Artificial Intelligence in Neurological Diagnosis & Management | 18th Neurology Certificate Course
Resumen
TLDRDr. Jeanette's presentation at the neurology certificate course addresses the rapidly evolving intersection of artificial intelligence (AI) and neurology. She emphasizes how AI can significantly impact the diagnosis and treatment of neurological disorders, particularly in stroke care and epilepsy. The lecture highlights the urgent need for healthcare professionals to understand AI as an essential part of their practice. Key topics covered include the acceleration of AI research publications, the importance of high-quality data, and the potential of AI to reduce latency in care delivery, ultimately improving patient outcomes. Dr. Jeanette also discusses how AI can develop new biomarkers for diseases like Alzheimer's disease and stresses the need for continuous learning environments in AI applications within medicine. Overall, she advocates for the integration of AI in clinical settings to enhance decision-making and prediction capabilities while maintaining the crucial role of physicians.
Para llevar
- 🤖 AI is revolutionizing neurology and clinical practice.
- 📈 AI publications are increasing rapidly, led by tech companies.
- 🧠AI can reduce treatment latency in stroke care.
- 🔬 High-quality data is essential for effective AI applications.
- 💡 Understanding AI is now as critical as learning medical biochemistry.
CronologÃa
- 00:00:00 - 00:05:00
Jeanette, a neurocritical care specialist, discusses the role of artificial intelligence (AI) in neurological disorders during the 18th neurology certificate course at Aahan University Hospital. She shares her background and ongoing work in the field, emphasizing the importance of understanding clinically relevant AI concepts.
- 00:05:00 - 00:10:00
AI is rapidly changing healthcare by affecting algorithms that can influence billions of people globally. Jeanette highlights the significant increase in AI publications, particularly in neurology, stressing that academia is lagging behind tech companies like Facebook and Google.
- 00:10:00 - 00:15:00
The rise in AI publications correlates with the availability of high-quality data, particularly in neurodegenerative disorders like Alzheimer's and Parkinson's. Furthermore, Jeanette cites the increasing relevance of AI in stroke care, emphasizing the importance of real-world applications in contrast to academia.
- 00:15:00 - 00:20:00
AI development in healthcare is accelerating due to reduced costs of compute power and faster data storage. Jeanette notes that understanding AI concepts becomes essential for healthcare providers to improve treatment quality and reduce latency in care delivery, especially for conditions like stroke.
- 00:20:00 - 00:25:00
Jeanette emphasizes that it is crucial to understand AI as a technology enabler rather than just a tool. She stresses the need for medical professionals to learn about AI, likening its importance to foundational medical knowledge and asserting that its application will impact patient care significantly.
- 00:25:00 - 00:30:00
There are fundamental differences in reasoning methods between AI and traditional methods. AI, particularly machine learning and deep learning, relies on patterns and examples rather than rules and instructions, leading to more efficient hypotheses and discoveries in clinical practice.
- 00:30:00 - 00:35:00
Statistics and machine learning serve different purposes; statistics identify relationships while AI focuses on predictions. Jeanette underscores the shift from reactive disease management to proactive prediction and prevention through AI applications in healthcare.
- 00:35:00 - 00:42:04
Artificial intelligence is a critical tool that, while not replacing physicians, will aid in augmenting their capabilities. Jeanette forecasts a future where physicians using AI will outperform those who do not, advocating for an integration of AI in daily medical practices.
Mapa mental
VÃdeo de preguntas y respuestas
What is the main focus of Dr. Jeanette's presentation?
The focus is on the impact of artificial intelligence in neurology, specifically for stroke and epilepsy.
How has the interest in AI publications changed recently?
Publications in AI have been increasing rapidly, particularly from technology companies like Facebook and Google.
What are the two major applications of AI in neurology discussed?
Stroke management and the development of biomarkers for diseases like Alzheimer's.
Why is AI considered a technology enabler?
AI is seen as a general purpose technology that can be applied across various fields, not limited to one specific area.
How does AI help reduce latency in stroke care?
AI applications in stroke care can decrease the time to treatment, potentially saving lives and reducing disability.
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- 00:00:00hi this is jeanette neurocritical care
- 00:00:01stroke and epilepsy specialist today i'm
- 00:00:03going to be presenting an artificial
- 00:00:04intelligence and neurological disorders
- 00:00:06i'm very grateful to be invited to speak
- 00:00:09on the prestigious course which is the
- 00:00:1118th neurology certificate course from
- 00:00:14aahan university hospital being medical
- 00:00:17advisor consultation for many different
- 00:00:19companies and on artificial intelligence
- 00:00:21that i can't list over here but these
- 00:00:22are generally where my current positions
- 00:00:25are in terms of
- 00:00:27employment and contraction and some of
- 00:00:29the independent work that i'm doing in
- 00:00:31the field itself
- 00:00:32now this is a very big topic and i
- 00:00:35cannot boil an ocean
- 00:00:37what that term means is basically that
- 00:00:38this is a vast ocean in which we have to
- 00:00:40get into so the objective is basically
- 00:00:43to get as much information as you need
- 00:00:45in terms of clinically relevant
- 00:00:47artificial intelligence and getting the
- 00:00:49basic concepts around it and then you
- 00:00:51will improve upon it more and more your
- 00:00:53knowledge in terms of looking at our
- 00:00:55artificial intelligence articles youtube
- 00:00:57videos etc and going from there my
- 00:01:00articles my videos are more and more
- 00:01:02going to be concentrating on artificial
- 00:01:04intelligence so make sure you follow
- 00:01:06me in terms of my youtube channel my
- 00:01:09blog and of course neurology pocketbook
- 00:01:11as well
- 00:01:12so here's the issue
- 00:01:14change was always changing right it's
- 00:01:16never been that issue right i mean at
- 00:01:18the end of the day the
- 00:01:20acceleration of change itself has been
- 00:01:22accelerating for the past decade what
- 00:01:24artificial intelligence is that it
- 00:01:26changed from logarithmic to algorithmic
- 00:01:29change what's the difference the
- 00:01:30difference is that if there's an
- 00:01:32algorithmic change let's say in terms of
- 00:01:33youtube algorithm it affects two billion
- 00:01:36people tick tock three billion people
- 00:01:38facebook three and a half billion people
- 00:01:39it's ridiculous the amount of change
- 00:01:42that you can produce when you change an
- 00:01:44algorithm i mean we always have heard
- 00:01:46this right i mean
- 00:01:50this has been an alumni balls code that
- 00:01:52we keep quoting in pakistan especially
- 00:01:55for a long long time but believe it or
- 00:01:58not the change itself has changed
- 00:02:01interestingly this uh 1922 22 exactly a
- 00:02:05hundred years ago allama iqbal was given
- 00:02:07the title of sir so interestingly we
- 00:02:09have been a 100 year journey and we are
- 00:02:12still talking about changes change and
- 00:02:14believe it or not this time it's very
- 00:02:16significant
- 00:02:18now publications in artificial
- 00:02:20intelligence have been increasing at an
- 00:02:21alarming rate as a matter of fact the
- 00:02:23peer-reviewed applications there were
- 00:02:25publications that were coming in
- 00:02:26artificial intelligence is on a rise
- 00:02:28constantly and more importantly start
- 00:02:30just coming from the academics believe
- 00:02:32it or not more and more publications
- 00:02:34that i read personally are coming from
- 00:02:36facebook and google because those are
- 00:02:38the technology papers that i have to
- 00:02:39make myself aware of because more and
- 00:02:41more changes that these companies are
- 00:02:43coming up with and they are doing real
- 00:02:46good publication and sometimes it's open
- 00:02:48source open access so first of all i
- 00:02:50need to know them personally but just
- 00:02:52letting you know that academia is truly
- 00:02:54falling behind in terms of
- 00:02:56research publications and artificial
- 00:02:58intelligence so if you want to follow
- 00:03:00that technological curve you need to
- 00:03:02follow corporate publications as well as
- 00:03:04academic publications as well
- 00:03:06as far as neurology is concerned as you
- 00:03:08can see every single year there is more
- 00:03:10and more increase in terms of
- 00:03:11publications and neurology these are
- 00:03:13only specific clinical application
- 00:03:15neurology publications that we are
- 00:03:16talking about and you can see that from
- 00:03:182018 to 2020 there is clearly doubling
- 00:03:21every year in terms of publications and
- 00:03:23neurology is concerned all the other
- 00:03:25places as far as you know
- 00:03:28sub-specialties are concerned there has
- 00:03:30been publications general publications
- 00:03:32radiology is one of the top
- 00:03:34publications where you would see
- 00:03:36artificial intelligence being applied to
- 00:03:39however cardiology and neurology are
- 00:03:40neck to neck and if you see covet 19 of
- 00:03:43course was a little higher in terms of
- 00:03:45publications which is probably going to
- 00:03:47fall off now given that we are going
- 00:03:50over the hump of that so artificial
- 00:03:52intelligence application has been used
- 00:03:54in every freaking sub-specialty and
- 00:03:57neurology is not behind as a matter of
- 00:03:59fact neurology is right up at the level
- 00:04:01of cardiology in terms of publications
- 00:04:03as well
- 00:04:04now the publications are divided into
- 00:04:06five major categories and the issue here
- 00:04:09is that the why is that those areas
- 00:04:12being concentrated on it has nothing to
- 00:04:14do with clinical application it has
- 00:04:16everything to do with the availability
- 00:04:18of high quality data
- 00:04:20look alzheimer's parkinson's which are
- 00:04:23the neurodegenerative and dementia
- 00:04:25disorders have had multiple years of
- 00:04:27funding from the government in terms of
- 00:04:29fda nih and ihss and inds all these
- 00:04:33major federal funding has been going
- 00:04:35into dementia because alzheimer's has
- 00:04:37been a big problem when we need newer
- 00:04:39newer solutions
- 00:04:41all those data that has been collected
- 00:04:42in last 10 years from imaging biomarkers
- 00:04:45everything can be churned up through
- 00:04:47artificial intelligence better faster
- 00:04:49because we have availability of high
- 00:04:50quality data however the application the
- 00:04:54true world application in artificial
- 00:04:56intelligence is in stroke that's we're
- 00:04:58going to come into in the next few
- 00:05:00slides so you have to distinguish
- 00:05:01between publications in terms of what
- 00:05:04academia is moving towards and real life
- 00:05:06applications so the reasoning behind it
- 00:05:09is not just the publications itself the
- 00:05:10reasoning behind it is basically
- 00:05:12availability of high quality data
- 00:05:14so
- 00:05:16what it tells me everything is that ai
- 00:05:18is developing super fast as a matter of
- 00:05:20fact when you're going to look at it in
- 00:05:21terms of both technological aspects and
- 00:05:23in terms of clinical applications we are
- 00:05:26seeing more and more applications that
- 00:05:28are getting fda
- 00:05:29i'm not going to use the word approval
- 00:05:31so that's another big thing because fda
- 00:05:33granted fda access fda listed and fda
- 00:05:36approved however for now we're going to
- 00:05:38see that ai is developing fast its
- 00:05:41adoption has become faster as a matter
- 00:05:43of fact more and more industry leaders
- 00:05:45and more and more experts are
- 00:05:48proposing that especially in healthcare
- 00:05:50artificial intelligence should be the
- 00:05:52way to go especially with hims22 if you
- 00:05:54look at the news that came from there
- 00:05:56more and more leaders are going to be
- 00:05:58open to adopting artificial intelligence
- 00:06:01now why now i think there are multiple
- 00:06:03reasons and this is a whole chart and we
- 00:06:05can go into but given the time i'm going
- 00:06:08to just talk about two things number one
- 00:06:10is
- 00:06:10the key issue is compute power it has
- 00:06:13become significantly cheaper and it's
- 00:06:16significantly accessible in terms of
- 00:06:18compute power because we can do compute
- 00:06:20over the cloud and even our devices are
- 00:06:22getting much and much powerful in terms
- 00:06:24of compute second big thing is data and
- 00:06:26not just data in terms of slow hard
- 00:06:29drive spinning drives data hard
- 00:06:32solid state drive which is the flash
- 00:06:34drives and the reason behind is that we
- 00:06:36need faster drives sometimes so that the
- 00:06:39data can go in and out pretty fast
- 00:06:41within the computer engines that is
- 00:06:43decreasing in cost so two major storage
- 00:06:45and compute power is decreasing in cost
- 00:06:47significantly so the accessibility for
- 00:06:50the barrier to entry has gone
- 00:06:51significantly low for these studies to
- 00:06:53come up and therefore more and more
- 00:06:55studies are being done and more and more
- 00:06:57applications are being done on
- 00:06:59artificial intelligence before we get
- 00:07:01into it i always always remember that we
- 00:07:03need to talk about why is it important
- 00:07:06you know you can already apply
- 00:07:07artificial intelligence in any data
- 00:07:09right i mean let's say i'm gonna do uh
- 00:07:11pull out some of the tweet data from
- 00:07:13myself and then put artificial
- 00:07:15intelligence great right i mean we can
- 00:07:16do that but the more important thing is
- 00:07:18to always find out why we want to do
- 00:07:20something especially in terms of
- 00:07:22technological applications so the key
- 00:07:25issue with a neurology is what
- 00:07:27latency of care time is brain so one of
- 00:07:30the things that we want to apply
- 00:07:31artificial intelligence in situations
- 00:07:33where we can decrease the time for
- 00:07:35treatment stroke hemorrhage subarachnoid
- 00:07:38hemorrhage etc the second big issue is
- 00:07:40that we don't have a troponin like i
- 00:07:41mean that would be fantastic right if
- 00:07:43you can get a blood test for alzheimer's
- 00:07:45we can't if you had that that would be
- 00:07:47that would solve so many issues because
- 00:07:48we can have early detection of
- 00:07:50alzheimer's and then early intervention
- 00:07:52of the alzheimer's we can't do that so
- 00:07:54we need new
- 00:07:55significantly new biomarkers in terms of
- 00:07:58imaging in terms of mci clinical
- 00:08:00biomarkers and in terms of genetic
- 00:08:02biomarkers and meaning we probably need
- 00:08:03to combine them so the question is that
- 00:08:05we need to make sure that we have new
- 00:08:07forms of biomarkers that could only be
- 00:08:10achieved by large data
- 00:08:12churned by artificial intelligence we're
- 00:08:14going to continue to have lack of
- 00:08:15neurologist i mean pakistan has a
- 00:08:17significant lack of neurologist then on
- 00:08:19top of that we also have a long tail of
- 00:08:21these patients that are chronically
- 00:08:22going to live with neurological
- 00:08:24disorders either parkinson's alzheimer's
- 00:08:27stroke etc epilepsy all of these things
- 00:08:29we're going to significantly see a
- 00:08:31growing population of older and older
- 00:08:33people around the world and they are all
- 00:08:36going to get you know basically
- 00:08:39neurological problems and we need to
- 00:08:40help them and this is what i keep
- 00:08:42telling cardiology of my cardiology
- 00:08:44folks is that thank you for making sure
- 00:08:46that people are alive so i can take care
- 00:08:47of their neurological problems because
- 00:08:49that was the last
- 00:08:50century to be honest with you where
- 00:08:52cardiology was at the boom in which
- 00:08:54heart problems were the issue when
- 00:08:55people were constantly getting heart
- 00:08:57attacks and dying from it but in their
- 00:08:58lot now they're living well
- 00:09:01and unfortunately being afflicted by
- 00:09:03neurological disorders
- 00:09:05now before i get into the direct
- 00:09:07applications of neurology let me just
- 00:09:09give you some conceptual basics of
- 00:09:10artificial intelligence first and
- 00:09:12foremost you need to understand that
- 00:09:13artificial intelligence is not a
- 00:09:15technology it's a technology enabler
- 00:09:18what that means is that any type of data
- 00:09:20that you're going to generate in either
- 00:09:22through blockchain dna sequences
- 00:09:25internet of things healthcare iot
- 00:09:27autonomous mobiles robotics any
- 00:09:29situation in which you're going to
- 00:09:31generate data and you need to have run
- 00:09:33assimilations of multiple possibilities
- 00:09:36you're going to need artificial
- 00:09:37intelligence
- 00:09:38so this is considered what we call
- 00:09:40general purpose technology it is not
- 00:09:42considered one technology so therefore
- 00:09:45when you have a technology like general
- 00:09:46purpose technology like artificial
- 00:09:48intelligence you do not compare it with
- 00:09:50just dna sequences because that's one
- 00:09:53part of technology that cannot be
- 00:09:54applied in finance but artificial
- 00:09:57intelligence can be applied in finance
- 00:09:59healthcare economics education
- 00:10:01everything so therefore artificial
- 00:10:03intelligence is to be compared with
- 00:10:05electricity so its artificial
- 00:10:07intelligence is as important as
- 00:10:09electricity in terms of its impact
- 00:10:12because it's a general purpose
- 00:10:14technology and that's why there's such a
- 00:10:16huge buzz and everything i mean there's
- 00:10:18a lot of buzz so don't get into it but
- 00:10:19at the end of the day that's where the
- 00:10:21real difference is in terms of just
- 00:10:24being a technology or being a technology
- 00:10:26enabler
- 00:10:27now
- 00:10:28second thing that you have to understand
- 00:10:30is like the first question why do i need
- 00:10:31to know ai i'm going to give you many
- 00:10:33examples of artificial intelligence
- 00:10:34being used in clinical impact
- 00:10:37exactly the same way that you have
- 00:10:39learned
- 00:10:40mechanism of actions of drugs all your
- 00:10:42life right like this is topo mermaid
- 00:10:45this is kapra this is a mechanism action
- 00:10:47this is the half-life this is what that
- 00:10:49is a tool that you use to help your
- 00:10:51patients exactly in the same way you're
- 00:10:54going to be using artificial
- 00:10:55intelligence in the future and exactly
- 00:10:57in the same way you need to understand
- 00:10:58some basic some mechanism of action for
- 00:11:01artificial intelligence to make sure
- 00:11:03that you are appropriately applying
- 00:11:05those tools for your patient care
- 00:11:07so do not think that artificial
- 00:11:08intelligence is something you do not
- 00:11:10need to know it is now as important as
- 00:11:12learning biochemistry in pre-med and
- 00:11:15then biochemistry in med school or
- 00:11:16anatomy or physiology there should be
- 00:11:18courses on data sciences and artificial
- 00:11:20intelligence in medicine this is not the
- 00:11:22time i can give you some more big
- 00:11:24references on where
- 00:11:25at least universities in u.s are going
- 00:11:27if you want to check out northwestern
- 00:11:28university just added a complete course
- 00:11:30on data sciences and artificial
- 00:11:32intelligence in their medical school
- 00:11:33curriculum the reason is this you are
- 00:11:36going to be taking care of these
- 00:11:37patients using these tools so you need
- 00:11:40to make sure you understand some basics
- 00:11:42at least enough that you
- 00:11:44currently know what the mechanism of
- 00:11:46action for some medicines are and choose
- 00:11:48accordingly which medication you're
- 00:11:49going to use and which you're not going
- 00:11:50to use exactly in the same way you have
- 00:11:52to start using artificial intelligence
- 00:11:54which software stack you're going to use
- 00:11:56and which you're not going to use to
- 00:11:57help this particular patient so that's
- 00:12:00why it is extremely important and this
- 00:12:01is your role as a physician to
- 00:12:03understand this in the future and the
- 00:12:05future is not that far as i told you
- 00:12:07before now when you're talking about
- 00:12:08artificial intelligence what we're
- 00:12:09talking about is machine learning and
- 00:12:11that's a lot of good term that i use the
- 00:12:13word artificial intelligence because
- 00:12:14that's a general purpose technology and
- 00:12:16there are different ways to globally
- 00:12:17tell something and the other way is not
- 00:12:19to say generally the best term to use is
- 00:12:21machine learning and the one of the key
- 00:12:23issues with the machine one of the
- 00:12:25subsets in machine learning is deep
- 00:12:26learning so let's talk about the the one
- 00:12:29two things we're going to be talking
- 00:12:30about is machine learning and deep
- 00:12:31learning machine learning is basically
- 00:12:33that when a machine basically learns
- 00:12:35from examples and deep learning is
- 00:12:37basically in which we are not giving too
- 00:12:39much labeled data and more and more
- 00:12:41excess exceptionally large amount of
- 00:12:44data is added in terms of deep learning
- 00:12:47and therefore when you are trying to
- 00:12:48explain so colloquially we use the term
- 00:12:51artificial intelligence which is to be
- 00:12:52honest with you not the right term the
- 00:12:54term we should be using is machine
- 00:12:55learning and whenever we are referring
- 00:12:57to artificial intelligence especially in
- 00:12:58healthcare we're talking about machine
- 00:13:00learning
- 00:13:00machine learning has another subset
- 00:13:02called deep learning and deep learning
- 00:13:04is basically when you have more higher
- 00:13:06forms of learning that are compute
- 00:13:08intensive and data intensive in that
- 00:13:10regard we have to see that when you are
- 00:13:13moving from machine learning to deep
- 00:13:14learning there's massively increasing
- 00:13:17amounts of requirements for data and
- 00:13:19massively increasing requirements of
- 00:13:21compute power however we lose one key
- 00:13:24issue we lose explainability because in
- 00:13:27machine learning we are giving them at
- 00:13:28least some sort of rules to go back and
- 00:13:31then we can explain that how that result
- 00:13:33was coming up to but in deep learning
- 00:13:35that is not the case let me explain
- 00:13:37further
- 00:13:38so what is the difference right i mean
- 00:13:41what's the freaking hype about in terms
- 00:13:43of artificial intelligence we have been
- 00:13:45you know have human intelligence for
- 00:13:46years and years right so we have been
- 00:13:48programming for years like it's been
- 00:13:50approximately 50 years of coding and
- 00:13:53programming that has been going on how
- 00:13:54do we do that human coders said they
- 00:13:57put in spit out a lot of instructions
- 00:13:59and rules that rules and instructions
- 00:14:01basically create a program
- 00:14:03something like this in which there's
- 00:14:04video uploaded on the youtube etc and
- 00:14:07those instructions are basically
- 00:14:08packaged and then go into it what's the
- 00:14:11difference is that then we no longer
- 00:14:13want human to code data codes we
- 00:14:17basically do not give them instructions
- 00:14:19we give them examples
- 00:14:21let me rephrase it
- 00:14:23you know there are ten thousand cat
- 00:14:25pictures and we can tell them okay do
- 00:14:27something about it then the the computer
- 00:14:29will never learn because no matter how
- 00:14:30many times you have instructions to
- 00:14:33divide that from between
- 00:14:34dog and cat it just never works this is
- 00:14:37a completely new paradigm in which you
- 00:14:39do not give instructions to the page to
- 00:14:42the computer you give okay here are a
- 00:14:44million pictures this is the dog this is
- 00:14:47the cat and then learn from it and
- 00:14:49here's another 10 000 more where you're
- 00:14:51gonna be able to distinguish between the
- 00:14:54two sets of data and test them we'll
- 00:14:56come to that in a minute so the key
- 00:14:59difference is human codes to data code
- 00:15:02instructions to examples we give tons
- 00:15:05and tons of examples to the computer and
- 00:15:08that's how it learns and that's to be
- 00:15:10honest with you is the basis of human
- 00:15:11learning as well another big difference
- 00:15:13is that that reasoning and artificial
- 00:15:15intelligence look what we have been
- 00:15:17taught about is deductive reasoning
- 00:15:19that's how we run virtually clinical
- 00:15:21trials that's how we move on in terms of
- 00:15:24scientific discovery scientific
- 00:15:26validation what do we do we have a
- 00:15:28theory that i don't know tevera made uh
- 00:15:30helps with the headache then we create
- 00:15:32that into a hypothesis then we create
- 00:15:35virtual clinical trials divide patients
- 00:15:36into two arms we do observations and
- 00:15:38then we confirm that that if our
- 00:15:41hypothesis was correct or wrong
- 00:15:44this is our current methods of thinking
- 00:15:46and this is what we call aristotle or
- 00:15:48deductive thinking
- 00:15:50sherlock or inductive thinking has been
- 00:15:52that we don't care we just say there are
- 00:15:56tons and tons of millions of you know
- 00:15:57records and and here and then just find
- 00:16:00out patterns in it and then see with the
- 00:16:02patterns if we can create some more
- 00:16:04hypothesis and then we create theory
- 00:16:07so for example there are a million
- 00:16:08epilepsy patients who are on topiramate
- 00:16:11and then we saw that they also had some
- 00:16:1210 000 of them had migraine and we saw
- 00:16:15that those patients were on top pyramid
- 00:16:16had a decreased headache frequency
- 00:16:19because they were on the
- 00:16:21that's artificial intelligence because
- 00:16:23you're putting in a lot of data which
- 00:16:25there's pattern recognition and it gives
- 00:16:27you a theory rather than the other way
- 00:16:29around so artificial intelligence is
- 00:16:31inductive reasoning artificial
- 00:16:33intelligence starts with observation
- 00:16:35examples in terms of deductive reasoning
- 00:16:38it starts with theory and confirmation
- 00:16:40so that's a completely different way of
- 00:16:41looking at things and then you will have
- 00:16:44to do a complete clinical trials as well
- 00:16:46but what ai can do is get you there
- 00:16:48faster can get you there smarter and
- 00:16:50that's where drug discoveries are being
- 00:16:52done through artificial intelligence
- 00:16:54that's exactly the pathway that they go
- 00:16:55into which was a different pathway for
- 00:16:57what we were doing before because we
- 00:16:59were now able to select compounds much
- 00:17:01faster much easier much smarter to do
- 00:17:04for clinical trials through the
- 00:17:05inductive reasoning process which uses
- 00:17:08which is based artificially intelligence
- 00:17:10is based out of
- 00:17:11and this is what i was talking about
- 00:17:12practically skipping when you have an
- 00:17:14original data format you turn it into a
- 00:17:16training data set into a testing data
- 00:17:18sometimes you do have a validation data
- 00:17:20set as well in between to hypertune your
- 00:17:23parameters but either way the logic
- 00:17:25remains the same that you take a tons
- 00:17:27and tons amount of data separate it down
- 00:17:29into training data and say okay these
- 00:17:30are label data these are cats these are
- 00:17:32dogs and then these are unlabeled data
- 00:17:34in which you know i'm going to test how
- 00:17:36do you perform in identifying those
- 00:17:39images the other thing you need to know
- 00:17:40is what's the real difference between a
- 00:17:42statistics and machine learning you
- 00:17:44understood the in reasoning behind
- 00:17:45artificial intelligences which is
- 00:17:47different than what we have been doing
- 00:17:48and that's why it's harder especially
- 00:17:50for physicians to get that because we
- 00:17:52have been ingrained into clinical
- 00:17:54evidence process in a different way
- 00:17:56now and then the tools that we have been
- 00:17:59using for years and years for clinical
- 00:18:00research has been statistics
- 00:18:03in statistics the whole goal is what
- 00:18:05relationships to understand that if this
- 00:18:08particular
- 00:18:09situation correlates with this
- 00:18:11particular disease smoking to cancer so
- 00:18:14it doesn't matter it's still not
- 00:18:16causality right we don't know if it's
- 00:18:18truly causing right it's it's at the end
- 00:18:19of the day it's a relationship that we
- 00:18:21have identifying increased risk of
- 00:18:22cancers and stroke and in smoking
- 00:18:24patients and then we infer from that
- 00:18:26particular statistics and that's why
- 00:18:28it's very explainable because we know we
- 00:18:30have run different kinds of
- 00:18:33variations of statistics and then we
- 00:18:34came to that particular conclusion
- 00:18:37and the the artificial intelligence has
- 00:18:39nothing to do with that artificial
- 00:18:41intelligence is all about prediction
- 00:18:43prediction prediction i'm sitting on a
- 00:18:45card table and i want to know what the
- 00:18:47next chord is so i can bet something
- 00:18:50different that is it
- 00:18:52the whole purpose of artificial
- 00:18:54intelligence is to predict that's where
- 00:18:56the real magic comes in if there's going
- 00:18:58to be a financial decline or if there's
- 00:19:01going to be this patient is going to
- 00:19:02develop stroke in the next 10 years this
- 00:19:05patient is going to develop heart attack
- 00:19:06in the next five years we have lots and
- 00:19:08lots of data we have millions of
- 00:19:10examples and we have seen different
- 00:19:12areas in which these patients perform
- 00:19:14differently and now we can through a
- 00:19:17significantly precise way predict
- 00:19:21where that patient is going to fall in
- 00:19:23the next five to 10 years and you can
- 00:19:25change the trajectory that's the key
- 00:19:27thing right we are in always responding
- 00:19:31quite frankly most of the time in terms
- 00:19:33of disease management and this is the
- 00:19:36paradigm shift in terms of
- 00:19:38disease management to moving from
- 00:19:40treatment to prediction and prevention
- 00:19:43so that's the key difference between
- 00:19:45statistics and machine learning because
- 00:19:47that's where we are going into in terms
- 00:19:49of artificial intelligence and it is
- 00:19:52truly based on human learning right i
- 00:19:54mean if you look at the human learning i
- 00:19:55mean if i look at one of the cat what
- 00:19:57happens i have the one neuron that goes
- 00:19:59into and then connects to different
- 00:20:00synapses to my virtual uh visual cortex
- 00:20:03and comes back and tells me okay this is
- 00:20:05a cat and exactly in the same way
- 00:20:08artificial neural networks are a design
- 00:20:11it takes one of the images divides into
- 00:20:13multiple areas and each single pixel is
- 00:20:15sometimes
- 00:20:17regulated in terms of what it is and
- 00:20:19then eventually you get a complete
- 00:20:21classification if this particular cat
- 00:20:23scan or mri has an infarction tumor or
- 00:20:26hemorrhage so what we're seeing is that
- 00:20:28that it is that's why we call it
- 00:20:30artificial intelligence because we are
- 00:20:33trying to mimic human intelligence and
- 00:20:35that's where the beauty of this whole
- 00:20:37thing comes in
- 00:20:38now
- 00:20:39another thing you need to realize as far
- 00:20:41as a difference is concerned is that
- 00:20:44what is the difference between an
- 00:20:45algorithm
- 00:20:46and artificial intelligence look we
- 00:20:49people don't understand they use the
- 00:20:50word algorithm all the time and by the
- 00:20:52way we have been using algorithms for 50
- 00:20:54years this is a basic algorithm for
- 00:20:56hyper neutrinia that we have used for
- 00:20:59many many years right i mean i'm
- 00:21:01assuming everyone has used that what's
- 00:21:03this this is basically a rule-based
- 00:21:05algorithm in which what you have done
- 00:21:07what you have done is basically you have
- 00:21:08sodium for this then you go true or
- 00:21:10pseudo and then you go to next step then
- 00:21:12you go to the next fork then you get to
- 00:21:14the next fork order some studies and
- 00:21:15then move forward this has been a
- 00:21:17rule-based algorithm and as a matter of
- 00:21:19fact to be honest with you medicine runs
- 00:21:21on this rule-based algorithms if you
- 00:21:23have a book with rule-based algorithms
- 00:21:24you can give it to a first-year
- 00:21:26medical student and he can get you
- 00:21:28somewhere in terms of moving the patient
- 00:21:30management forward
- 00:21:32what's the difference then when you have
- 00:21:34artificial intelligence
- 00:21:36you see the rules are not made there are
- 00:21:38no instructions
- 00:21:40we give a million
- 00:21:41records to the patient and tells them
- 00:21:44well this is hyponatremia what do you
- 00:21:45think it is as far as diagnosis is
- 00:21:47concerned with the million examples it
- 00:21:49finds out okay if the patient has these
- 00:21:51characteristics then it's going to fall
- 00:21:52into this bucket these characters fall
- 00:21:54into this bucket these characters will
- 00:21:56fall into this bucket creates its own
- 00:21:58database algorithm and then when you
- 00:22:00give another 10 000 new
- 00:22:02testing protocol then it can predict
- 00:22:05for you
- 00:22:07where that patient is going to be
- 00:22:08do you understand now i'm hoping that
- 00:22:10this circles in because it's hard to put
- 00:22:13these concepts into one sort of lecture
- 00:22:16so this is the whole idea behind it who
- 00:22:18will benefit from loop direct directs
- 00:22:21and you're basically going to see okay
- 00:22:22the data is going to basically tell you
- 00:22:25who is going to do that rather than you
- 00:22:27creating a rule-based system now
- 00:22:30in the beginning there will be more
- 00:22:31hybrid approaches right i mean i'm going
- 00:22:32to basically use natural language
- 00:22:34processing to
- 00:22:36figure out all the data from the emr
- 00:22:39then i'm going to have a then i'm going
- 00:22:40to have part rule-based approach and
- 00:22:42then i'm going to have something else so
- 00:22:44there are different hybrid forms of care
- 00:22:46pathways that are going on but
- 00:22:47eventually it's going to evolve into one
- 00:22:49scare pathway
- 00:22:51so in algorithm versus ai data
- 00:22:54codes
- 00:22:55not rule codes now one of the other
- 00:22:57things that are truly about artificial
- 00:22:59intelligence is that if there's a
- 00:23:01continuous stream of data those rules uh
- 00:23:04that are effect the word rule with may
- 00:23:06still be
- 00:23:07the the way the artificial intelligence
- 00:23:09predicts can change because there is a
- 00:23:11continuous stream of data and as the
- 00:23:12data changes the artificial intelligence
- 00:23:14algorithm itself can change which is
- 00:23:16very different from rule based because
- 00:23:18rule based gets stuck right this is some
- 00:23:20expert came in or whatever thousands of
- 00:23:22different uh scientific observations
- 00:23:24that created that rule-based algorithm
- 00:23:26but the benefit of artificial
- 00:23:28intelligence is that it can continuously
- 00:23:30learn and that is the key thing however
- 00:23:34that is not currently present in
- 00:23:36medicine
- 00:23:37let me give you an example
- 00:23:39this art this continuous learning is
- 00:23:41what youtube does facebook does twitter
- 00:23:44does there's a constant new trends and
- 00:23:46then they shift their algorithm models
- 00:23:48accordingly and then prevent from
- 00:23:50whatever reason and you can introduce
- 00:23:52some of different ways in which to
- 00:23:54introduce some bias and that's one of
- 00:23:56the ways that they work but what we want
- 00:23:58to do is that we should in medicine have
- 00:24:00the same opportunity but unfortunately
- 00:24:02that's not true
- 00:24:04to date i am not aware of any medical
- 00:24:07algorithm that is constantly learning
- 00:24:10they have learned from the data that
- 00:24:12algorithm has static is based on the
- 00:24:15data and is applied but it is not
- 00:24:18it is not constantly learning and the
- 00:24:20reason behind it is that there's a
- 00:24:22significant amount of clinical data
- 00:24:24shift and clinician data shift and there
- 00:24:26is their major issues um
- 00:24:29let me give you an example because that
- 00:24:31would be easier
- 00:24:32look we have a fantastic algorithm for
- 00:24:34sepsis for predicting sepsis and as a
- 00:24:36matter of fact it worked beautifully
- 00:24:38before covert but after covert the
- 00:24:40sepsis was completely different because
- 00:24:42most pre-covert sepsis was bacterially
- 00:24:44origin but post
- 00:24:46covid we had viral sepsis and those
- 00:24:50viral substances were very different for
- 00:24:52the computer to predict those viral
- 00:24:54differences it needs new forms of data
- 00:24:57so that it can predict much better we
- 00:25:00didn't do that because it's not
- 00:25:01consistently learning environment we
- 00:25:03don't have it because of multiple
- 00:25:04reasons but for now that's the biggest
- 00:25:06issue because we do not have a
- 00:25:07continuous learning environment that
- 00:25:09sepsis algorithm freaking broke as a
- 00:25:11matter of fact the company has to
- 00:25:12retract it so that's the key issue in
- 00:25:15terms of medicine and which is the the
- 00:25:17biggest issue is the data data data high
- 00:25:20quality data that you can process in
- 00:25:22real time to produce predictions in real
- 00:25:25time that could potentially be shifting
- 00:25:27because of environment country
- 00:25:29genetic background etc etc so that's the
- 00:25:32big issue why we do not have continuous
- 00:25:35learning of data engineers learning
- 00:25:38algorithm which is the true form of
- 00:25:39machine learning in medicine
- 00:25:41so that's what another vision and that's
- 00:25:43one of the key issues that another issue
- 00:25:45is i keep asking me will ai will yeah i
- 00:25:48replace physicians absolutely not
- 00:25:50now it's already the current state if
- 00:25:52you look at it it is basically combining
- 00:25:54human and ai in terms of
- 00:25:56very narrow tasks so if you have a
- 00:25:58narrow task cd brain hemorrhage or no
- 00:26:00hemorrhage yes but when i look at us cat
- 00:26:03scan i mean it's not just like if it's a
- 00:26:05bleed or not i mean it's a 70 80 year
- 00:26:07old female that has significant atrophy
- 00:26:09why the hell so i can talk about
- 00:26:11dementia possibly with the same patient
- 00:26:13while i'm talking about enzyme or
- 00:26:14talking about stroke where i see that
- 00:26:16the patient has calcification in places
- 00:26:18where there were no calcifications so in
- 00:26:20a complete narrow task artificial
- 00:26:22intelligence is right there
- 00:26:24in computer vision and i mean i'm going
- 00:26:26to talk about they're definitely places
- 00:26:28where artificial intelligence
- 00:26:30significantly lacks and there are places
- 00:26:32where artificial intelligence is better
- 00:26:33than physicians
- 00:26:35however in future we're going to see
- 00:26:37that since we're going to have more and
- 00:26:39more high quality data added we will are
- 00:26:41building data pipelines in which
- 00:26:43artificial intel data high quality data
- 00:26:45is going to be input for continuous
- 00:26:46learning we're going to see that data
- 00:26:48the the process shift in which in more
- 00:26:52and more tasks artificial intelligence
- 00:26:54is going to get better and better from
- 00:26:56humans i mean it's quite a while away
- 00:26:58about 20 to 30 years away in terms of
- 00:27:00truly seeing that massive impact in
- 00:27:03medicine there are definitely areas in
- 00:27:05which artificial intelligence is going
- 00:27:07to be the standard
- 00:27:09on which physician overlay reading will
- 00:27:11be there and this is where we come in
- 00:27:14e.i will not replace physicians however
- 00:27:16physicians that use artificial
- 00:27:18intelligence will replace a physician
- 00:27:19who do not
- 00:27:21that's something literally if this one
- 00:27:23slide that you have to take care of is
- 00:27:24this you have to learn it exactly as you
- 00:27:27have learned everything else and
- 00:27:28secondly initially at least in the
- 00:27:30majority of cases you're going to see
- 00:27:31that artificial intelligence and
- 00:27:33automation that is added is basically
- 00:27:36allowing you to have better decision
- 00:27:39support in terms of faster care no
- 00:27:41latency of care improved care outcomes
- 00:27:43etc etc but at the end of the day you
- 00:27:46have the helms of the
- 00:27:49control in terms of patient management
- 00:27:51is concerned think of it as the horse or
- 00:27:52ski lag
- 00:27:54physician
- 00:27:55but the horse is getting better the
- 00:27:56whole time ever i mean it literally it's
- 00:27:59going from a horse to our ferrari so in
- 00:28:01terms of moving in
- 00:28:03in terms of improving accuracy and
- 00:28:05improving predictions
- 00:28:07so
- 00:28:08now we come to development of artificial
- 00:28:10intelligence as i talked about data and
- 00:28:11data data look the data is is massively
- 00:28:15improving as a matter of fact there's
- 00:28:16one third of clinical data in unite in
- 00:28:19production so if there's
- 00:28:22100 data points are created about 33 of
- 00:28:25them are coming from the health care
- 00:28:26industry health care
- 00:28:28is a massive
- 00:28:30reason for expanding data in the world
- 00:28:34and we are expanding data significantly
- 00:28:36i mean youtube videos you know etc etc
- 00:28:39so we are having a lot of data that is
- 00:28:41coming out but healthcare still creates
- 00:28:43a lot of data
- 00:28:44and unfortunately that is
- 00:28:45multi-dimensional data what i mean by
- 00:28:47that is that there's disease data you
- 00:28:49know radiomics genomics biomics and then
- 00:28:52there's health data which we are you
- 00:28:54know creating with our smart watches and
- 00:28:56ecg machines voice analysis etc etc and
- 00:28:59then there's claims data you know with
- 00:29:00healthcare industries coming up with it
- 00:29:02sorry healthcare insurance is coming in
- 00:29:04and then of course we have clinical
- 00:29:05trials data
- 00:29:06bio data and clinical registries data
- 00:29:08and those can be pulled on
- 00:29:10which is important first of all there's
- 00:29:12a lot of volume but unfortunately the
- 00:29:15biggest curse in in
- 00:29:17medicine is that it deman it's
- 00:29:19dimensional over time as well so my body
- 00:29:21metabolics is very different when i was
- 00:29:2320 years old i mean i'm becoming an old
- 00:29:25man now so clearly the metabolics have
- 00:29:27changed so over time the data
- 00:29:29characteristics change so that's where
- 00:29:31the curse of dimensionality in
- 00:29:32healthcare comes in
- 00:29:34and then more importantly more and more
- 00:29:36convergence is happening right i mean as
- 00:29:37i said we have more digital therapeutics
- 00:29:40are coming up which is going to create
- 00:29:41new forms of data we're going to have
- 00:29:43new forms of genetic analysis which
- 00:29:45creates more data then we have new
- 00:29:47manufacturing done so there was more
- 00:29:48data so we're going to have more and
- 00:29:50more data coming in into the pipeline
- 00:29:52that no matter what you do you're going
- 00:29:54to need artificial intelligence to churn
- 00:29:56it period there's no other way around it
- 00:29:58because it's just impossible for anyone
- 00:30:00to take that into a data science and
- 00:30:02then make sense of it because you have
- 00:30:04to have that that data to be done and
- 00:30:07that's where another thing comes in you
- 00:30:09do have to have a purpose right you just
- 00:30:11don't collect data for no reason you
- 00:30:13collect data to process it that's key
- 00:30:16thing that is why the development of
- 00:30:18artificial intelligence is going to
- 00:30:19happen in stacks so i don't know if you
- 00:30:22have any brother or sister in in
- 00:30:24software services but you should talk to
- 00:30:26them they talk about software as a
- 00:30:28service sas that's the key term software
- 00:30:30as a services basically you find a small
- 00:30:32problem and you develop an automation
- 00:30:34solution on it and then you apply it to
- 00:30:36the big stack and then you another
- 00:30:37problem big stack another problem is
- 00:30:39stack it's exactly the same artificial
- 00:30:41intelligence is developing medicine i
- 00:30:43have a problem in terms of artificial in
- 00:30:45stroke i have medical imaging analysis
- 00:30:48through computer vision one stack i need
- 00:30:50natural language processing to process
- 00:30:52patient reported data or also clinical
- 00:30:55reports i have another uh
- 00:30:58transfer and management issue that do
- 00:30:59that i have another stack of genomics
- 00:31:02all these stacks are currently going to
- 00:31:03be in development on different stacks
- 00:31:06and these are software services
- 00:31:08eventually these software and services
- 00:31:09is going to become immature and then
- 00:31:11when they're going to become mature
- 00:31:12they're going to combine and when
- 00:31:14they're going to converge that's going
- 00:31:15to turn into a full artificial
- 00:31:17intelligence that is going to be more
- 00:31:19more usable and believe me uh this is
- 00:31:21disruptive and can happen suddenly like
- 00:31:23the kodak moment right i mean nobody's
- 00:31:25using plain films anymore everyone's
- 00:31:27doing digital photography and i have
- 00:31:29another lecture on the convergence of
- 00:31:30virtual care and artificial intelligence
- 00:31:32because the virtual care is now becoming
- 00:31:34a very important part of producing
- 00:31:36ground truth valuable confirmed
- 00:31:39validated data in clinical so therefore
- 00:31:42we're you know if you're interested in
- 00:31:43looking at convergence more you can look
- 00:31:45at that lecture
- 00:31:46now
- 00:31:48there are three different pillars of
- 00:31:49artificial intelligence one of them is
- 00:31:51computer vision which goes about digital
- 00:31:53pathology etc then predictive analytics
- 00:31:56and natural language processing
- 00:31:58so let's go into that so computer vision
- 00:32:00is all about neuroideology in your terms
- 00:32:02and neuropathology and then in terms of
- 00:32:04video analysis if the patient is walking
- 00:32:05you can see if the patient has stranded
- 00:32:08walk is it the spine issue is it the
- 00:32:10multiple sclerosis patient in which we
- 00:32:12are using image and video analysis to
- 00:32:15quantify that walk and how the other
- 00:32:17medic the new medication you're going to
- 00:32:19develop is going to improve so we're not
- 00:32:21going to talk about virtual clinical
- 00:32:22trials right now but the idea is that
- 00:32:24image and video analysis computer vision
- 00:32:26then we have predictive analytics and
- 00:32:28this is where the decision support and
- 00:32:30trend analysis comes in simple pulse
- 00:32:32oximetry is coming through the icu you
- 00:32:33can say that if the pulse ox is changing
- 00:32:35is the patient developing high increase
- 00:32:37intracranial pressure or as the patient
- 00:32:39has different heart rates and
- 00:32:41blood pressure monitoring are changing
- 00:32:43can you predict at least sometimes it as
- 00:32:44a matter of fact their studies have
- 00:32:46predicted a sudden uh development of
- 00:32:48cardiac arrest in eyes sick sepsis
- 00:32:51patients up to 15 minutes earlier so
- 00:32:54that's where the prediction trend
- 00:32:55analysis come in in the predictive
- 00:32:56analytics analytics portion and then
- 00:32:59finally natural language processing
- 00:33:01natural language processing is the most
- 00:33:02exciting and the most important feature
- 00:33:05as a matter of fact um
- 00:33:07that's why google shines a lot in terms
- 00:33:10of you know its prowess in artificial
- 00:33:12intelligence because that their whole
- 00:33:14thing was behind search is natural
- 00:33:17language processing all that word data
- 00:33:19on the internet and how to collect
- 00:33:21accumulate and create wisdom from it
- 00:33:24there are two areas in it one is speech
- 00:33:25and the other one is text speeches text
- 00:33:27to speech speech to text all of them use
- 00:33:29artificial intelligence and as far as
- 00:33:31text is concerned classification of that
- 00:33:34extraction of that summarization of that
- 00:33:35translation of that as a matter of fact
- 00:33:37ibm watson was
- 00:33:39summarizing automatically
- 00:33:41some of the cancer trials and while the
- 00:33:43patient is being seen and when you
- 00:33:45search on that they would recommend uh
- 00:33:47which clinical trial is applicable to
- 00:33:49that particular patient and pull up a
- 00:33:51summary of that as well so clearly there
- 00:33:53are different areas where there are
- 00:33:55applications but this is a sort of a
- 00:33:57chart for you to understand
- 00:33:58what different areas of artificial
- 00:34:00intelligence are and what they are
- 00:34:01concentrating on
- 00:34:03and we talked about data and convergence
- 00:34:06data data data it is all about data
- 00:34:08and uh data is literally the new oil
- 00:34:11nobody talks about enron as the most
- 00:34:13valuable company we talk about google
- 00:34:14facebook tesla amazon and the reason
- 00:34:17that tesla is the most valuable company
- 00:34:18is because it doesn't have a freaking
- 00:34:20four wheels that is better than any
- 00:34:21other car because it is not a car
- 00:34:23company it is a data company
- 00:34:25and
- 00:34:26one of the key things that you need to
- 00:34:28keep working on and this is one of the
- 00:34:30most important papers from last year is
- 00:34:32that everyone wants to do the sexy model
- 00:34:34work in artificial intelligence and i
- 00:34:35want to create models and then turn
- 00:34:37algorithms and everything
- 00:34:39data work is the most important work if
- 00:34:41you have a beautiful data like data
- 00:34:43pipeline you will have
- 00:34:46golden area to develop artificial
- 00:34:48intelligence to develop ground truth and
- 00:34:50once you have that you can be amazing in
- 00:34:52terms of artificial so data work data
- 00:34:54work data work it is not just modeling
- 00:34:57and all that to be honest it's getting
- 00:34:59very easy one of the other things you
- 00:35:01have to remember whenever you provide
- 00:35:03automation to anything automation is
- 00:35:05like a catalyst if you have a process
- 00:35:08that is garbage it's gonna catalyze
- 00:35:10garbage into more garbage and if you
- 00:35:12have an area in which you are efficient
- 00:35:15and you put in a catalyst then that
- 00:35:17efficiency is going to be expanded as
- 00:35:18well so it's very important that
- 00:35:21wherever artificial intelligence is
- 00:35:22applied it is applied in a process that
- 00:35:26has been optimized and efficient before
- 00:35:28you apply artificial intelligence
- 00:35:30because if you don't then that ai is
- 00:35:32going to be a bigger problem in terms of
- 00:35:35where it is because it basically is a
- 00:35:37tool it is a catalyst anytime you have
- 00:35:39that sort of automation make sure that
- 00:35:41you have that
- 00:35:42silk smooth out before you make
- 00:35:44applications
- 00:35:47now let's get to artificial intelligence
- 00:35:49and neurology we're going to talk
- 00:35:50quickly about two major things one is
- 00:35:53stroke you see stroke is 861 billion
- 00:35:56problem huge issue there's increasing
- 00:35:58incidence increasing debts people are
- 00:36:00living with it more more and more as a
- 00:36:02matter of fact if you literally do one
- 00:36:03minute delay you are basically cleaning
- 00:36:061.9 million neurons and 14 billion
- 00:36:08synapses and if there's a fast
- 00:36:10progressive stroke you can use a limb
- 00:36:13lose a limb completely in five minutes
- 00:36:16we definitely need to reduce time right
- 00:36:18if you're not going to reduce time
- 00:36:20we're going to have a big issue and
- 00:36:22that's where artificial intelligence
- 00:36:23comes in and this is one of the earliest
- 00:36:26application of artificial intelligence
- 00:36:27that is commercially available
- 00:36:30and
- 00:36:30viable
- 00:36:31there's a difference commercially
- 00:36:33available clearly this is fda approved
- 00:36:34people have seen it people have applied
- 00:36:36it i use this software every day in my
- 00:36:38life and i'm providing stroke care and
- 00:36:41it is getting reimbursed so people are
- 00:36:43getting paid for the hard work and
- 00:36:45artificial intelligence they have done
- 00:36:46because it's just not about academics
- 00:36:48it's about producing
- 00:36:50a product that is commercially viable
- 00:36:52and reimbursable
- 00:36:54so
- 00:36:54there are multiple software packages
- 00:36:57this is one visa i don't know if you're
- 00:36:58aware of dr adnan siddiqui and amir
- 00:37:00hussain they are fantastic people here
- 00:37:02in us amir is from egypt and atlanta
- 00:37:04she's from pakistan who has done this
- 00:37:06study and showed that artificial in
- 00:37:08intelligence decreases latency to care
- 00:37:10by 66 minutes think about the number of
- 00:37:13limbs
- 00:37:14you can save in lives you can save with
- 00:37:16that because you can get to the patient
- 00:37:18faster and earlier if you don't have a
- 00:37:20thermectomy center it's to
- 00:37:22apply it right you have an efficient
- 00:37:24system
- 00:37:25to get efficient results you just don't
- 00:37:27put artificial intelligence where you
- 00:37:29can't create a difference so remember
- 00:37:31that but at the end of the day that
- 00:37:33these are the value that artificial
- 00:37:34intelligence is bringing we can see it
- 00:37:36in interstable hemorrhage dissection we
- 00:37:38can automate it into stable hemorrhagic
- 00:37:40detection as we want we can have
- 00:37:42significant amount of commercial
- 00:37:43software that are available this is the
- 00:37:45list
- 00:37:46that is there and you have to find the
- 00:37:48right problem to find the right solution
- 00:37:51this is a
- 00:37:53complete video that i did
- 00:37:54make sure you look at it in terms of
- 00:37:56role of artificial intelligence and
- 00:37:57telestroke and how it
- 00:38:00becomes more than life in terms of
- 00:38:02decreasing the latency of care itself
- 00:38:06and this is the paper that got published
- 00:38:08about the same thing
- 00:38:09in terms of role of artificial
- 00:38:11intelligence and stroke and telestroke
- 00:38:14the second big reason is biomarkers i
- 00:38:16told you about it because one of the key
- 00:38:18issues in
- 00:38:19prediction of neurological disorders is
- 00:38:22to have something that i can have to to
- 00:38:25diagnose the patient and more
- 00:38:27importantly not just the diagnosis early
- 00:38:29diagnosis so i can make a change to
- 00:38:31predict how the patient is going to move
- 00:38:33and then any intervention early
- 00:38:35intervention that can be done to correct
- 00:38:38that bad pathological pathway that is
- 00:38:40moving forward it is most important in
- 00:38:43terms of stroke and in terms of
- 00:38:47alzheimer's and everything and we're
- 00:38:48working on it right it's not like we're
- 00:38:50not stopped working on blood
- 00:38:53based biomarkers we're looking at
- 00:38:54hemorrhaging we're looking at
- 00:38:56subarachnoid hemorrhage we're looking at
- 00:38:57csf analysis in some of these patients
- 00:38:59to find
- 00:39:01lab-based biomarkers blood-based
- 00:39:03serum-based biomarkers for these
- 00:39:05patients however it is becoming harder
- 00:39:07and harder and we have to produce
- 00:39:09different methods of doing it and one of
- 00:39:11the method is
- 00:39:13using deep learning artificial
- 00:39:15interlearning in a multimodal way to
- 00:39:18predict
- 00:39:19early if there is anything going on and
- 00:39:21one of the best applications this has
- 00:39:23been in alzheimer's in which what we're
- 00:39:25seeing is that we can combine imaging
- 00:39:27genetics and clinical test data this is
- 00:39:30not available commercially this is
- 00:39:32currently in research only however what
- 00:39:36we are seeing the trend going forward is
- 00:39:38that when we have combination of these
- 00:39:41different data sources i can predict
- 00:39:44alzheimer's at the age of 55 what am i
- 00:39:46going to do with it well currently
- 00:39:47nothing i mean there's only one drug
- 00:39:49that is available which is highly
- 00:39:50controversial but at the end of the day
- 00:39:52if i have to develop a drug i cannot
- 00:39:54give it to a person who already has
- 00:39:56advanced dementia what am i going to do
- 00:39:57the brain is already
- 00:39:59problematic we need to early intervene
- 00:40:01so the minute i'm able to have
- 00:40:03authenticated clinically validated
- 00:40:06digital or multi-modal biomarker i can
- 00:40:09intervene with a new medication study
- 00:40:11that medication and see how it goes so
- 00:40:14we're going to see that more and more as
- 00:40:16far as biomarkers are concerned
- 00:40:18now i have all of this and more in terms
- 00:40:21of my courses that are coming
- 00:40:23as far as how to choose a medical
- 00:40:25specialty in this new post
- 00:40:27pandemic digital healthcare era in which
- 00:40:29i'm going to talk about artificial
- 00:40:30intelligence virtual care and advanced
- 00:40:32practice providers and i'm going to be
- 00:40:35giving out a total of 100 participants
- 00:40:37significant discount in honor of dr
- 00:40:40wasse so i'm going to send it because he
- 00:40:42is a beacon of neurology in pakistan and
- 00:40:45i have been impressed that how he has
- 00:40:48managed to do all this all the time so
- 00:40:50i'm going to send it to him and he can
- 00:40:52distribute the codes to anyone and
- 00:40:54people can take this other course in
- 00:40:57much more detail as far as artificial
- 00:40:59intelligence virtual care and other
- 00:41:01things like lifestyle considerations
- 00:41:02financial considerations etc so it's
- 00:41:05being built it's going to be available
- 00:41:06next month and i hope to see you there
- 00:41:08as well
- 00:41:09another thing that you might want to
- 00:41:10help me with is about
- 00:41:12neurologypocketbook.com
- 00:41:14you can go there multiple chapters that
- 00:41:15i'm adding about digital neurology in
- 00:41:17terms of what is digital health what is
- 00:41:19m health
- 00:41:21mobile health in neurology and then
- 00:41:23there are chapters on digital education
- 00:41:25in neurology artificial intelligence
- 00:41:27neurology like staple ischemia and this
- 00:41:28is all open access so you can copy paste
- 00:41:31it put it in your presentations etc and
- 00:41:33maybe contribute if you want to
- 00:41:35this is the website and then of course
- 00:41:37everything that i do is on one link tree
- 00:41:39including twitter etc all that thank you
- 00:41:43so much for your help and i'm very very
- 00:41:45grateful for your time if you save a
- 00:41:46life it is as if you saved the life of
- 00:41:48mankind please make sure you like
- 00:41:50comment share and subscribe to my
- 00:41:52youtube channel and my newsletter if you
- 00:41:55want to get in touch with me the best
- 00:41:56way is to go through twitter or while
- 00:41:58linkedin also make sure you follow the
- 00:42:00academy website for regular updates
- 00:42:02thank you so much
- Artificial Intelligence
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