Lipids

00:07:04
https://www.youtube.com/watch?v=VGHD9e3yRIU

Resumen

TLDRThe podcast by Mr. Andersen explores lipids, highlighting triglycerides, phospholipids, and cholesterol's role in our bodies. Triglycerides, common fats in butter and olive oil, consist of a glycerol head and three fatty acid tails rich in energy due to their carbon-hydrogen bonds. Lipids not only store energy but also form cellular membranes. Phospholipids have a glycerol head connected to two fatty acid tails, playing a critical role in cell membrane structure where cholesterol maintains membrane fluidity. Saturated fats, solid at room temperature, have carbon atoms fully bonded to hydrogen, whereas unsaturated fats have kinks due to double bonds, making them liquid at room temperature. Human innovations, like converting liquid vegetable oil into solid margarine, mimic these structures. Olestra was introduced as a fat-free alternative that provides the texture and flavor of fats without being digested, but posed health issues. Overall, understanding the structure and function of lipids reveals their essential role in energy provision, cellular function, and health implications, including the risks associated with excessive saturated and trans fat consumption.

Para llevar

  • 🧈 Triglycerides are key energy-rich fats found in common foods.
  • 🔍 Lipases break down fats to release stored energy.
  • 🔬 Phospholipids are vital for cellular membrane structure.
  • 🍽️ Saturated fats are solid at room temperature due to straight fatty acid tails.
  • 💧 Unsaturated fats have kinked tails and are liquid at room temperature.
  • 🧪 Hydrogenation converts unsaturated to saturated fats.
  • 🧻 Olestra is a non-digestible fat substitute; can cause digestive issues.
  • ⚖️ Cholesterol helps maintain cell membrane stability.
  • 🔥 Energy in fats stems from hydrocarbons in fatty acid tails.
  • 🚫 Overconsumption of trans fats can lead to health problems.

Cronología

  • 00:00:00 - 00:07:04

    In this podcast, Mr. Andersen discusses lipids, also known as fats, such as those found in butter and olive oil, which are classified as triglycerides. These compounds are composed of a glycerol head and three fatty acid tails, which are energy-rich due to the hydrocarbon bonds. The body uses lipids as a vital energy source by breaking them down with enzymes called lipases during cellular respiration, storing them for future use. Furthermore, lipids contribute to the structural integrity of cell membranes through phospholipids and cholesterol. The former forms the membrane itself, while the latter maintains its fluidity.

Mapa mental

Mind Map

Preguntas frecuentes

  • What are triglycerides?

    Triglycerides are fats found in foods like butter and olive oil, consisting of a glycerol head and three fatty acid tails.

  • How do saturated and unsaturated fats differ?

    Saturated fats have no double bonds and are solid at room temperature, while unsaturated fats have double bonds causing kinks in their structure, making them liquid at room temperature.

  • What is the role of cholesterol in cell membranes?

    Cholesterol helps maintain the fluidity of the cell membrane, keeping it stable under varying temperatures.

  • What problems occurred with olestra-containing products?

    Olestra, a fat substitute, can cause digestive issues and inhibit vitamin absorption because the body lacks the enzymes to break it down.

  • Why are phospholipids important?

    Phospholipids make up cell membranes, providing structure and regulating what enters and exits the cell.

  • What health concerns are associated with saturated and trans fats?

    Saturated and trans fats can lead to health problems like atherosclerosis and heart disease.

  • How are hydrocarbons related to energy in fats?

    Hydrocarbons in fatty acid tails store energy in carbon-hydrogen bonds, which is released during cellular respiration.

  • Why is it important to have some lipids in our diet?

    Lipids are essential for energy, building cell membranes, and acquiring important nutrients like cholesterol.

  • How can unsaturated fats be transformed into saturated fats?

    Unsaturated fats can be hydrogenated to form saturated fats such as margarine.

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  • 00:00:03
    Hi. It's Mr. Andersen and in this podcast I'm going to talk about lipids
  • 00:00:08
    or the fats. The fat that's found in butter or the fat that's found in olive oil is what
  • 00:00:13
    we call a triglyceride. It's basically going to have a head, a glycerol head and then it'g
  • 00:00:18
    going to have three fatty acids tails. And that's where the energy is. And so when we
  • 00:00:22
    eat fat we can break it down. We have enzymes called lipases that are able to break that
  • 00:00:26
    down and then we can get energy from it. And that's been very important. We can store energy
  • 00:00:31
    in fats inside our body and then we can burn them when we need them. But don't forget that
  • 00:00:36
    fats in addition to providing energy also provide the surroundings. And so the cell
  • 00:00:41
    membrane that goes around every cell is made up of phospholipids. And the cholesterol is
  • 00:00:46
    found within the phospholipid by layer and that maintains the fluidity of the cell. And
  • 00:00:52
    so lipids are incredibly important. But where does the energy come from? That comes from
  • 00:00:56
    the hydrocarbons. And so if you look at those fatty acid tails it's essentially a carbon
  • 00:01:01
    attached to a carbon to a carbon to a carbon to a carbon . . . and then it has hydrogen
  • 00:01:10
    around the outside of it. And so we call that a hydrocarbon. And there's energy in those
  • 00:01:15
    bonds. And so gasoline burning out of control or the paraffin wax that's burning in a candle
  • 00:01:21
    is a hydrocarbon. There's a lot of energy between those carbon hydrogen bonds. And so
  • 00:01:26
    there's also a lot of energy found in butter or in olive oil. It's in the bonds between
  • 00:01:31
    the carbon and the hydrogen. And so let's start with a triglyceride. So this is a basic
  • 00:01:35
    fat. The head up here is going to be called the glycerol head and then this is going to
  • 00:01:41
    be the fatty acid tails that go down the end. And so fatty acid tail has so much carbon
  • 00:01:47
    and hydrogen in it that on this diagram we don't even draw them. Each of these points
  • 00:01:50
    represents a carbon, a carbon, a carbon. And then right here we're going to have two hydrogen
  • 00:01:55
    bonds or two hydrogens bonded to each of those carbons. And so you can see that there's a
  • 00:01:59
    huge amount of energy locked within that triglyceride and we can get that out through cellular respiration.
  • 00:02:06
    But know this. Those tails can come in two different forms. We can have what are called
  • 00:02:10
    saturated tails. A saturated tail is going to have hydrogen all the way around the outside.
  • 00:02:16
    And if you have hydrogen all the way around the outside then you're going to be saturated
  • 00:02:21
    with hydrogen. And if you're a saturated fat you're going to be a straight fat. And so
  • 00:02:27
    a triglyceride is going to have three of these fatty acid tails and the glycerol head, but
  • 00:02:32
    if it is saturated all of those are going to be straight. And if they're all straight
  • 00:02:37
    they can pack up on top of other triglycerides. And so saturated fats are normally going to
  • 00:02:42
    be a solid at room temperature. What happens if you don't have hydrogen all the way around
  • 00:02:48
    the outside? You're going to form these double bonds in here. If you have double bonds basically
  • 00:02:53
    what that does is it puts a bend in your tail. And so you're going to have a kinky tail.
  • 00:02:59
    And so if you're a saturated fat, you're going to look like this. If you're an unsaturated
  • 00:03:03
    fat you're going to look like this with kinky tails. And the kinky tails can't quite pack
  • 00:03:07
    together. And so normally fats that are unsaturated are going to be a liquid at room temperature.
  • 00:03:13
    Now humans have figured out how to take, for example, vegetable oil, which is a unsaturated
  • 00:03:19
    fat or it's going to be a liquid at room temperature and we can bubble hydrogen through it. We
  • 00:03:24
    can straighten out those tails and we can make a saturated fat called margarine that's
  • 00:03:29
    going to be a solid at room temperature. We've transformed this fat and if you know anything
  • 00:03:34
    about fats those saturated fats are the ones that are least best for us and can lead to
  • 00:03:41
    arteriolosclerosis, especially trans fats. Example then of how we've tried to get around
  • 00:03:47
    this. And this is a somewhat funny story. This is olestra. Olestra is a fat that was
  • 00:03:51
    made by humans. And so basically what they did us took a normal triglyceride but they
  • 00:03:55
    built it around a sucrose, so they built it around a sugar. And so instead of having just
  • 00:04:00
    three of these fatty acid tails they had sometimes eight, sometimes ten. Sometimes even more.
  • 00:04:06
    What's neat about that is that when you go through your digestive system we don't have
  • 00:04:10
    olestrase. We don't have an enzyme that can break that down and so the olestra moves right
  • 00:04:15
    through our digestive system. So it's a fat that feels like a fat, tastes like a fat but
  • 00:04:20
    it doesn't make us fat. And so Wow chips were introduced I think in the 1990s and had this
  • 00:04:26
    olestra in it. Basically what happened is when people started eating these Wow chips,
  • 00:04:30
    they got incredibly sick. They got cramping and they had to put a warning label on the
  • 00:04:34
    outside that it can lead to loose stools, and it pulls vitamins outside of your body.
  • 00:04:40
    They've kind of refined this since then and so there's not a lot of these adverse reactions.
  • 00:04:46
    I think Pringles light chips still contain olestra in it, but we're tricking our body,
  • 00:04:51
    because our body doesn't have those enzymes. Now I also said there are two more important
  • 00:04:55
    lipids. The first one's called phospholipids. Phospholipids are going to have, you can see,
  • 00:04:59
    two fatty acid tails, but they're going to have a head that contains a phosphate group.
  • 00:05:05
    That phosphate group is going to have a negative charge. And so normally if we were to pour
  • 00:05:09
    oil into water it's going to separate. And the reason why is that fats are non polar.
  • 00:05:14
    They don't have a charge. But what's neat about phospholipids is that they have a head
  • 00:05:18
    that is going to have a negative charge and then they have the tails that are uncharged.
  • 00:05:23
    And so if you just throw a bunch of phospholipids in water they'll form these spheres, micelles,
  • 00:05:28
    or they'll form these spontaneous membranes. And so the cell membranes of all cells are
  • 00:05:34
    made up of phospholipids. And so bacteria, archaea, eukarya, plants, animals, fungi,
  • 00:05:40
    we all have cell membranes. And those membranes are made up of phospholipids. They regulate
  • 00:05:45
    what gets in and out a cell. Cholesterol is going to maintain the fluidity of the membrane.
  • 00:05:50
    And so this cell membrane right here is made up of phospholipids. Those phospholipids are
  • 00:05:54
    constantly moving back and forth and that's important because it allows things like oxygen
  • 00:05:59
    to get in and carbon dioxide to get out. But if the cell gets heated up those phospholipids
  • 00:06:04
    tend to fall apart. And if it get's really cold they'll crowd together and so the function
  • 00:06:09
    of cholesterol is to grab onto those fatty acid tails and hold them together when it
  • 00:06:14
    gets too cold but keep them apart . . . or hold them together when they get to warm and
  • 00:06:19
    keep them apart when they get too cold. And so cholesterol is important at maintaining
  • 00:06:23
    that integrity of the cell membrane. And you can see cholesterol in this diagram right
  • 00:06:27
    here. We can build it in each of our cells and we have to build it in our cells, but
  • 00:06:32
    we have to get a little bit of it in our diet. And so we need lipids in our diet. If we don't
  • 00:06:37
    have lipids we can't get energy and more importantly we can't make our cell membranes. However,
  • 00:06:42
    today everybody's getting the fat they need. This is my favorite place to eat when I go
  • 00:06:47
    to California because we don't have them in Montana. This is In-N-Out burger. I love the
  • 00:06:51
    taste of a big burger from In-N-Out. The lipids are great but there's probably too much trans
  • 00:06:57
    fats in there. It's not good for me and could lead to heart disease. But for now I'm going
  • 00:07:01
    to keep eating them. So that's lipids, that's fat and I hope that was helpful.
Etiquetas
  • lipids
  • fats
  • triglycerides
  • phospholipids
  • cholesterol
  • saturated fats
  • unsaturated fats
  • olestra
  • cell membranes
  • energy storage