CNS 2025: Keynote Address by Adriana Galván, "Adolescent Brain Development"
Resumen
TLDRThe 32nd annual meeting of the Cognitive Neuroscience Society, co-chaired by Michael Anderson and Sabina Castner, features a diverse program with contributions from various committees. The keynote address by Adriana Galvan focuses on adolescent brain development, emphasizing the significance of social connections, joy, and strategic risk-taking. Galvan advocates for translating neuroscience research into policies that support adolescents, highlighting their unique developmental needs and the impact of the environment on brain growth. The conference also honors distinguished scientists and encourages engagement with emerging research in cognitive neuroscience.
Para llevar
- 🎉 Welcome to the 32nd annual meeting of the Cognitive Neuroscience Society!
- 👩🔬 Keynote speaker Adriana Galvan focuses on adolescent brain development.
- 🧠 Adolescence is a critical period for forming new neural pathways.
- 🤝 Social connections are vital for adolescent development.
- 🎓 The conference features awards for distinguished scientists.
- 📚 Research can inform policies that support adolescents.
- 🌍 The environment significantly impacts brain development.
- 💡 Adolescents are strategic risk-takers, learning through experiences.
- ❤️ Embracing joy is important during adolescence.
- 📈 The Center for the Developing Adolescent aims to translate research into practice.
Cronología
- 00:00:00 - 00:05:00
Michael Anderson welcomes attendees to the 32nd annual Cognitive Neuroscience Society meeting, acknowledging the efforts of various committees and individuals who contributed to organizing the event. He highlights the exciting program, including invited sessions on cognitive functions, lesion methods, EEG insights, and the cognitive thalamus, as well as a record number of poster submissions. Anderson encourages attendees to engage with scientists and participate in workshops and social events throughout the conference.
- 00:05:00 - 00:10:00
Sabina Castner expresses her happiness to be part of the scientific community and introduces keynote speaker Adriana Galvan, who specializes in adolescent brain development. Galvan's research focuses on the neural mechanisms underlying adolescent behavior and the importance of this developmental stage. She has published extensively and received numerous accolades for her work, including a Fulbright scholarship and a Presidential Early Career Award.
- 00:10:00 - 00:15:00
Adriana Galvan begins her keynote address by discussing the unique qualities of adolescents, portraying them as 'superhumans' who excel in learning and social bonding. She aims to shift the negative narrative surrounding adolescence and emphasizes the need for policies that support their development. Galvan shares her personal connection to the topic as both a researcher and a parent of a teenager, highlighting the importance of understanding adolescent brain development.
- 00:15:00 - 00:20:00
Galvan explains that adolescence spans from around 10-12 years old to the early 20s, a period often overlooked in terms of funding and research focus. She references a 2018 Nature editorial that calls for more attention to adolescent health, paralleling the focus given to pediatrics and geriatrics. Galvan emphasizes the need for a supportive environment to foster healthy brain development during this critical time.
- 00:20:00 - 00:25:00
The National Academy of Sciences report on adolescence highlights the creation of new neural pathways during this developmental stage, influenced by environmental factors. Galvan stresses the importance of celebrating adolescence and recognizing their unique developmental needs, which include exploring the world, building decision-making skills, forming values and identity, and seeking social connections.
- 00:25:00 - 00:30:00
Galvan outlines seven developmental needs of adolescents, including the importance of support from caregivers and the need for a nurturing environment to achieve developmental milestones. She emphasizes that adolescents continue to require guidance and support from adults, despite the common perception that they are solely focused on their peers.
- 00:30:00 - 00:35:00
Galvan discusses the ongoing brain development during adolescence, characterized by organized and sequential growth, refinement of brain connectivity, and significant plasticity. She explains that the brain's ability to adapt and respond to the environment is crucial for developing cognitive skills and social connections during this period.
- 00:35:00 - 00:40:00
The keynote address highlights the importance of joy in adolescence, as their reward systems are highly sensitive, allowing them to learn and adapt quickly. Galvan shares research findings that demonstrate adolescents' heightened sensitivity to rewards and their ability to learn from new experiences, which is essential for navigating the complexities of social interactions and decision-making.
- 00:40:00 - 00:47:29
Galvan concludes by discussing the need for scientists to communicate their findings to policymakers and the public, emphasizing the impact of research on adolescent development in various sectors, including education and the justice system. She encourages a collaborative approach to support adolescents and promote their well-being, advocating for policies that recognize their unique developmental needs.
Mapa mental
Vídeo de preguntas y respuestas
Who is the keynote speaker at the conference?
The keynote speaker is Adriana Galvan, a professor of psychology at UCLA.
What is the focus of Adriana Galvan's research?
Her research focuses on adolescent brain development and its implications for behavior and policy.
What awards are being presented at the conference?
Awards include the George Miller award, Distinguished Career Contributions award, and Young Investigator awards.
What is the significance of the adolescent brain development period?
This period is crucial for forming new neural pathways and developing social and cognitive skills.
What are some key themes discussed in the keynote address?
Key themes include the importance of social connections, joy, and strategic risk-taking in adolescence.
How can neuroscience research impact policies for adolescents?
Research can inform policies that better support the developmental needs of adolescents.
What is the role of the Cognitive Neuroscience Society?
The society organizes conferences and promotes research in cognitive neuroscience.
What is the importance of the environment in adolescent brain development?
The environment plays a critical role in shaping brain development and the formation of neural connections.
What are some developmental needs of adolescents?
Developmental needs include exploring the world, building decision-making skills, and forming identity.
What is the goal of the Center for the Developing Adolescent?
The center aims to translate adolescent neuroscience research into practical applications and policies.
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- 00:00:05Good evening. I'd like to welcome you
- 00:00:06all to the 32nd annual uh meeting of the
- 00:00:09Cognitive Neuroscience Society. Uh I'm
- 00:00:12Michael Anderson from the University of
- 00:00:14Cambridge and I am co-program chair this
- 00:00:16year together with Sabina Castner from
- 00:00:18Princeton University. I'm the outgoing
- 00:00:20chair and she is the incoming chair. Um
- 00:00:24I I'd like to say a few words before we
- 00:00:26get started, words of thanks. uh because
- 00:00:30a conference of this magnitude, of this
- 00:00:32size, is no easy feat to put together.
- 00:00:35It's a very complex affair indeed. It
- 00:00:37involves no less than six different
- 00:00:39committees. For for example, can't use
- 00:00:43my classes. uh the the program
- 00:00:44committee, the symposium committee, the
- 00:00:46poster committee, the young investigator
- 00:00:48awards committee, the rising star
- 00:00:50committee, the CNS training trainee
- 00:00:52association, not to mention the members
- 00:00:55of the cognitive neuroscience society
- 00:00:56organization itself like Kate Treway,
- 00:00:59Carrie Miller, and Lisa Munos for
- 00:01:01example. Uh so all of these people have
- 00:01:04invested a significant amount of time in
- 00:01:07evaluating the content that's been
- 00:01:08submitted to our society to ensure that
- 00:01:11you have a high quality cutting edge
- 00:01:14exciting program uh to attend to attend.
- 00:01:18Um just to give you a little bit of a
- 00:01:21flavor I got two microphones here. You
- 00:01:23get a little bit of a flavor of some of
- 00:01:24the content that you're going to be
- 00:01:25hearing about this year. Just in the
- 00:01:28invited sessions, we have a session
- 00:01:29organized by Anna Shapiro on the
- 00:01:32cognitive functions of replay. Uh a
- 00:01:35session organized by Lesie Fellows on
- 00:01:38advances in lesion methods in cognitive
- 00:01:40neuroscience. A session organized by Ben
- 00:01:43Heath uh which is kind of a deep dive
- 00:01:45into what EEG uh has taught us in
- 00:01:48cognitive neuroscience. and a session
- 00:01:50organized by Kai Hang of the University
- 00:01:52of Iowa on uh the the cognitive phalamus
- 00:01:56the the attentional functions of of the
- 00:01:58phalamus and the cognitive functions
- 00:01:59more broadly and that's just the invited
- 00:02:02sessions the membered submitted sessions
- 00:02:05are more numerous and diverse and
- 00:02:08exciting than than even that I think
- 00:02:11you're going to have a hard time
- 00:02:12choosing which things to go to. I I
- 00:02:14certainly you're not going to be able to
- 00:02:15go to everything that you want to go to.
- 00:02:17I certainly won't be able to uh th this
- 00:02:20is not even mentioning the the numerous
- 00:02:22and I think record number of posters
- 00:02:24submitted to our society this year. Uh
- 00:02:26the multiple sessions I I really
- 00:02:28encourage you to try to attend as many
- 00:02:30of these as you can because it gives you
- 00:02:32a chance to talk directly face-toface
- 00:02:35with the scientists producing some of
- 00:02:37the most exciting scientists on the
- 00:02:39horizon of our field. Uh and I think
- 00:02:41they really appreciate it and I think
- 00:02:43you'll really appreciate it as well. We
- 00:02:45have an array of uh lunchtime workshops
- 00:02:48which are easy to miss as you're running
- 00:02:50for your sandwich outside because you're
- 00:02:53so hungry. You may overlook that there's
- 00:02:55a really cool workshop that you could be
- 00:02:57participating in that's directly
- 00:02:58relevant to you. So be sure to to take a
- 00:03:00peek at that in the symposium or in the
- 00:03:03in the in the program. Um we have uh the
- 00:03:07society has chosen to honor a number of
- 00:03:10distinguished scientists this year both
- 00:03:12at the senior level and at the junior
- 00:03:14level. Uh the this year's George Miller
- 00:03:17award recipient is professor Ken Per. Uh
- 00:03:21the distinguished career contributions
- 00:03:23award is uh professor Marie Banich. And
- 00:03:26then we have two young investigators
- 00:03:28early career scientists Emily Finn and
- 00:03:31Andre Bastos. uh each of them will be
- 00:03:34giving uh an award address and I think
- 00:03:37this is going to be really really
- 00:03:38exciting to attend you should check it
- 00:03:40out and see see what all the excitement
- 00:03:42is about and why why they were given the
- 00:03:44their awards.
- 00:03:47Um they on Sunday when you're done
- 00:03:50checking out all the science you can
- 00:03:51handle on Sunday on Sunday night there's
- 00:03:54a performance by Pavlov's dogs at the
- 00:03:57Canab lounge. Uh you should you should
- 00:03:59definitely definitely see they're always
- 00:04:01a good time. uh the CNS traininee uh uh
- 00:04:07committee has organized a panel
- 00:04:09discussion on late Monday night or not
- 00:04:12late Monday night late Monday afternoon
- 00:04:14early evening and it's followed by a CNS
- 00:04:16trainee social immediately after that
- 00:04:19and I think that that this is talking
- 00:04:20about career possibilities uh for for
- 00:04:23young for for early career scientists uh
- 00:04:27immediately after tonight's uh uh
- 00:04:29keynote address uh which Sabina will be
- 00:04:32introducing
- 00:04:33Uh there will be a reception in the
- 00:04:35lobby and I look forward to seeing many
- 00:04:38of you there. Thank you very much.
- 00:04:42[Applause]
- 00:04:52Yeah, good afternoon. These are bright
- 00:04:54lights. Um well, I'm Sabina Castnim. I
- 00:04:58serve together with Mike as a chair of
- 00:05:00the program committee.
- 00:05:02And I just want to say how incredibly
- 00:05:05happy I am to be in this community of
- 00:05:09strong scientists at this point in
- 00:05:12time. Now it is my pleasure and a
- 00:05:15privilege to introduce our keynote
- 00:05:18keynote speaker Adriana
- 00:05:20Galvan. Adriana is a professor of
- 00:05:23psychology and the dean and vice provost
- 00:05:25of undergraduate education at the
- 00:05:28University of California at Los Angeles.
- 00:05:32She's also the co-executive director of
- 00:05:34the UCLA Center for the Developing
- 00:05:37Adolescent. In her science career,
- 00:05:40Eduana has been focused on the
- 00:05:41adolescent brain development and how it
- 00:05:44supports developmental
- 00:05:46milestones during this important period
- 00:05:49of life. Her research expertise focuses
- 00:05:52on characterizing the neurom mechanisms
- 00:05:55underlying under adolescent behavior to
- 00:05:58inform policies that impact young
- 00:06:03people. Adriana has published over 130
- 00:06:07scientific articles on the topic and she
- 00:06:10is the author of a book the neuroscience
- 00:06:13of adolescence.
- 00:06:16She received her BA in neuroscience and
- 00:06:18behavior from Barnard College at
- 00:06:21Columbia
- 00:06:22University and her PhD in neuroscience
- 00:06:25from
- 00:06:26Cornell. She has received multiple
- 00:06:28recognitions for her work including from
- 00:06:31the National Academy of Sciences, the
- 00:06:33American Psychological Association, the
- 00:06:36Cognitive Neuroscience Society, and the
- 00:06:39William T. Grant Foundation. She is also
- 00:06:42the recipient of the UCLA Gold Shield
- 00:06:46Faculty
- 00:06:47Prize. In 2018, Adriana was a Fulbright
- 00:06:51scholar in Barcelona. And in 2019, she
- 00:06:55received the White House Presidential
- 00:06:58Early Career Award for Science and
- 00:07:00Engineers, which is, I think, the
- 00:07:02highest honor for an early career
- 00:07:06researcher. So, we are now looking
- 00:07:08forward to Dr. Gavan's keynote address
- 00:07:11and it's entitled adolescent brain
- 00:07:14development the importance of
- 00:07:16connections. Please help me welcome
- 00:07:19[Applause]
- 00:07:26Juliana. Um so nice to be here. I really
- 00:07:30enjoy this community and it's wonderful
- 00:07:32to see friends and family. you feel like
- 00:07:34family um from present time and then
- 00:07:37also from all the years I spent training
- 00:07:40in various spaces. As Sabina mentioned,
- 00:07:42I'll be talking about some research
- 00:07:44we've been doing in our lab and labs
- 00:07:45across the world about how adolescence
- 00:07:48develops and how brain development
- 00:07:50during this time is essential for them
- 00:07:52to um develop into
- 00:07:54adults. I really appreciate the the
- 00:07:58opportunity to deliver this keynote
- 00:08:00speech and um and hope you will find it
- 00:08:02informative.
- 00:08:04Imagine if there existed a group of
- 00:08:06people who laugh easily, prioritize
- 00:08:09bonding with others, could learn faster
- 00:08:11than anyone in this room, and embrace
- 00:08:13the uncertainty of life. We might call
- 00:08:16them superhumans. We'd certainly study
- 00:08:18them and love them and want to be them.
- 00:08:21Well, it turns out that this magical
- 00:08:23group of people live among us, and
- 00:08:25they're called teenagers. And that's
- 00:08:27what I'll be talking about today.
- 00:08:30Despite the bad rap that adolescence get
- 00:08:33in the very spaces that can help them
- 00:08:34the most, sometimes in in school
- 00:08:36settings or in legal spaces, um this
- 00:08:40this talk I'm going to give is a
- 00:08:41feel-good story of adolescence and this
- 00:08:43wondrous time of life and what we can
- 00:08:45learn from them and how we as scientists
- 00:08:47can further advance their development by
- 00:08:50translating the science into spaces that
- 00:08:53need adolescence policy and legal
- 00:08:56spaces. How do I know this? Well,
- 00:08:59besides the fact that I um myself was a
- 00:09:02teenager at one point, I'm the second
- 00:09:03from the left there in high school. I am
- 00:09:06now the parent of an adolescent. That's
- 00:09:08my son Gustavo who's 14. Um I've spent
- 00:09:11over 20 years studying the adolescent
- 00:09:13brain. And this is a picture from the
- 00:09:152003 John Merks Fund summer institute at
- 00:09:18Princeton run by BJ Casey. And some of
- 00:09:21the people you can see here have gone on
- 00:09:23to be some of the most renowned
- 00:09:24developmental scientists in the world.
- 00:09:26And at this time upon reflection we were
- 00:09:29just learning how to use cognitive
- 00:09:31neuroscience skills to inform the
- 00:09:33developing brain or understanding of the
- 00:09:34developing brain. And since then we've
- 00:09:37learned a lot about it. In those early
- 00:09:39years there was a lot of misconceptions
- 00:09:41about adolescence and often framed in
- 00:09:43negative light.
- 00:09:46When I refer to adolescence, I'm talking
- 00:09:48roughly the period of 10 or 11 or 12
- 00:09:51when puberty strikes into the early 20s
- 00:09:54when we adopt social roles that may be
- 00:09:56defined as as adolescent like or
- 00:09:58adult-like or more
- 00:10:00mature. There's vast variation during
- 00:10:03this time in life, but it does span a
- 00:10:05long time. And what's surprising is that
- 00:10:08despite the many years that we spend
- 00:10:10being adolescence, there's much less
- 00:10:12attention paid to it in terms of how
- 00:10:14many dollars we expend, federal dollars
- 00:10:16we expend or how much attention is given
- 00:10:17to adolescence.
- 00:10:19This editorial in the journal Nature in
- 00:10:222018 characterized it as really nicely
- 00:10:26and they said a modern health care
- 00:10:27system without a focus on the unique
- 00:10:29challenges of pediatrics or geriatrics
- 00:10:32would be unthinkable and yet there's no
- 00:10:34similar effort on behalf of adolescence.
- 00:10:36Luckily that's changing because
- 00:10:38adolescence need us and as I hope I will
- 00:10:40convey in this talk we need adolescence.
- 00:10:46One testament to that is a now
- 00:10:48relatively recent um report consensus
- 00:10:52report by the national academy of
- 00:10:53science of uh and engineering the
- 00:10:55promise of adolescence. And throughout
- 00:10:57this report I highly encourage you to
- 00:10:59read it. They note that the latest brain
- 00:11:01development research shows that the
- 00:11:03developmental period from adolescence
- 00:11:05through emerging adulthood features the
- 00:11:07creation of new neural pathways. And of
- 00:11:10course that doesn't just happen onto
- 00:11:11genetically but it's in response to the
- 00:11:13environment. And so the environment that
- 00:11:14we create for young people is really
- 00:11:16important for how their brains will
- 00:11:19develop. And this has helped this this
- 00:11:21narrative has helped shift how we talk
- 00:11:23about
- 00:11:24adolescence. In that same editorial from
- 00:11:272018, there was an a note about how
- 00:11:30adolescence research must grow up. We
- 00:11:32need to stop giving adolescence a raw
- 00:11:34deal and start celebrating who they are.
- 00:11:38In part, I think that this this shift
- 00:11:40has um has happened because we've
- 00:11:42learned that our work can have an impact
- 00:11:44on the policies that impact young
- 00:11:46people. Policy makers and legal scholars
- 00:11:49turn to those who study adolescence to
- 00:11:51gain insights into how best to support
- 00:11:53young people. And I'll talk about that a
- 00:11:55little bit in the second part of the
- 00:11:58talk. What can we learn from
- 00:12:00adolescence? We can learn a lot. we can
- 00:12:02help them. But there's a lot that that
- 00:12:04inherently happens during this
- 00:12:06transitional period of life that we as
- 00:12:08adults can learn from them. And I'll
- 00:12:09give a little uh syn synthesis of each
- 00:12:12of these areas of research that support
- 00:12:14these claims. The first is that we can
- 00:12:17embrace joy. Adolescence are really good
- 00:12:19at that and sometimes we don't
- 00:12:20acknowledge it. The second is that
- 00:12:22adolescence are strategic risktakers
- 00:12:25that all the risks that they take are
- 00:12:27are important. um they offered learning
- 00:12:30opportunities that the brain is primed
- 00:12:32to receive during this period of
- 00:12:34life. And finally, adolescence
- 00:12:37prioritize social connections. Perhaps
- 00:12:39now more than ever, social connections
- 00:12:41are paramount to who we are as a
- 00:12:42species. And we are inherently driven to
- 00:12:45connect with other people. And
- 00:12:46adolescence are really good at doing
- 00:12:48this. Whether it's through uh online or
- 00:12:51offline, they they embrace this
- 00:12:53opportunity to meet new people.
- 00:12:58When we are babies, we achieve
- 00:13:01developmental milestones during infancy.
- 00:13:03We learn how to walk and how to talk and
- 00:13:06how to bond with caregivers. And these
- 00:13:08milestones are best achieved when key
- 00:13:11developmental needs are met. Primarily
- 00:13:13when we have support and love and
- 00:13:15attention that we need and deserve. And
- 00:13:18no, no one argues this point that during
- 00:13:21during this time in life, there's an
- 00:13:23optimal rearing environment that
- 00:13:25optimizes achieving these developmental
- 00:13:27milestones. What is less well recognized
- 00:13:30is that adolescence also have
- 00:13:32developmental needs. Obviously, they're
- 00:13:34not learning the basic things like
- 00:13:36learning how to walk or talk or bond
- 00:13:38with caregivers, but they are still
- 00:13:40developing. And so, they too are are are
- 00:13:44learning through trial and error.
- 00:13:48During adolescence, um, we build on what
- 00:13:51was the foundation during early
- 00:13:53childhood and we take these principles
- 00:13:55and the learning opportunities and the
- 00:13:57social connections that we make into
- 00:14:01adulthood. Along with a group of um,
- 00:14:04scientists who formed the National
- 00:14:06Scientific Council of Adolescence, folks
- 00:14:08who encompass different areas of
- 00:14:10expertise, we've identified these seven
- 00:14:13developmental needs during adolescence.
- 00:14:16They include exploring the world and
- 00:14:17testing out new ideas and opportunities,
- 00:14:20building decision-making and emotion
- 00:14:22regulation skills. Because although
- 00:14:24there's dramatic growth in areas like
- 00:14:27the prefrontal cortex or emotion
- 00:14:28regulation systems, we need spaces in
- 00:14:31which to practice those skills.
- 00:14:33Adolescence are forming values, goals,
- 00:14:36and identity. It's no coincidence that
- 00:14:38adolescence are often at the forefront
- 00:14:39of new ideas or activism. And at UCLA,
- 00:14:42we certainly saw this last last spring
- 00:14:44and a lot of other places did
- 00:14:46too. Adolescence find meaning and
- 00:14:48purpose through contribution. Contrary
- 00:14:51to the maybe popular narrative that
- 00:14:53adolescence are very inwardly focused,
- 00:14:55it's actually a time in life that when
- 00:14:57they seek out new opportunities to
- 00:14:59contribute to their community and
- 00:15:01contribution has been associated with
- 00:15:04stronger mental
- 00:15:05health. Adolescence continue to need
- 00:15:08support from parents and other caring
- 00:15:10adults. We may assume that adolescence
- 00:15:12start to pay a little bit more attention
- 00:15:14to their friends and their peers, but
- 00:15:16actually they're paying just as much
- 00:15:17attention to those caregivers and adult
- 00:15:20supportive figures who have supported
- 00:15:22them throughout their lives. Adolescence
- 00:15:25are really good at identifying true and
- 00:15:28genuine respect among their peers and
- 00:15:31their adults. And often behaviors that
- 00:15:33we see as risky or ill- advised may be
- 00:15:38enacted because that is one way that
- 00:15:40they find respect among among peers and
- 00:15:43adults. And finally, I won't have much
- 00:15:46opportunity today or time to talk about
- 00:15:48sleep, but that's an area of research
- 00:15:50I've been really interested in in the
- 00:15:52past 10 years or so. And I know that um
- 00:15:55um uh Professor Per will be talking
- 00:15:57about sleep in in his address, so I
- 00:15:58won't talk about it here. And a few
- 00:16:00years ago, the keynote was Matt Walker
- 00:16:01who talked a lot about sleep. But I
- 00:16:03cannot underscore how important sleep is
- 00:16:05for the development of all of these
- 00:16:07milestones and key uh cognitive needs
- 00:16:10that adolescence face during this
- 00:16:13time. Brain development is necessary for
- 00:16:16supporting these specific or adolescent
- 00:16:19specific developmental needs. And when I
- 00:16:22speak to to folks who don't study brain
- 00:16:24development, they often ask,"Well, what
- 00:16:26does it mean that brain development
- 00:16:27keeps happening during adolescence? Does
- 00:16:30it mean that the brain continues to grow
- 00:16:31in size?" And that's not what we mean.
- 00:16:33What we mean is that there's refinement
- 00:16:35of the brain during this time. Sarah
- 00:16:38Jane Blakemore gave a terrific keynote a
- 00:16:40few years ago at this conference, and
- 00:16:42she described the the the particulars of
- 00:16:45what happens in brain development during
- 00:16:47adolescence. So, I'll just briefly
- 00:16:48review it here.
- 00:16:51One is that brain development is
- 00:16:53organized and sequential. And what I
- 00:16:56mean by that and as shown through this
- 00:16:58this video is that the the different
- 00:17:00loes of the brain roughly speaking
- 00:17:03develop from the back to the front. And
- 00:17:05that makes perfect sense. The brain is
- 00:17:06efficient across evolution. The things
- 00:17:09that happen in the back of the brain you
- 00:17:11need right when you're born. the things
- 00:17:12that happen in the front of the brain
- 00:17:14like cognition or future orientation or
- 00:17:16planning for the future perhaps you
- 00:17:18don't need right away when you're born
- 00:17:20because our parents do a really good job
- 00:17:22of scaffolding those cognitive skills
- 00:17:24for us. But during adolescence is when
- 00:17:26we continue to define those higher
- 00:17:28cognitive
- 00:17:30abilities. The second thing that happens
- 00:17:33is that there's refinement of brain
- 00:17:35connectivity. That means that brain
- 00:17:37regions begin are better able to
- 00:17:39communicate with each other and that's
- 00:17:41emblematic of the connections that we're
- 00:17:43making outside of our brain in in our
- 00:17:45community in our schools with our
- 00:17:47families. And this refinement of brain
- 00:17:50connectivity has been the focus of a lot
- 00:17:51of research in um adolescent
- 00:17:54neuroscience because we recognize that
- 00:17:55this affords new cognitive skills,
- 00:17:58faster speed of processing or the
- 00:18:00ability to um to have better connections
- 00:18:02between cognition and emotion.
- 00:18:07There's also significant brain
- 00:18:09plasticity and certainly I don't need to
- 00:18:11share with this group the importance of
- 00:18:12brain plasticity and how our brains are
- 00:18:15reactive to the environment around us
- 00:18:17that our brains unfold in particular
- 00:18:19ways but that doesn't happen in a vacuum
- 00:18:22that the environment and the experiences
- 00:18:24that we have have a huge role in
- 00:18:27scaffolding that sensitivity to the to
- 00:18:29the changing environment.
- 00:18:31This is a image from um a dendrite that
- 00:18:35was provided to me by Linda Wilra at UC
- 00:18:37Berkeley and she studies uh plasticity
- 00:18:40in the adolescent rodent brain and so
- 00:18:42she can provide some insights that of
- 00:18:44course we can't get in in human
- 00:18:46research. But what this video is
- 00:18:48intended to show is that there's very
- 00:18:50dynamic changes in the bhutons that come
- 00:18:52off the the the spine and that happens
- 00:18:54dynamically obviously and in response to
- 00:18:56new
- 00:18:57experiences. Here's a cartoon image that
- 00:19:01um Dr. Wilt has generated showing that
- 00:19:04at any given moment we are both gaining
- 00:19:06connections and losing connections. And
- 00:19:09that's one of the key hallmarks of
- 00:19:10adolescent brain development that in
- 00:19:12response to the environment we may be at
- 00:19:14in one moment pruning away synapses that
- 00:19:16no longer serve us because our the job
- 00:19:18of the of the brain during this time is
- 00:19:20to refine and strengthen those
- 00:19:22connections that are relevant. In
- 00:19:24earlier life that may be strengthening a
- 00:19:26language for a particular lang for the
- 00:19:29language that of of of your parents. Um
- 00:19:32but in adolescence that may mean honing
- 00:19:34a particular skill. We take in a lot of
- 00:19:36skills during adolescence. Social
- 00:19:38skills, driving skills, um abstract
- 00:19:41algebra skills, all of those things are
- 00:19:43new and our brains need to be able to
- 00:19:45respond to it.
- 00:19:47So at the microscopic level, our brain
- 00:19:49cells are literally reaching out for new
- 00:19:51information. And that's why I personally
- 00:19:53find adolescence so fascinating that
- 00:19:55there's no greater time in life or it's
- 00:19:57maybe the last time in life when our
- 00:19:59brains are so dynamic in reaching out
- 00:20:01and seeking out that new
- 00:20:03information. When our spines receive new
- 00:20:06information, they form connections with
- 00:20:07other
- 00:20:09neurons. And this is specific to
- 00:20:11adolescence. Around puberty, our neurons
- 00:20:14can gain and lose about 25% of our
- 00:20:16connections each week. And this drops to
- 00:20:19about 10% by the time we reach
- 00:20:21adulthood. And I only illustrate this
- 00:20:23fact to show that there's a significant
- 00:20:25shift in brain plasticity later in life
- 00:20:28at the microscopic
- 00:20:31level. So back to this question of what
- 00:20:33we can learn from adolescence. I'll
- 00:20:35synthesize some research u for each of
- 00:20:37these points. Before I do, I I want to
- 00:20:41make the point that although we speak
- 00:20:43about adolescence in generalities and
- 00:20:45certainly we need to do so when speaking
- 00:20:47to
- 00:20:47non-scientists, I recognize the vast
- 00:20:50variation in individual differences in
- 00:20:52young
- 00:20:53people. I often show this slide because
- 00:20:55I think it nicely illustrates how people
- 00:20:58who are the same age and the same grade
- 00:21:00as they are in this image um can look so
- 00:21:02different and in turn receive many
- 00:21:05different inputs from the environment.
- 00:21:07Does anyone want to guess how old these
- 00:21:09kids are? They're all the same
- 00:21:14age.
- 00:21:1613,
- 00:21:1812, 10. Okay. What grade are they
- 00:21:23in? Ninth grade, sixth grade. No one has
- 00:21:27ever gotten this right. It's remarkable.
- 00:21:29Even people who study adolescence, all
- 00:21:31of these kids are 14-year-old eighth
- 00:21:33graders. And I really appreciate that
- 00:21:36because the boys on the far right could
- 00:21:39not look more different. The boy on the
- 00:21:40far right in the blue looks like he's in
- 00:21:43high school and the one next to him
- 00:21:44looks like he's in, you know, six. And
- 00:21:47so this just illustrates that when we do
- 00:21:51our imaging studies or when we talk to
- 00:21:54policy makers, we're we're treating
- 00:21:55everybody all 14y olds the same, but
- 00:21:57obviously they are so different. and
- 00:21:59puberty. And this is where biology can
- 00:22:01really tell us or why we need to keep in
- 00:22:03mind that adolescence is um is not
- 00:22:08devoid of the input of of biology. So I
- 00:22:12say this but and please take all the
- 00:22:13research with a grain of salt when we
- 00:22:15group everybody together for for the
- 00:22:17purposes of comparing adolescence for
- 00:22:19adults to adults for
- 00:22:21example. So what can we learn from
- 00:22:24adolescence? One thing I learned and I
- 00:22:26keep in mind and I probably study
- 00:22:27adolescence because I greatly enjoyed
- 00:22:29being an adolescent was um the
- 00:22:32importance of embracing joy that when ha
- 00:22:35when you have an overactive or
- 00:22:37hyperactive or sensitive reward system
- 00:22:39your brain is paying attention to those
- 00:22:41rewards and in a second I'll talk about
- 00:22:43why that's adaptive and
- 00:22:45important. This is a summary image of a
- 00:22:47lot of research we've done in our lab
- 00:22:49and labs around the world to examine the
- 00:22:51reward system in adolescence. When I was
- 00:22:54a a graduate student at BJ Casece, there
- 00:22:56was actually really very little known
- 00:22:58about the adolescent brain and that
- 00:23:00surprised us when we started to dig into
- 00:23:02the literature. We learned that there
- 00:23:03was a lot of understanding of what
- 00:23:05happens in earlier life or what happens
- 00:23:07in adults or even college students. But
- 00:23:09what makes adolescence so sensitive to
- 00:23:11reward? At least that was our anecdotal
- 00:23:13understanding of adolescence.
- 00:23:16And and indeed when we threw adolescence
- 00:23:20into the sc not threw we put we nicely
- 00:23:22asked them to come into the scanner for
- 00:23:24us and we put them in the scanner and we
- 00:23:26showed them images of money or the
- 00:23:28opportunity to earn money or in a
- 00:23:30subsequent study I I gave them primary
- 00:23:33rewards or we gave them social rewards.
- 00:23:36They all yield activation in in dopamine
- 00:23:40rich regions like the stridum. And this
- 00:23:41is a study or a finding that's been
- 00:23:43consistently shown. And interestingly,
- 00:23:46even when given the same experience in
- 00:23:48the in the scanner, the adolescence show
- 00:23:50an exaggerated response. And so that
- 00:23:53told us a little bit about how what the
- 00:23:55brain is paying attention to during the
- 00:23:56adolescent years. And later led to
- 00:23:59questions about well why would that make
- 00:24:01sense for us to have a time in life when
- 00:24:03we are more sensitive to the rewards in
- 00:24:05our environment.
- 00:24:07Mechanistically, we obviously cannot put
- 00:24:10in um electrodes into the human
- 00:24:12adolescent to to test the hypothesis
- 00:24:15that perhaps they have more dopamine
- 00:24:17sensitivity because that was the obvious
- 00:24:19answer to that and especially there were
- 00:24:20a lot of studies at that time showing
- 00:24:22that dopamine sensitivity led to greater
- 00:24:25reward sensitivity.
- 00:24:27But luckily we have um colleagues who do
- 00:24:30research in in rodent models who can
- 00:24:32shed some light on that and and in um
- 00:24:35and non-human primate models. And the
- 00:24:38basic story is that if you compare um
- 00:24:40dopamine release or the synaptic
- 00:24:42vesicles or the availability of dopamine
- 00:24:44receptors in in human ver and I'm sorry
- 00:24:47in rodent adults versus rodent
- 00:24:49adolescence, there's simply just more
- 00:24:51greater dopamine sensitivity in the
- 00:24:53adolescent brain. I found that
- 00:24:55fascinating because around the same time
- 00:24:58there was a lot of research by Wol from
- 00:25:00Schultz's group showing that dopamine
- 00:25:03did more than code rewards or recognize
- 00:25:05rewards. But in fact, dopamine was
- 00:25:07critical for learning about the
- 00:25:09environment. And that makes perfect
- 00:25:11sense if you have a group of individuals
- 00:25:13who are learning a whole new social
- 00:25:15landscape as they transition into
- 00:25:16adulthood.
- 00:25:18That research was done by Wolram Schultz
- 00:25:20and his colleagues in non-human primates
- 00:25:23whereby they would stick an electrode
- 00:25:25into their brain and were able to
- 00:25:27monitor how dopamine acquire helped
- 00:25:29acquire new learning or helped um with
- 00:25:32the acquisition of how a behavior right
- 00:25:35now would impact an outcome
- 00:25:37later. And those of you who were reading
- 00:25:40this literature at the time in 2003,
- 00:25:43Ferrell and colleagues published this
- 00:25:45very seinal paper showing that dopamine
- 00:25:47was coding learning in the brain. That
- 00:25:50is if you gave a monkey a cue with
- 00:25:51different v um very um varying levels of
- 00:25:55probability that the dopamine would kind
- 00:25:57of stay enga the dopamine neurons would
- 00:25:59stay engaged until they learned about
- 00:26:01that outcome.
- 00:26:02Um, this is really intriguing to me
- 00:26:04because at that point I really had a
- 00:26:06pretty simplified view of the reward
- 00:26:09system in the brain and thought it was
- 00:26:10really simply just coding for for
- 00:26:12reward.
- 00:26:13I shared this at a at a talk and um
- 00:26:16Daphnes Johanni who's a colleague at
- 00:26:18Colombia who who didn't study
- 00:26:20adolescence but she studied the um
- 00:26:22learning systems in the brain and
- 00:26:24dopamine in adults um asked if I would
- 00:26:27want to partner with her and test the
- 00:26:29hypothesis that because the adolescent
- 00:26:31brain is more sensitive in these
- 00:26:32misolyic systems perhaps not only did it
- 00:26:35make adolescence more sensitive to
- 00:26:36reward but also conferred benefits in
- 00:26:39learning behavior and that's exactly
- 00:26:41what we found. I'm not going to go
- 00:26:43through the details of this study, but
- 00:26:45suffice it to say that we asked
- 00:26:46participants, adults and and adolescence
- 00:26:50to perform a very simple probabilistic
- 00:26:52learning task. And over time, what we
- 00:26:55found is that even though the
- 00:26:57adolescence and the adults showed
- 00:26:58similar learning accuracy early in the
- 00:27:01study, by the end of the experiment, the
- 00:27:03adolescence were outperforming the
- 00:27:05adults. And this was work done by Juliet
- 00:27:07Davadau when she did a mini sobatical
- 00:27:09from graduate school at Columbia and
- 00:27:10came to UCLA and collected these
- 00:27:13data. Juliet also found that this
- 00:27:16greater outperformance of adolescence
- 00:27:19compared to adults in learning was
- 00:27:21accompanied by greater prediction error
- 00:27:23related activation in these learning
- 00:27:25systems both in the hippocampus and in
- 00:27:29the stratum. And furthermore that
- 00:27:32connectivity among these stridal and um
- 00:27:36hypocample systems or regions in the
- 00:27:38brain conferred greater uh memory
- 00:27:42positivity bias in the adolescence
- 00:27:44whereby this stronger connectivity in
- 00:27:46the hippocampus and the stridum was
- 00:27:48associated with a a greater memory bias
- 00:27:50in the adolescence if they had been
- 00:27:52positively rewarded. So here's where
- 00:27:54that reward sensitivity comes in and it
- 00:27:57supports and and and amplifies the
- 00:27:59learning that adolescence do compared to
- 00:28:01adults. And again coming back to the e
- 00:28:03ecological validity of that it makes
- 00:28:06perfect sense because as adolescence
- 00:28:08we're faced with a lot of new
- 00:28:09situations, a lot of new social
- 00:28:10interactions, new skills that we're
- 00:28:12learning. And so it makes sense that we
- 00:28:14have a system that supports learning
- 00:28:16those new bits of information.
- 00:28:20This was supported also by research in
- 00:28:22Holland by Eveina Cone who's done a lot
- 00:28:25of this research also showing that
- 00:28:27increased rial sensitivity in
- 00:28:28adolescence benefits learning and um Dr.
- 00:28:32Cronhn's work has and has shown this in
- 00:28:34all types of learning, cognitive
- 00:28:35learning, social learning um in ways
- 00:28:37that that support this notion that it's
- 00:28:40not a coincidence that adolescence has
- 00:28:43this period in life when we have greater
- 00:28:44sensitivity in the very systems that
- 00:28:47help us identify rewards that we should
- 00:28:49orient towards and also support
- 00:28:52learning. And by the way, humans are not
- 00:28:55the only ones who show this these
- 00:28:56changes during adolescence. Most species
- 00:28:59on Earth have an adolescent period of
- 00:29:01life when individuals take greater risks
- 00:29:04when they're seeking out new social
- 00:29:06structures. And all animals do what
- 00:29:09adolescence or human humans do during
- 00:29:11adolescence. They spend more time
- 00:29:13socializing with their peers. They
- 00:29:16squabble with adults. They eat more
- 00:29:18food. And they fumble through a new
- 00:29:20social landscape. Because becoming an
- 00:29:22adult doesn't happen overnight. It
- 00:29:25requires learning. It requires
- 00:29:26mimicking. And whether you're a kitten
- 00:29:28or a puppy or human adolescent, becoming
- 00:29:31an adult takes time, experience, and
- 00:29:33learning. And it's for this very reason
- 00:29:36that the adolescent brain is so special
- 00:29:38because it's literally the bridge that
- 00:29:40helps kids enter into the next dimension
- 00:29:42of life. And when we do that, we're not
- 00:29:46always smooth when we're transitioning
- 00:29:48into adulthood. And we're often
- 00:29:50mimicking the social behaviors of of
- 00:29:52adults. um similar to the ways in which
- 00:29:55babies make the the the behaviors of of
- 00:29:58those around them. I'm going to show you
- 00:30:00a video from released when the book
- 00:30:03Wildthood was released uh a few years
- 00:30:05ago and it kind of illustrates the
- 00:30:08social mimickry that that needs to
- 00:30:09happen during adolescence and I find it
- 00:30:11really
- 00:30:16charming. Look at these albatross.
- 00:30:18They're masters of this courtship dance.
- 00:30:21They're in sync. They're looking at each
- 00:30:25other.
- 00:30:28Okay? So, they're using it to assess
- 00:30:30each other's suitability as partners.
- 00:30:32Okay? They're beautiful when they're
- 00:30:33doing it. Now, you're going to see the
- 00:30:34teenagers doing
- 00:30:38it. They're not looking at each other.
- 00:30:40They're going in each different
- 00:30:42direction. They're doing it by the side
- 00:30:44of the road. Like,
- 00:30:48and I love this so much because we do
- 00:30:52the same thing as humans, right? We see
- 00:30:54in here they learn these moves by
- 00:30:57watching the more mature adults. Our
- 00:30:59behaviors are mimicked by adolescence.
- 00:31:02I'm often asked about how bad is social
- 00:31:04media for young people. Maybe they
- 00:31:06shouldn't be doing it. Well, then maybe
- 00:31:07we shouldn't be doing it because that's
- 00:31:09what young people are doing is mimicking
- 00:31:11their parents. And this is the the book
- 00:31:12is this wonderful book by Barbara Nat
- 00:31:15Heroets if you're interested about um
- 00:31:18the journey that adolescence make into
- 00:31:23adulthood. The second thing we can learn
- 00:31:26from adolescence is how to prioritize
- 00:31:28social connections. Um they're really
- 00:31:31good at it and sometimes they we kind of
- 00:31:34get them in trouble for doing it. the
- 00:31:36the social connections that they are
- 00:31:38doing during this time are um or the
- 00:31:42maturing connections in their brain are
- 00:31:44reflective of the ongoing connections
- 00:31:46they're making with their peers, with
- 00:31:47their families, and with their
- 00:31:49communities. We've recently done some
- 00:31:51research to examine the the attributes
- 00:31:53or the benefits of of pro-social
- 00:31:55behavior.
- 00:31:57What you're seeing here are data from a
- 00:31:59study in which we collected um
- 00:32:01information from about 270 adolescent
- 00:32:03270 adolescents ages 9 to 15 and a group
- 00:32:07of of young adults and they did a simple
- 00:32:10decision-making task where they were
- 00:32:12trying to earn money for either
- 00:32:13themselves or someone in their family, a
- 00:32:16friend or a stranger. So for example,
- 00:32:19they would choose whether or not to lose
- 00:32:22a $1.50 50 in favor of their mom earn
- 00:32:25ear earning $3. These are very common
- 00:32:28pro-social tasks that are used to assess
- 00:32:30how people make decisions when it's
- 00:32:31going to benefit them versus benefit
- 00:32:32someone else. And what we found
- 00:32:35unsurprisingly is that costly giving
- 00:32:38that is giving up money for yourself in
- 00:32:40for someone else um varied as a function
- 00:32:43of age and that uh it different it was
- 00:32:47differentiated based on who the target
- 00:32:49was whether it was a family member, a
- 00:32:50friend or a stranger.
- 00:32:53What a little bit surprised us is that
- 00:32:55the family the person the family person
- 00:32:58received um the most costly given
- 00:33:00behavior by the ad by the adolescent
- 00:33:02regardless of age and this actually
- 00:33:04increased as young people became
- 00:33:05adolescence and increased into the early
- 00:33:07adulthood
- 00:33:09age. There was significant activation in
- 00:33:12regions that as Sarah Jane Blakemore
- 00:33:14described are considered the social
- 00:33:15brain that help us identify the feelings
- 00:33:18of others or take the perspective of
- 00:33:19other people. In this case, we found um
- 00:33:22significant uh age related differences
- 00:33:24in the dorsal prefrontal cortex when
- 00:33:27giving by age where there was an
- 00:33:29increase during the late adolescent
- 00:33:30years that that tapered off. So the
- 00:33:34systems that are ongoing maturation
- 00:33:36during adolescence are showing that or
- 00:33:38paying the most attention to who they
- 00:33:40are giving to and um and engaging these
- 00:33:43systems the most. And again, this is um
- 00:33:46consistent with research on um neural
- 00:33:50systems that that um became more engaged
- 00:33:52during their adolescent
- 00:33:56years. Um the last thing I'll say is
- 00:34:00about what we can learn from adolescence
- 00:34:01is how they make strategic risks. When
- 00:34:05we talk about adolescence or the the
- 00:34:07media speaks about risk takingaking in
- 00:34:08adolescence, they're often thinking
- 00:34:10about this kind of risk- takingaking.
- 00:34:12Maybe risk takingaking that is ill ill-
- 00:34:14advised or may cause harm to the self or
- 00:34:16other. But when I think about
- 00:34:18risk-taking, I think about or during
- 00:34:20adolescence, I think about how adaptive
- 00:34:22it is for the adolescent that if they're
- 00:34:24engaging in a risk, it may be adaptive
- 00:34:27for that person to gate social status to
- 00:34:30uh form a social bond or to leave the
- 00:34:32nest so to speak. And so often
- 00:34:35adolescence, as I mentioned before, are
- 00:34:37trying out new things. Maybe they're
- 00:34:39speaking on behalf of a cause they
- 00:34:41believe in or trying out for new sports
- 00:34:43or engaging in volunteer experiences. As
- 00:34:46adults, we may not see this as
- 00:34:47risk-taking, but all of those are
- 00:34:49formative experiences that help shape
- 00:34:51who they are and are supported by
- 00:34:54enhancement of the misolyic system that
- 00:34:57is oriented towards
- 00:34:59risk-taking. We did a study a few years
- 00:35:02ago. It was a graduate student Emily
- 00:35:04Barkley Levenson who was interested in
- 00:35:06understanding whether or not adolescence
- 00:35:08are good at identify advantageous versus
- 00:35:11disadvantageous risks. And so she used
- 00:35:14um a task that had previously been
- 00:35:17published by Russ PDRA called the mixed
- 00:35:19gambles task in which adolescence are
- 00:35:22given a simple pie chart and asked is
- 00:35:24this a risk you would be willing to
- 00:35:25take? And based on the expected value of
- 00:35:28each of those combinations of of the
- 00:35:30offers they were given, some some um
- 00:35:34risks were advantageous to take, some
- 00:35:36were disadvantageous, and some were
- 00:35:38neutral. So it looked a little bit like
- 00:35:41this, not a little bit. This is exactly
- 00:35:42what it looked like. So um they were
- 00:35:45either made in this case in the upper
- 00:35:46left, this was a disadvantageous risk
- 00:35:49because you were gambling on winning
- 00:35:50eight dollars or $6 versus losing losing
- 00:35:5318. an advantageous risk might offer
- 00:35:57gaining $17 versus losing five and a
- 00:36:00neutral risk was was um had
- 00:36:02parody. And what we found behaviorally
- 00:36:06is that when we plotted out the expected
- 00:36:08value of each of these gamles and
- 00:36:11compared adolescence and adults who were
- 00:36:13receiving an fMRI scan, there was no
- 00:36:15difference in the choices they made when
- 00:36:17the risks were at
- 00:36:18disadvantageous. So that told us a few
- 00:36:20things. Um one, the task was working.
- 00:36:23the ad the all the participants were
- 00:36:25able to identify the distinction among
- 00:36:27these different gamles they were offered
- 00:36:29that contrary to maybe popular belief
- 00:36:32adolescence were not more willing to
- 00:36:33take this advantageous
- 00:36:36risks. There was no difference in the
- 00:36:38neutral behavior but differences emerged
- 00:36:40when participants were presented with an
- 00:36:43advantageous risk and in this case the
- 00:36:45adolescence were better able at
- 00:36:47endorsing taking an advantageous risk as
- 00:36:49compared to the adults. Obviously, these
- 00:36:52are very different types of risks than
- 00:36:53they face in the real world. But to us,
- 00:36:55it gave us some insight into how the
- 00:36:57brain is responding to um risks that are
- 00:37:00presented to them. And also that
- 00:37:02adolescence were were in at least in
- 00:37:04this house better able than adults to
- 00:37:06identify them.
- 00:37:08when they were taking these advantageous
- 00:37:10risks, the adolescence showed greater
- 00:37:12engagement of these same systems that
- 00:37:14I've previously mentioned as engaging
- 00:37:16during social rewards or or um other
- 00:37:19types of of monetary rewards.
- 00:37:23So we can learn a few things from
- 00:37:25adolescence and I find this work
- 00:37:28continue to find this work really
- 00:37:29interesting but also have started to
- 00:37:32think how we can use the science to
- 00:37:34inform policies and programs that impact
- 00:37:36adolescence because we've let science
- 00:37:38sit on the shelf then then maybe it
- 00:37:42wasn't as impactful as we as we think it
- 00:37:44it was. Um at the center for the
- 00:37:47developing adolescent which I run with
- 00:37:48my colleague Andrew Fellini we've
- 00:37:51learned a lot. We're not policy makers.
- 00:37:53We're not legal scholars. But we've
- 00:37:55learned that communication to these
- 00:37:56spaces are really important for us to
- 00:37:58translate what we think is the most
- 00:38:00important aspects of of the science we
- 00:38:02do, which is on adolescence. And so we
- 00:38:05work hard to build this this um
- 00:38:09birectional communication among among um
- 00:38:13communicators, among policy makers, and
- 00:38:15of course among
- 00:38:17scientists. And this has led to some
- 00:38:20research to some to some work that has
- 00:38:22impacted um spaces that are not just in
- 00:38:25the laboratory. This is an amicus brief
- 00:38:27that a few of us signed on to um a few
- 00:38:30years ago in in Miller v. Alabama. Um
- 00:38:33and developmental science provides
- 00:38:35concrete evidence to support the
- 00:38:37argument that juveniles warrant
- 00:38:39different treatment in the justice
- 00:38:40system than do adults.
- 00:38:42Many other um adolescent neuroscientists
- 00:38:44have have um been in communication with
- 00:38:47legal scholars about this. But it really
- 00:38:50is remarkable how much of an impact
- 00:38:52science can have when we are open to the
- 00:38:55communication with folks who who have
- 00:38:57not been coming to conferences like we
- 00:38:59are um and understanding the the
- 00:39:01benefits and the ramifications of of the
- 00:39:04methods that we use.
- 00:39:08Um this kind of work in neuroscience and
- 00:39:11developmental psychology has led to
- 00:39:12several different Supreme Court rulings
- 00:39:15and ration um a lot of them have been
- 00:39:17centered on the understanding that the
- 00:39:20brain continues to develop during
- 00:39:21adolescence that it is plastic that
- 00:39:24there's a differences in peer influence
- 00:39:27during the adolescent per during the
- 00:39:29adolescent period um and it has led to
- 00:39:32some significant changes in how we treat
- 00:39:34young people in the justice system and
- 00:39:35this I just highlight this as one
- 00:39:36example because obviously ly many
- 00:39:38different spaces educational system
- 00:39:40impacted um can have an impact but the
- 00:39:43justice system is one that has stood
- 00:39:44out.
- 00:39:47um uh colleagues of ours uh BJ Casey, uh
- 00:39:50S Leah Somerville, Ariel Baskin Robbins
- 00:39:54nicely synthesized this research a few
- 00:39:56years ago and the the studies I or the
- 00:40:00Supreme Court rulings listed in this
- 00:40:01table are all for young people under the
- 00:40:04age of 18, but we know that the brain
- 00:40:06continues to mature beyond 18. And so in
- 00:40:09this review they made the case that
- 00:40:11psychological and neuroscientific
- 00:40:13evidence for expanding the age of
- 00:40:15youthful
- 00:40:17offenders. They relied on terrific work
- 00:40:19by um Alli Cohen published in 2016. And
- 00:40:24this study was really important because
- 00:40:26it it addressed an issue that is often
- 00:40:28asked of those of us who testify before
- 00:40:31different judges or in criminal cases
- 00:40:33where they ask a simple question. When
- 00:40:36is an adolescent an adult? And we may
- 00:40:39take for granted, right, as scientists,
- 00:40:40we kind of have these age age bins. Um,
- 00:40:45in adolescent research, it's often based
- 00:40:46on the age of majority, which is age 18
- 00:40:48in this country. But the study examined
- 00:40:51whether there are differences in
- 00:40:53cognitive ability or performance in
- 00:40:56emotional versus non-emotional context.
- 00:40:58This was funded by the MacArthur
- 00:40:59Foundation um in a in some efforts that
- 00:41:03aimed to to to merge neuroscience with
- 00:41:06um with re with um policy um
- 00:41:11initiatives. And what Ally and her
- 00:41:13colleagues found is that under um
- 00:41:17non-threatening environments and very
- 00:41:18cold cognitive environments, there were
- 00:41:21distinctions in cognitive performance
- 00:41:23among adolesccents ages 13 to 17, young
- 00:41:27adults ages 18 to 21 and um individuals
- 00:41:31between the ages of 22 to 25. There was
- 00:41:34a linear increase in their cognitive
- 00:41:35performance.
- 00:41:37However, they included a manipulation in
- 00:41:40the task whereby these individuals were
- 00:41:42making cognitive um choices under
- 00:41:45emotional um context or or threat. And
- 00:41:49here you start to see a difference in
- 00:41:51the ways in which people make cognitive
- 00:41:53choices. And now the young adult group
- 00:41:56looked more similar to the adolescent
- 00:41:58group as compared to the 22 to 25 year
- 00:42:01olds. This is really important research
- 00:42:03because sometimes I think we take for
- 00:42:05granted um the distinct nuance in
- 00:42:08developmental um maturation that again
- 00:42:11we as scientists may take for granted
- 00:42:13but is very important in in decisions
- 00:42:16related to policies related to young
- 00:42:18people.
- 00:42:20This research was really important for
- 00:42:23um a recent and it's nice that we're in
- 00:42:25Massachusetts um last year showing that
- 00:42:28the m Massachusetts Supreme Court ruled
- 00:42:30against life without parole parole for
- 00:42:32emerging
- 00:42:33adults. The court's decision was
- 00:42:35influenced in part by a comprehensive
- 00:42:37review of scientific research on brain
- 00:42:39development. And this is the collective
- 00:42:42work of so many people who have taken
- 00:42:44their cognitive neuroscience research
- 00:42:46and and amplified it and communicated it
- 00:42:48to to folks outside of the of the lab. I
- 00:42:51testified in this court and I have to
- 00:42:53say one of the most gratifying things
- 00:42:55I've ever experienced in my career was
- 00:42:57this text message. Um this is from the
- 00:42:59lawyer with whom I worked on this case
- 00:43:01and he said we won. Yay. No life without
- 00:43:04pearl for 18 19 20 year olds in
- 00:43:06Massachusetts. Over 200 people have you
- 00:43:08to thank for a chance of freedom. Ryan
- 00:43:10and I are going to the prison blah blah
- 00:43:11blah to tell our client. But it's um
- 00:43:14it's just a reminder to me sometimes we
- 00:43:16get stuck in our in our research uh labs
- 00:43:20and the details of an experiment or how
- 00:43:23we're going to submit a grant or write a
- 00:43:25paper. Um but people are paying
- 00:43:27attention. What we write in our
- 00:43:28discussion sections makes a lot of has a
- 00:43:31big impact in the ways in which those
- 00:43:33data are interpreted.
- 00:43:36Um so I mentioned earlier that at the
- 00:43:38center for the developing adolescent we
- 00:43:40aim to translate the science of
- 00:43:42adolescence into um spaces that are not
- 00:43:46for people who are not as versed in
- 00:43:47science. We do this a few ways. We've
- 00:43:50recently launched what's called steps
- 00:43:52for youth. It's an initiative that
- 00:43:55translates science to enhance policy
- 00:43:57success. We also provide um briefs for
- 00:44:01folks who are interested in various
- 00:44:03topics about how for example um
- 00:44:06anti-black race racism impacts
- 00:44:09development, social media impacts
- 00:44:11development, the importance of
- 00:44:13contribution during
- 00:44:14adolescence and we also um speak to
- 00:44:17various groups. We partner with TED to
- 00:44:20describe the science of adolescence. And
- 00:44:22I only display all this because when I
- 00:44:25was a graduate student, I never felt
- 00:44:27like it would be I honestly thought it
- 00:44:29was important or I could have something
- 00:44:30to say. But realizing how important this
- 00:44:33is has been uh a really important part
- 00:44:35of of the research I've I've been
- 00:44:39doing in all of these spaces. We also
- 00:44:41remind folks that the impact of lived
- 00:44:44experience, the the impact that lived
- 00:44:46experience has on adolescent brain
- 00:44:47development. We know that social
- 00:44:49structures and systems can support or
- 00:44:51challenge positive development. That
- 00:44:54communities and cultural practices
- 00:44:55support development. Um and finally that
- 00:44:59early life adversity can have a
- 00:45:00significant impact on young people even
- 00:45:02if it happens early in life that
- 00:45:04ramifications can be observed in
- 00:45:06adolescence. But again the beauty of
- 00:45:08adolescence is that the plasticity can
- 00:45:10help redirect those impacts of early
- 00:45:11life adversity.
- 00:45:14So I'll just end by giving or offering
- 00:45:17some thoughts about how we can support
- 00:45:19and continue to support the developing
- 00:45:20brain. And the first is that we can
- 00:45:22celebrate adolescence that we can move
- 00:45:24away from a narrative that pathologizes
- 00:45:26period of life that is so normative that
- 00:45:28is not only unique to to humans and that
- 00:45:31is necessary for our transition to
- 00:45:33adulthood. We can invest in frameworks
- 00:45:35that recognize the whole person. We
- 00:45:37obviously do not develop in a vacuum.
- 00:45:40And so all of the the spaces in which
- 00:45:42adolescence are reared matter for who
- 00:45:44they
- 00:45:45are. That we can provide adolescence
- 00:45:48with opportunities to contribute and to
- 00:45:50develop their identities because that
- 00:45:52often they they may be changing during
- 00:45:54this time, but that is all part of the
- 00:45:56the trial and error learning that
- 00:45:57happens during this period of
- 00:45:59life. We can support the inherent
- 00:46:02adolescent need to collaborate and to
- 00:46:05learn through social means. Um it's no
- 00:46:08coincidence that they like to spend time
- 00:46:09with their peers offline and and online.
- 00:46:12Um and that's because they are also
- 00:46:13learning the social rules that will help
- 00:46:15them transition into
- 00:46:17adulthood. And we can amplify their
- 00:46:19positive experiences and promote their
- 00:46:21health. There there's a lot of
- 00:46:23discussion, rightfully so, about mental
- 00:46:25health during adolescence, particularly
- 00:46:27after the pandemic. But adolescence are
- 00:46:29not only their mental health. Um, Andrew
- 00:46:31and I wrote a a recent article, a
- 00:46:34relatively recent article, um, calling
- 00:46:36for the need for young people to
- 00:46:38experience to have experiences that
- 00:46:40boost their their mental health that
- 00:46:42rather than reacting to to mental health
- 00:46:44challenges, perhaps we can support them
- 00:46:46before then because we know that there
- 00:46:48are a lot of things we can put in place
- 00:46:49to support that. that is volunteering
- 00:46:52experiences, good sleep as I mentioned,
- 00:46:54um supportive environments or
- 00:46:56relationships with with caregivers, all
- 00:46:59of those things support mental health
- 00:47:01before it becomes a
- 00:47:02challenge. And with that, I will end. Um
- 00:47:05thank my lab members, current and
- 00:47:08former, my collaborators, my funding
- 00:47:10source, um and also those uh who support
- 00:47:13our work at the center for the
- 00:47:14developing adolescent. And thank you
- 00:47:17[Applause]
- 00:47:27Do it. Do it.
- Cognitive Neuroscience Society
- Adolescent Brain Development
- Keynote Address
- Michael Anderson
- Sabina Castner
- Adriana Galvan
- Neuroscience Research
- Social Connections
- Developmental Needs
- Policy Impact