardly eat but I can't lose
  • 00:33:55
    weight so in the
  • 00:33:58
    90s the human genome um was uncovered
  • 00:34:02
    and the theory was that we're going to
  • 00:34:04
    find a bunch of common genetic
  • 00:34:06
    variations for the common diseases we
  • 00:34:09
    see and um that proved to be true in
  • 00:34:13
    genomite association studies um with one
  • 00:34:18
    big caveat which was it didn't explain
  • 00:34:22
    very much of the problem so if you look
  • 00:34:25
    at the genetic um the genetic
  • 00:34:28
    contribution to type 2 diabetes it's
  • 00:34:30
    very very small but there's a lot of
  • 00:34:33
    other rare variants rare polymorphisms
  • 00:34:37
    in the genetic code that stacked
  • 00:34:40
    together in certain ratios and ways play
  • 00:34:43
    a role in these the development of these
  • 00:34:45
    chronic diseases so it's really the
  • 00:34:49
    um the the new paradigm is that these
  • 00:34:52
    common variants only represent a
  • 00:34:54
    fraction of disease and really what
  • 00:34:56
    we're dealing with is multivariant
  • 00:34:59
    genetics and
  • 00:35:01
    environment um but there's something
  • 00:35:03
    more I mean it's more complicated than
  • 00:35:05
    that and that's where we move into the
  • 00:35:07
    field um of epigenetics
  • 00:35:10
    and you know since I'm running out of
  • 00:35:12
    time here I I really would would sum up
  • 00:35:15
    epigenetics as the genetic change
  • 00:35:21
    without changing the genetics or the
  • 00:35:25
    regulation of the expression of the
  • 00:35:29
    fixed genetic code or the switching
  • 00:35:33
    mechanisms that are um that are imposed
  • 00:35:38
    upon the genome that cause certain genes
  • 00:35:42
    to be expressed and certain genes to be
  • 00:35:45
    suppressed so this is the study of Gene
  • 00:35:48
    Expressions that are independent of the
  • 00:35:52
    genotype and that are actually heritable
  • 00:35:56
    or can be transmitted to um The
  • 00:36:00
    Offspring if you want some interesting
  • 00:36:02
    reading look at the Dutch hunger famine
  • 00:36:04
    study it's the Dutch hunger famine study
  • 00:36:07
    just go on PubMed put Dutch hunger
  • 00:36:09
    famine study and you will see they've
  • 00:36:12
    studied um the impact um of the F0 F1 F2
  • 00:36:18
    progyny after the Dutch hunger famine
  • 00:36:20
    this was a kind of a sudden onset famine
  • 00:36:23
    and what they discovered was that the
  • 00:36:26
    the epigenetic markers imprinted on the
  • 00:36:30
    fetus and as an example around the par
  • 00:36:33
    Gene Locus or the gene Locus that is
  • 00:36:35
    involved in diabetes the epigenetic
  • 00:36:38
    imprinting on that was different if Mom
  • 00:36:41
    was 28 weeks pregnant when the famine
  • 00:36:43
    struck or if she got pregnant when the
  • 00:36:46
    famine was going and that epigenetic
  • 00:36:49
    imprint is linked to not those fetuses
  • 00:36:53
    getting diabetes but their children
  • 00:36:55
    getting diabetes
  • 00:36:57
    there are also some fascinating epig
  • 00:37:00
    genetic studies around childhood trauma
  • 00:37:02
    or maternal psychological trauma and the
  • 00:37:06
    epigenetic or methylation fingerprint um
  • 00:37:09
    on the cortisol receptor areas of the
  • 00:37:14
    genome and then there's also a a
  • 00:37:17
    mechanism of regulating RNA so back in
  • 00:37:20
    the 90s was when I was doing biology
  • 00:37:22
    there were these um little things called
  • 00:37:24
    micro rnas and they thought they were
  • 00:37:26
    just garbage and now we know that those
  • 00:37:28
    are actually another uh layer of
  • 00:37:31
    epigenetic Regulation uh after uh
  • 00:37:36
    transcription so the way that I see it
  • 00:37:38
    is this is one of the epigenetics is one
  • 00:37:41
    of the things that makes our body
  • 00:37:43
    infinitely adap adaptive to all of these
  • 00:37:45
    things that I call
  • 00:37:47
    inputs financial status that's an
  • 00:37:49
    interesting
  • 00:37:51
    input the thing the the phenotype that
  • 00:37:54
    we're seeing is representative of all
  • 00:37:56
    those in
  • 00:37:58
    and our body is translation of those
  • 00:38:00
    inputs into physiologic processes so I
  • 00:38:03
    really see that we have an infinitely
  • 00:38:04
    adaptive organism and I think you would
  • 00:38:06
    probably agree because isn't it amazing
  • 00:38:08
    that people can go for 20 or 30 years
  • 00:38:11
    without actually drinking water um they
  • 00:38:15
    just drink soda isn't it amazing that um
  • 00:38:19
    they can do repetitive work over and
  • 00:38:21
    over
  • 00:38:22
    again and never really exercise their
  • 00:38:25
    body we can eat almost spiritually no
  • 00:38:28
    whole food yet we still live and
  • 00:38:31
    function fairly well so the body really
  • 00:38:35
    wants to
  • 00:38:36
    heal um by doing some of this Advanced
  • 00:38:39
    testing and giving people insights into
  • 00:38:41
    their comple into the complex nature of
  • 00:38:44
    their puzzle and being able to translate
  • 00:38:47
    that into a simple strategic plan you
  • 00:38:50
    will uncover the robust healing
  • 00:38:52
    properties of that person's body for
  • 00:38:55
    them so they can experience it for
  • 00:38:57
    themselves so they can believe and then
  • 00:38:59
    you'll have changed a
  • 00:39:01
    life so
  • 00:39:04
    um I'm going to wrap up here just a
  • 00:39:07
    couple minutes on some of
  • 00:39:09
    the uh
  • 00:39:11
    genetic
  • 00:39:12
    um uh genetic markers that can be tested
  • 00:39:15
    and again the concept here is
  • 00:39:20
    um when you when you get into testing
  • 00:39:22
    genetics it's a little bit hard it was
  • 00:39:24
    hard for me anyway maybe I'm not that
  • 00:39:26
    sharp I didn't really know what to do
  • 00:39:28
    with the information because I was
  • 00:39:30
    recommending the same things for people
  • 00:39:32
    and this was several years ago I I've
  • 00:39:34
    kind of come full circle back around and
  • 00:39:37
    what I realize is genetic testing can
  • 00:39:41
    help me get the client focused on some
  • 00:39:45
    key areas of
  • 00:39:48
    vulnerability but even more effective I
  • 00:39:51
    think is genetic testing can help me not
  • 00:39:55
    focus on things that aren't really
  • 00:39:57
    the highrisk areas so you have the
  • 00:40:00
    benefit of knowing what to take your
  • 00:40:02
    focus off of that's not necessary so you
  • 00:40:04
    can apply the the uh the most
  • 00:40:08
    significant amount of your bandwidth to
  • 00:40:10
    the issues where there's real
  • 00:40:13
    vulnerability I mean because the fact is
  • 00:40:15
    is that um everybody should address diet
  • 00:40:20
    reduce stress not smoke and do physical
  • 00:40:23
    activity regardless of what your
  • 00:40:25
    genotype is however if you have a
  • 00:40:28
    genotype um sorry
  • 00:40:32
    here if you have a genotype that
  • 00:40:34
    predisposes you to let's just say um LDL
  • 00:40:38
    cholesterol metabolic problems it it
  • 00:40:40
    would probably cause us to focus our
  • 00:40:43
    therapeutic regimen and diet in a more
  • 00:40:46
    intense way um and so I might I might
  • 00:40:51
    push this person harder to do say
  • 00:40:54
    interval therapy I might ride them
  • 00:40:57
    harder to reduce the smoking or get the
  • 00:41:00
    animal fats out of their diet or um uh
  • 00:41:03
    increase their fishal as higher that I
  • 00:41:05
    might otherwise I also might follow some
  • 00:41:08
    of these oxidative markers to prove that
  • 00:41:11
    what they're doing in the lifestyle
  • 00:41:14
    piece and what I'm doing in the
  • 00:41:15
    nutritional piece is actually reducing
  • 00:41:17
    some of the oxidant stress burden
  • 00:41:20
    improving their omega-3 fatty acids
  • 00:41:22
    balance as just a couple of
  • 00:41:25
    examples you know looking at that uh
  • 00:41:27
    someone's predisposition for um say
  • 00:41:31
    excessive release of cyto kindes um like
  • 00:41:34
    torosis Factor can be useful um in terms
  • 00:41:40
    of for instance you know I I can eat a a
  • 00:41:43
    fairly varied diet um I don't really
  • 00:41:46
    change my body habit as much but it
  • 00:41:48
    impacts my brain um everybody is going
  • 00:41:52
    to be different and if you know someone
  • 00:41:53
    has a a u genetic predisposition to
  • 00:41:57
    Having excess releases of cyto kindes
  • 00:42:00
    and then the downstream inflammatory and
  • 00:42:02
    oxidant stress of that you may change
  • 00:42:04
    your nutritional regimen you may educate
  • 00:42:07
    them in a different way you may screen
  • 00:42:08
    them over the years in a different way
  • 00:42:11
    um in terms of cardiovascular disease
  • 00:42:13
    risk Etc you might go ahead and get that
  • 00:42:15
    crowded Doppler now even though maybe
  • 00:42:18
    there's really no traditional risk
  • 00:42:21
    indicator for
  • 00:42:25
    that and you know something that I'm
  • 00:42:28
    really into is this behavioral piece and
  • 00:42:30
    I've been fascinated about that for a
  • 00:42:31
    while and I see Behavior really as as an
  • 00:42:35
    outcome of the function of the organ
  • 00:42:37
    that we call the brain um the
  • 00:42:40
    interesting thing is we can observe that
  • 00:42:41
    organ working um and we can modify it
  • 00:42:45
    with our own thinking processes and our
  • 00:42:46
    own choices but um the way that organ is
  • 00:42:51
    working the the way the cells in that
  • 00:42:53
    organ work are following the same rules
  • 00:42:55
    of physiology and metabolism
  • 00:42:58
    that every other cell in the body and
  • 00:43:00
    the other organs are following so
  • 00:43:02
    everything is sort of playing by the
  • 00:43:03
    their own rules maybe with a little bit
  • 00:43:05
    of a different
  • 00:43:07
    um a little bit of some different
  • 00:43:09
    processes involved
  • 00:43:12
    so let's go to a couple cases here um
  • 00:43:16
    and then I I literally have two more
  • 00:43:17
    minutes so H how do you help someone
  • 00:43:21
    move from triglycerides of 500 to 180 an
  • 00:43:24
    A1C of 6.8 to 5.8
  • 00:43:28
    these are great markers um over time
  • 00:43:31
    here losing nearly 100 pounds um well
  • 00:43:35
    you've got to do the basics first right
  • 00:43:38
    like vitamins don't solve this problem
  • 00:43:40
    and testing doesn't solve this problem
  • 00:43:42
    but first of all you you have the
  • 00:43:44
    testing to to show hey this is the
  • 00:43:46
    current state um it's the it's answering
  • 00:43:49
    the how do we know question and then you
  • 00:43:52
    can follow them over
  • 00:43:54
    time um using data to develop more
  • 00:43:58
    specific nutritional regimens knowing
  • 00:44:01
    what areas to focus on or maybe don't
  • 00:44:03
    need to be focused on as much um and
  • 00:44:06
    then giving them a more valid assessment
  • 00:44:09
    of cardiovascular risk because you're
  • 00:44:12
    using um multiple different modalities
  • 00:44:15
    to look at the same uh
  • 00:44:18
    problem and I did this on the population
  • 00:44:21
    level as well and this just shows you
  • 00:44:24
    the results of a a whole food
  • 00:44:25
    plant-based 12we diet and as an example
  • 00:44:29
    here you know 68% of the population was
  • 00:44:33
    able um to see a almost an 18%
  • 00:44:35
    Improvement in LDL over 12 weeks using
  • 00:44:39
    um a vitamin packet a pharmaceutical
  • 00:44:41
    grade vitamin packet and um a whole food
  • 00:44:45
    plant-based diet and actually I'll tell
  • 00:44:47
    you this is um this result is as good or
  • 00:44:52
    better than some year-long studies um
  • 00:44:54
    that are out there in in the uh
  • 00:44:56
    literature so all right I think we can
  • 00:44:59
    open up for uh some questions now if
  • 00:45:01
    you'd like all right great thank you so
  • 00:45:04
    much Dr right that was a wonderful
  • 00:45:07
    presentation um and we have received
  • 00:45:09
    some great feedback I do want to remind
  • 00:45:12
    everyone that the PowerPoint will be
  • 00:45:13
    available on our website in PDF format
  • 00:45:16
    next week um so let's start with the
  • 00:45:19
    first question on that chart that you
  • 00:45:22
    had of the animal-based foods or the the
  • 00:45:26
    carbohydrate Foods there were some
  • 00:45:28
    animal based foods that were at the
  • 00:45:29
    bottom and the question was are they
  • 00:45:32
    inflammatory or non-inflammatory okay
  • 00:45:35
    let me go high level let's just talk
  • 00:45:37
    about accident stress so I'm not um I
  • 00:45:40
    eat about anything um I don't drink
  • 00:45:43
    sugar uh once in a while I'll you know I
  • 00:45:46
    have a Starbucks latte or whatever
  • 00:45:48
    um the the concept is this is what I
  • 00:45:52
    found useful for my clients people get
  • 00:45:55
    into their belief systems about food and
  • 00:45:57
    diets and you cannot change those belief
  • 00:46:00
    systems Le I I've known it's fruitless
  • 00:46:04
    so instead what I do is I say eat what
  • 00:46:06
    you want but understand this concept
  • 00:46:09
    meat is neither good nor bad neither
  • 00:46:12
    here nor there but what you should
  • 00:46:14
    understand is this if you take a pound
  • 00:46:17
    of animal products whether it's eggs or
  • 00:46:21
    beef or pork or whatever and you measure
  • 00:46:26
    the amount of o accident chemicals in
  • 00:46:28
    that raw Animal product versus a pound
  • 00:46:31
    of green leafy vegetables there's
  • 00:46:34
    probably a hundredfold difference um
  • 00:46:37
    then you would consume the vegetable
  • 00:46:40
    products just as they are raw but you
  • 00:46:42
    don't consume raw beef or meat you do
  • 00:46:46
    something to it now many people perceive
  • 00:46:48
    that grilling for instance um is somehow
  • 00:46:51
    healthier because the fat drips down out
  • 00:46:54
    of the
  • 00:46:54
    meat well actually what you're doing is
  • 00:46:57
    you're superheating the food you're
  • 00:46:59
    charring the food you're creating
  • 00:47:00
    chemical reactions between sugar and
  • 00:47:02
    proteins called a maard or Browning
  • 00:47:05
    reaction and you're actually increasing
  • 00:47:07
    the oxidant stress composition of that
  • 00:47:10
    food by another 100 fold so you know
  • 00:47:14
    it's been about three years since I
  • 00:47:16
    looked at this but but um there was a
  • 00:47:19
    one of the nutritional societies
  • 00:47:22
    actually studied the oxidant stress in a
  • 00:47:24
    couple hundred common foods that we eat
  • 00:47:27
    I was very disappointed to find that
  • 00:47:28
    Pepsi has very very low oxident stress
  • 00:47:30
    as an example um but uh I remember one
  • 00:47:34
    of their um one of their examples was
  • 00:47:37
    let's just call it 6 ounces of beef I'm
  • 00:47:39
    going to get the numbers kind of wrong
  • 00:47:41
    here so don't don't hold me to this but
  • 00:47:43
    you get the concept you you take six or
  • 00:47:46
    eight ounces of beef and let's just say
  • 00:47:47
    it has a 100 units of oxidant stress I
  • 00:47:50
    don't know if they me I don't know how
  • 00:47:52
    they exactly measure that I can't
  • 00:47:53
    remember um then they superheated that
  • 00:47:56
    be be and U measured the accident stress
  • 00:47:59
    and it was something like 7 or
  • 00:48:01
    8,000 um and they they grilled it or I
  • 00:48:04
    think in that case they pan fried it so
  • 00:48:08
    um what I go back to is the closer it
  • 00:48:12
    resembles something in nature the closer
  • 00:48:14
    it is to what shows up in nature the
  • 00:48:17
    less you have to think about its impact
  • 00:48:20
    on your
  • 00:48:24
    body great thank you I agree with
  • 00:48:28
    that um the next
  • 00:48:31
    question is you were talking about how
  • 00:48:34
    the gut is kind of where inflammation
  • 00:48:37
    starts um how do you address the gut
  • 00:48:41
    being that that's the start of
  • 00:48:44
    inflammation okay so you have two things
  • 00:48:47
    to do in
  • 00:48:50
    tandem um or maybe not may you could do
  • 00:48:53
    them in tanm or you could do them
  • 00:48:54
    sequentially it's all going to be
  • 00:48:56
    depending on your ability to manage
  • 00:48:59
    multiple variables with your client and
  • 00:49:01
    your client's ability to manage multiple
  • 00:49:03
    variables um for me where I'm at after
  • 00:49:06
    doing this for seven years I can I can
  • 00:49:08
    manage uh multiple variables and I can
  • 00:49:11
    really tailor it to what I think my
  • 00:49:13
    clients needs are and then if I discover
  • 00:49:15
    I gave them more variables to manage
  • 00:49:18
    than they can then I I know how to back
  • 00:49:21
    it out um one thing I found when I began
  • 00:49:24
    doing this was that I had a lot of
  • 00:49:25
    people that didn't come back and what I
  • 00:49:27
    discovered was is I simply overwhelmed
  • 00:49:29
    them with the number of things to do so
  • 00:49:32
    here's where we start eliminate and add
  • 00:49:36
    elimination in anybody walking in off
  • 00:49:39
    the
  • 00:49:39
    street in my humble opinion elimination
  • 00:49:43
    is if you can only start in one place
  • 00:49:45
    elimination is the place to start and I
  • 00:49:48
    focus on um what I call the frightening
  • 00:49:50
    for Foods so reducing and eliminating as
  • 00:49:55
    much of these four categories of foods
  • 00:49:58
    as possible is a place to start and they
  • 00:50:01
    are um
  • 00:50:04
    sugar this is not rocket science by the
  • 00:50:06
    way okay but but the awesome thing about
  • 00:50:08
    functional and metabolic medicine is
  • 00:50:10
    none of it's rocket science um it's
  • 00:50:14
    these things are evident so it's sugar
  • 00:50:16
    flour because that's almost sugar right
  • 00:50:19
    and it has gluten uh
  • 00:50:22
    fructose and oil M now everybody says
  • 00:50:26
    what about olive oil and I just don't
  • 00:50:28
    even answer it I say okay that's not the
  • 00:50:31
    the concept is neither sugar nor flour
  • 00:50:34
    nor fructose nor oils show up in
  • 00:50:38
    nature these are macronutrient extracts
  • 00:50:41
    of food they will disrupt the natural
  • 00:50:47
    gut
  • 00:50:49
    microbiome and so that's how I start
  • 00:50:53
    with the
  • 00:50:54
    gut um
  • 00:50:57
    what I'll often have them do very
  • 00:50:59
    practically speaking is after I've
  • 00:51:00
    educated them around that I'll have them
  • 00:51:02
    do a food journal and at the end of a
  • 00:51:04
    week I just asked them to Circle in red
  • 00:51:07
    any foods that they've eaten that
  • 00:51:09
    contain any of those four components and
  • 00:51:13
    then just look high level gastal at are
  • 00:51:16
    there a lot of red circles or very few
  • 00:51:19
    and then begin to reduce that week over
  • 00:51:22
    week then you get to the point well what
  • 00:51:25
    do I eat doctor I can't eat anything
  • 00:51:26
    doctor well there's actually lots of
  • 00:51:28
    people in the world not eating anything
  • 00:51:30
    that you eat every day and they're doing
  • 00:51:31
    just fine and so you know um that's
  • 00:51:34
    where you begin to develop the
  • 00:51:35
    behavioral stuff and I have to tell you
  • 00:51:38
    even as quote the
  • 00:51:40
    expert I struggle with figuring out what
  • 00:51:43
    to eat I'm kind of stuck in a diet rut
  • 00:51:46
    myself um and so I'm thinking about
  • 00:51:49
    hiring nutritionists just to come in and
  • 00:51:51
    tell me what I already know but give me
  • 00:51:53
    some details that I can act on so I can
  • 00:51:55
    begin to change the habits architect the
  • 00:51:57
    environment
  • 00:51:59
    differently good all right thanks um and
  • 00:52:04
    so one of the four things you said you
  • 00:52:06
    have people eliminate is fructose and
  • 00:52:08
    then you were talking about fructose
  • 00:52:11
    earlier and how it can um interfere with
  • 00:52:14
    energy production with the KB cycle um
  • 00:52:18
    the question was around is that fructose
  • 00:52:20
    from fruits and juice or is it also high
  • 00:52:23
    fructose corn syrup or everything right
  • 00:52:27
    so um let me answer that in a concept
  • 00:52:30
    way um in in some ways because I I hear
  • 00:52:35
    that question a lot as well from
  • 00:52:36
    patients as well as other doctors when I
  • 00:52:38
    teach this stuff in some ways it really
  • 00:52:40
    doesn't matter because it would be
  • 00:52:43
    virtually impossible for a human being
  • 00:52:45
    to consume enough fructose from raw
  • 00:52:48
    fruit to impact the cellular energy um
  • 00:52:53
    mechan metabolics um
  • 00:52:57
    you know you can drink a soda that has
  • 00:53:00
    68 you know or whatever grams of of
  • 00:53:05
    sugar in it that's all
  • 00:53:07
    fructose fructose extracted from corn um
  • 00:53:11
    and you can do that in 7 to 15 minutes
  • 00:53:15
    and you can do that five times a day and
  • 00:53:18
    not even think anything of it
  • 00:53:21
    so if I were asked that question by a
  • 00:53:24
    patient I would raise their thinking to
  • 00:53:27
    a very practical level which is um Step
  • 00:53:31
    One let's let's
  • 00:53:36
    just you I'm not worried about you over
  • 00:53:39
    consuming fruit whole fruit whole raw
  • 00:53:42
    fruit um but from a purely scientific
  • 00:53:45
    standpoint I've never read anything I
  • 00:53:48
    could be somewhat wrong here uh but
  • 00:53:50
    practically speaking I don't run into
  • 00:53:52
    sick people coming in with um with
  • 00:53:54
    mitochondrial energy chronic fatigue
  • 00:53:57
    issues ETC that are on a whole food
  • 00:53:59
    plant-based diet I just never see it
  • 00:54:01
    unless maybe they have um they've had
  • 00:54:04
    something you know their health went
  • 00:54:06
    into the the pit of despair um because
  • 00:54:09
    of you know like in my family lamb
  • 00:54:11
    disease or because they were chronically
  • 00:54:13
    ill from a you know couple decades of a
  • 00:54:15
    poor diet
  • 00:54:17
    so right okay um and then another
  • 00:54:22
    question about what are your thoughts on
  • 00:54:25
    the acid alkaline
  • 00:54:28
    diet this is a trend I just had two of
  • 00:54:31
    those questions from clients yesterday
  • 00:54:34
    um okay this is my opinion because I
  • 00:54:37
    have not gone out and deeply sought this
  • 00:54:42
    information um so uh gosh I don't even
  • 00:54:46
    know if if goova has a Blog on there it'
  • 00:54:48
    be interesting to see what people um
  • 00:54:50
    what evidence uh the audience may have
  • 00:54:53
    for um for or against what I'm saying
  • 00:54:55
    but very practically speaking um we know
  • 00:55:00
    that um nearly dead people or dead
  • 00:55:04
    people are pretty
  • 00:55:06
    acidic we also know that the body will
  • 00:55:10
    do whatever is necessary to maintain
  • 00:55:14
    homeostasis one of those things is a
  • 00:55:16
    fairly tight uh blood and cellular
  • 00:55:21
    pH I think the more that we eat a
  • 00:55:24
    processed food diet the the the more we
  • 00:55:27
    push our um our cells to adapt in ways
  • 00:55:33
    that will lead to dysfunction long term
  • 00:55:35
    and then create these things we call
  • 00:55:37
    diseases but in terms of manipulating
  • 00:55:41
    the alkalinity of say your water um I
  • 00:55:46
    would be more concerned that that would
  • 00:55:48
    cause a disruption of your body's
  • 00:55:49
    natural
  • 00:55:51
    homeostasis and then the the answer I
  • 00:55:53
    usually get is um about you know people
  • 00:55:57
    um say treating cancer with vegetables
  • 00:56:01
    to reduce or reduce the body's acidity
  • 00:56:04
    and the argument that I would make there
  • 00:56:06
    is um everybody should be on lots of
  • 00:56:09
    vegetables and um and the people that
  • 00:56:13
    make that argument about alkalinity they
  • 00:56:15
    don't balance it with the fact that
  • 00:56:17
    people are getting tons of plant
  • 00:56:19
    nutrients the phytonutrients the um the
  • 00:56:22
    kakin you know those those plant um
  • 00:56:25
    those plant pigments that go into our
  • 00:56:27
    body and and act as
  • 00:56:34
    Neutrogena side dismutase enzymes
  • 00:56:36
    stimulate Nrf2 Gene to you know turn on
  • 00:56:39
    the antioxidant enzymes so that's my
  • 00:56:43
    current going kind of perspective on
  • 00:56:45
    that but um I would love it if anyone
  • 00:56:48
    has some scientific research that
  • 00:56:50
    they're familiar with um send that on
  • 00:56:52
    over to to Christine and and get it to
  • 00:56:55
    me I I could use the
  • 00:56:58
    education all right thank you Dr R we we
  • 00:57:01
    really appreciate it in the interest of
  • 00:57:03
    time we'll have to end our question and
  • 00:57:05
    answer period there um so for additional
  • 00:57:10
    education materials we'd like to
  • 00:57:12
    encourage you all to visit our website
  • 00:57:14
    www. gdx.net on this site you'll find
  • 00:57:18
    sample reports kit instructions and
  • 00:57:21
    other information for all of our
  • 00:57:23
    profiles after taking advantage of the
  • 00:57:26
    materials found on our website feel free
  • 00:57:28
    to contact client services with your
  • 00:57:30
    questions there's a number on the slide
  • 00:57:32
    for us and UK customer service
  • 00:57:35
    Additionally you can call client
  • 00:57:37
    services if you need assistance in
  • 00:57:38
    setting up a my GDX account we also
  • 00:57:42
    offer complimentary appointments with
  • 00:57:44
    our medical education Specialists to
  • 00:57:46
    answer questions that are related to our
  • 00:57:48
    testing including choosing the right
  • 00:57:50
    test and reviewing patient test results
  • 00:57:54
    and then finally we'd like to encourage
  • 00:57:55
    you to look for upcoming webinars on our
  • 00:57:57
    website next month we have Dr Dian Minik
  • 00:58:01
    speaking on neutrogenia and clinical
  • 00:58:03
    practice genes food and Specialty
  • 00:58:07
    Diagnostics thanks again Dr Wright for a
  • 00:58:10
    great presentation and thank you all for
  • 00:58:11
    listening in today
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