How To Do Left Bundle Branch Pacing
Résumé
TLDRThis session on left bundle branch pacing features Dr. Paul Foley and Dr. Marek Jatreski discussing the technique's importance in cardiac pacing. They outline the physiological benefits of conduction system pacing over traditional methods, particularly in patients with bradycardia and heart failure. Dr. Foley emphasizes the need for precise lead placement to avoid complications, while Dr. Jatreski breaks down the procedure into four key steps: identifying the target area, lead insertion, monitoring lead depth, and confirming successful capture. The session highlights the challenges and future directions of this evolving technique in cardiac care.
A retenir
- 🎤 Introduction to left bundle branch pacing
- 🩺 Importance of conduction system pacing
- 📈 Indications for pacing: bradycardia, heart failure
- 🔍 Steps in left bundle branch pacing
- ⚙️ Challenges in the procedure
- 📊 Confirming successful capture
- 💡 Physiological pacing benefits
- ⚠️ Risks of overscrewing
- 🧬 Impact of scar tissue on pacing
- 🔮 Future of conduction system pacing
Chronologie
- 00:00:00 - 00:05:00
In this session, experts discuss left bundle branch pacing, highlighting its importance in treating patients with bradycardia, heart failure, and defibrillator needs. Dr. Paul Foley introduces conduction system pacing, emphasizing its role in minimizing right ventricular pacing, which can lead to cardiomyopathy. He outlines the physiological pacing's potential benefits, including improved outcomes in heart failure patients and reduced hospitalization rates.
- 00:05:00 - 00:10:00
Dr. Foley elaborates on the challenges of right ventricular pacing, noting that a significant percentage of patients require upgrades to biventricular pacing. He discusses the importance of understanding the pacing system's anatomy and the need for precise device selection to avoid complications. The session emphasizes the need for thorough follow-up and monitoring to ensure effective pacing and patient safety.
- 00:10:00 - 00:15:00
The discussion transitions to the technical aspects of left bundle branch pacing, with Dr. Marek Jatreski sharing his experience. He outlines a four-step approach to the procedure: identifying the target area, lead insertion techniques, monitoring lead depth, and confirming successful capture of the left bundle branch. He emphasizes the importance of anatomical landmarks and ECG analysis during the procedure.
- 00:15:00 - 00:20:00
Dr. Jatreski explains the significance of the target area near the His bundle and the use of fluoroscopy and ECG to guide lead placement. He discusses the tools available for the procedure, including the sheath and delivery catheter, and the importance of understanding the lead's response during insertion to ensure proper placement.
- 00:20:00 - 00:25:00
The session highlights the need for careful monitoring of lead insertion to prevent overscrewing and potential complications. Dr. Jatreski introduces the concept of 'screw beads' as indicators of successful lead placement, emphasizing their presence in successful cases and their absence in unsuccessful attempts.
- 00:25:00 - 00:30:00
Dr. Jatreski discusses the challenges posed by scar tissue in the septum, which can hinder lead advancement. He shares insights on how to navigate these challenges and the importance of recognizing the difference between myocardial and conduction system capture during the procedure.
- 00:30:00 - 00:35:00
The conversation shifts to the confirmation of left bundle branch capture, with Dr. Jatreski explaining the differential output maneuver and the use of programmed stimulation to verify successful pacing. He emphasizes the need for a thorough understanding of the pacing system's physiology to achieve optimal results.
- 00:35:00 - 00:41:00
The session concludes with a discussion on the future of conduction system pacing, with both experts expressing optimism about its potential benefits over traditional pacing methods. They highlight the importance of ongoing research and clinical trials to further validate these techniques and improve patient outcomes.
Carte mentale
Vidéo Q&R
What is left bundle branch pacing?
Left bundle branch pacing is a technique used to stimulate the left bundle branch of the heart's conduction system to improve cardiac function.
What are the indications for conduction system pacing?
Indications include bradycardia, heart failure requiring resynchronization, and patients needing defibrillators.
What are the main steps in left bundle branch pacing?
The main steps are identifying the target area, lead insertion, monitoring lead depth, and confirming capture.
What challenges are associated with left bundle branch pacing?
Challenges include longer procedure times, the need for specialized equipment, and ensuring correct lead placement.
How do you confirm successful capture in left bundle branch pacing?
Successful capture is confirmed through ECG changes and programmed stimulation techniques.
What is the significance of physiological pacing?
Physiological pacing aims to minimize pacing-induced cardiomyopathy and improve cardiac function.
What is the role of the his bundle in pacing?
The his bundle is a key structure in the conduction system that can be targeted for pacing to improve heart function.
What are the risks of overscrewing during lead placement?
Overscrewing can lead to perforation of the heart wall, which is a serious complication.
How does scar tissue affect pacing?
Scar tissue can hinder lead progression and affect the quality of pacing, potentially leading to suboptimal outcomes.
What is the future of conduction system pacing?
The future includes advancements in technology and techniques to improve the efficacy and safety of pacing.
Voir plus de résumés vidéo
- 00:00:00[Music]
- 00:00:08i'd like to welcome you all to
- 00:00:11this session on how to do left bundle
- 00:00:14branch pacing it is a pleasure for me to
- 00:00:17welcome
- 00:00:18dr paul foley who is very experienced
- 00:00:21in planter in both crt and imagine
- 00:00:25conducting tissue pacing
- 00:00:29we also have dr marek and
- 00:00:32jatreski who will talk to us about his
- 00:00:36experience
- 00:00:37with handling leads and using catheters
- 00:00:41and really the nitty gritty as to how to
- 00:00:44perform
- 00:00:46left bundle branch area pacing
- 00:00:50so i would like to welcome paul to
- 00:00:54give us an overview of conducting
- 00:00:56conduction system
- 00:00:58pacing thank you thank you paco
- 00:01:01and uh it's great honor to give this
- 00:01:04talk and thank you for the welcome
- 00:01:06so i'm talking about perspectives on
- 00:01:07conduction system pacing
- 00:01:09by which obviously we refer to his
- 00:01:11bundle and left conducting
- 00:01:13system pacing and
- 00:01:16there are obviously three main
- 00:01:17indications for pacing
- 00:01:19bradycardia those patients with heart
- 00:01:22failure who need cardiac
- 00:01:23resynchronization devices
- 00:01:25and patients who need defibrillators and
- 00:01:28often those
- 00:01:29indications uh more than one indication
- 00:01:32is present in
- 00:01:33the patients so where does physiological
- 00:01:36pacing come in
- 00:01:37the first major indication where it
- 00:01:40could be considered is atrial
- 00:01:41ventricular block
- 00:01:42and patients with very pronounced
- 00:01:44first-degree av
- 00:01:45block may experience right ventricular
- 00:01:48pacing
- 00:01:48even in the face of algorithms designed
- 00:01:51to minimize it because davy block is so
- 00:01:54prolonged in patients with two to one
- 00:01:57and complete av block or those patients
- 00:01:59who've had navy node ablation
- 00:02:01these patients expect to have very high
- 00:02:03burden of right ventricular pacing
- 00:02:05and we know that can be associated with
- 00:02:07patiently induced cardiomyopathy
- 00:02:10there's also a group of patients who've
- 00:02:11had left ventricular leads implanted
- 00:02:13and these uh for whatever reason aren't
- 00:02:15working so that may be because they
- 00:02:17can't get their
- 00:02:18anatomical constraints and maybe the
- 00:02:20threshold is high
- 00:02:22or another problem is obviously phrenic
- 00:02:24nerve pacing
- 00:02:25and so in this situation physiological
- 00:02:27pacing can
- 00:02:29serve as sort of bailout strategy and
- 00:02:32lastly
- 00:02:34left ventricular and right ventricle
- 00:02:35pacing is well established in randomized
- 00:02:37clinical trials but there are a number
- 00:02:38of studies
- 00:02:39comparing biventure pacing with
- 00:02:42physiological pacing
- 00:02:43suggesting similar outcomes in terms of
- 00:02:46left ventricular remodeling
- 00:02:47or possibly better remodeling and a
- 00:02:50narrow qrs
- 00:02:51and this is an area of uh active study
- 00:02:53but still
- 00:02:54present the major guidelines would
- 00:02:57suggest for patients heart failure in
- 00:02:59that bundle
- 00:03:00these patients should have crt
- 00:03:04so is right ventricular pacing a problem
- 00:03:06well we talked about
- 00:03:07uh pacing-induced cardiomyopathy which
- 00:03:09occurs in approximately 20
- 00:03:11of patients and this is a very nice
- 00:03:13study from cougars group
- 00:03:14united states where one hospital
- 00:03:16undertook normal
- 00:03:18right ventricular apron based pacing and
- 00:03:20the other hospital undertook his bundle
- 00:03:22of pacing
- 00:03:23and what they saw was a reduction the
- 00:03:26primary endpoint of heart
- 00:03:27death heart failure hospitalization or
- 00:03:30upgrading to bio-ventricular pacing
- 00:03:32by around 30 and in fact if you look to
- 00:03:35those patients receiving over 40
- 00:03:37right ventricular apical pacing there
- 00:03:39was a significant reduction
- 00:03:41in the risk of heart failure
- 00:03:42hospitalization which was even present
- 00:03:45if you look to those patients receiving
- 00:03:47only 20 percent now obviously for
- 00:03:49patients there are
- 00:03:50options in terms of instead of right
- 00:03:53ventricular equal pacing it will
- 00:03:54lead so there's lead list pacing and
- 00:03:56cardiac resynchronization
- 00:03:58pacing and the other question
- 00:04:01arises is how much a problem is how
- 00:04:04often do upgrades occur
- 00:04:06and if we look at the esc survey from
- 00:04:082019
- 00:04:09about 30 percent of the patients
- 00:04:11undergoing crt were actually upgrades
- 00:04:13from pre-existing
- 00:04:14right ventricular april based system and
- 00:04:17there's obviously a procedure timer says
- 00:04:18that around 90 minutes
- 00:04:20approximately six percent of patients
- 00:04:22had complications and the pace qrs
- 00:04:24is actually reasonably broad at 137
- 00:04:27milliseconds
- 00:04:28so it may be but implanting a
- 00:04:30physiological base
- 00:04:31pacing system from the start would
- 00:04:33reduce the risk of the patient needing
- 00:04:35an upgrade to 500 pesos
- 00:04:37now this sounds very attractive but
- 00:04:39there are challenges
- 00:04:40we know the procedure time tends to be
- 00:04:42long with physiological based
- 00:04:44pacing you need a certain level of
- 00:04:46implant equipment
- 00:04:47often ep systems although a patient
- 00:04:51patient analyzer can be used there's
- 00:04:54the level of knowledge based on so need
- 00:04:57to understand the signals that are
- 00:04:58coming back
- 00:04:59and particularly that's important uh
- 00:05:01when the patient's being followed up
- 00:05:03it's very important to select the
- 00:05:04correct device so if you look at his
- 00:05:06bundle pacing the
- 00:05:07history may be implanted into the atrial
- 00:05:09port the right ventricular port
- 00:05:11or the left ventricular port and so the
- 00:05:14device
- 00:05:15you select will be important
- 00:05:17particularly because you need to avoid
- 00:05:19ventricular safety pasting for his
- 00:05:21bundle systems
- 00:05:23his bundle pacing itself is associated
- 00:05:25with slightly higher thresholds
- 00:05:26and that can have implications of the
- 00:05:28battery life the r waves tend to be
- 00:05:30lower typically around two millivolts
- 00:05:32there's always a question about will the
- 00:05:34hv block distal to where the lead is
- 00:05:37implanted occur
- 00:05:38later on you need to be absolutely
- 00:05:40certain the patient's getting his
- 00:05:41capture
- 00:05:42and it's not sexual pacing and a
- 00:05:44follow-up
- 00:05:45there are changes in in the follow-up
- 00:05:48pattern so remote follow-up
- 00:05:50isn't really an option for these
- 00:05:52patients and that's uh obviously an
- 00:05:53important consideration
- 00:05:54moment during covert uh auto capture
- 00:05:58does not work and as we said ventricular
- 00:06:00safety pacing
- 00:06:02for his fundamental systems isn't
- 00:06:03applicable and the numbers of patients
- 00:06:06involved in the trials about uh 1438
- 00:06:10published cases
- 00:06:11largest series of 304 but no major
- 00:06:14randomized clinical trials
- 00:06:16left bundle branch pacing which america
- 00:06:18is going to talk about shortly
- 00:06:20uh again it's very important to get the
- 00:06:22correct position
- 00:06:23it's slightly more attractive in terms
- 00:06:24of thresholds tend to be
- 00:06:26a lot lower so analogous to right
- 00:06:28ventricular april pacing
- 00:06:30and the r wave sensing is normal our way
- 00:06:34but there is the attendant risk of
- 00:06:36perforation and the numbers of patients
- 00:06:38implanted in in the
- 00:06:40case reports and case series is around
- 00:06:41530 of the largest series
- 00:06:44being so far 100 and again no randomised
- 00:06:46clinical trials
- 00:06:48in this area
- 00:06:51now we talked about the looking at
- 00:06:54signals
- 00:06:55there is a level of precision uh which
- 00:06:58is required for physiological pacing
- 00:07:00which is beyond that
- 00:07:02the right ventricular april based pacing
- 00:07:04so this
- 00:07:05the first schematic on the left you see
- 00:07:07the outputs on the y axis
- 00:07:09and the four different positions where
- 00:07:12there are multiple different thresholds
- 00:07:13that can be obtained and that's
- 00:07:15important during follow-up to be aware
- 00:07:17of what you're
- 00:07:19what you're seeing and also at the time
- 00:07:20of implantation
- 00:07:22america has done some very impressive
- 00:07:24work
- 00:07:25on looking at program stimulation to
- 00:07:27confirm that you're in the his bundle
- 00:07:30rather than the myocardium so there's
- 00:07:32the fatigue ability when the hispanic
- 00:07:34stimulated and not seen when the mark
- 00:07:36harden is stimulated
- 00:07:37extra stimuli and there are various
- 00:07:39morphological features
- 00:07:41which again it's very important to be
- 00:07:42sure that the
- 00:07:45the lead is in the correct position
- 00:07:46because actually it can be quite hard to
- 00:07:48differentiate between
- 00:07:49non-selective hispanic capture and
- 00:07:51myocardial capture
- 00:07:53so you're looking for a very steep um
- 00:07:56peak for non-selective capture rather
- 00:07:59than a slight plateau and myocardial
- 00:08:01catcher
- 00:08:02the absence of a notch in v1 in the
- 00:08:05s wave and also the qrs duration should
- 00:08:08be narrow
- 00:08:11so moving on to uh left
- 00:08:14um conducting system pacing which
- 00:08:16america is going to talk about
- 00:08:18again the same position is required so
- 00:08:20uh
- 00:08:21this is a lead so the lead in these
- 00:08:24schematics one is in the left conductive
- 00:08:26system the other is
- 00:08:27left ventricular septum and you can see
- 00:08:29the qrs morphology
- 00:08:30is very similar and the qrs duration
- 00:08:34is the same but when high fidelity
- 00:08:37mapping is undertaken
- 00:08:39in the patients where the non-selective
- 00:08:41left conducting system is stimulated
- 00:08:44the pukenji activation is prior to the
- 00:08:46qrs
- 00:08:47and that's shown the red arrows whereas
- 00:08:49when is the
- 00:08:50leaders in the left ventricular septum
- 00:08:52stimulating left conducting system
- 00:08:54the kinji fibers are within the qrs
- 00:08:57onset
- 00:08:58and the left ventricular activation time
- 00:08:59is shorter if you're
- 00:09:01in the left conducting system rather
- 00:09:03than the left ventricular septum
- 00:09:05and this is just to say that there is a
- 00:09:07level of complexity
- 00:09:09to physiological pacing which is greater
- 00:09:12than that with standard right
- 00:09:14pacing so thank you very much
- 00:09:19thank you paul that's a very nice
- 00:09:20overview this is clearly very exciting
- 00:09:23from the
- 00:09:24scientific point of view it's very early
- 00:09:26days
- 00:09:27but it is really very encouraging and
- 00:09:30opens up
- 00:09:31a whole lot of new questions i think as
- 00:09:33well i think from the clinical point of
- 00:09:36view
- 00:09:36um there is a great excitement as to
- 00:09:40whether this is superior to right
- 00:09:42ventricular pacing i agree with you that
- 00:09:45there is some data out there to show
- 00:09:47that right ventricular pacing is
- 00:09:48detrimental
- 00:09:50um but i i do wonder whether this is
- 00:09:53due to an underlying cardiomyopathy
- 00:09:57i think that if you look at right
- 00:09:59ventricular pacing in a completely
- 00:10:01healthy ventricle i don't i can't see
- 00:10:04anything from the literature to
- 00:10:06confidently say that right ventricular
- 00:10:08pacing is detrimental
- 00:10:11but yes of course we all see patients
- 00:10:13who
- 00:10:14have a right ventricular pacing induced
- 00:10:16cardiomyopathy
- 00:10:19i think obviously this is something that
- 00:10:22i'm sure marek will will
- 00:10:23will cover um there are
- 00:10:27slight worries about the fact that we
- 00:10:30are dealing with
- 00:10:31imperfect technology and in mature
- 00:10:33technology at the moment
- 00:10:35and there's clearly a need to work on
- 00:10:38both
- 00:10:39the devices and the leads and
- 00:10:42in my experience also the
- 00:10:46catheters the guiding catheters and the
- 00:10:49wires and various other things so
- 00:10:51without um
- 00:10:54and discussing anymore i'd like to
- 00:10:57welcome professor marek
- 00:10:58and jackie who will take us through
- 00:11:01left bundle branch pacing thank you
- 00:11:04marek
- 00:11:05hello everybody thank you for the
- 00:11:09kind invitation my task
- 00:11:12is to tell you in a few words how to do
- 00:11:15left bundle branch pacing
- 00:11:18this is a very new tech technique
- 00:11:21and i do not claim that i have all the
- 00:11:23answers and i know how to do it
- 00:11:25best every operator have a slightly
- 00:11:28different
- 00:11:28approach sometimes quite different
- 00:11:30approach and i'm not claiming mine is
- 00:11:33the best
- 00:11:34but this is i will just share with you
- 00:11:36the experience that i have
- 00:11:38the first left bundle branch pacemaker i
- 00:11:41implanted was
- 00:11:42always almost two years ago since that
- 00:11:44time in my lab we have implanted over
- 00:11:46300
- 00:11:47such devices so that gives me certain
- 00:11:50room
- 00:11:53where i can move the experience they
- 00:11:55have that i can share with you
- 00:11:58and because of the time frame i have
- 00:12:00decided to
- 00:12:01break down this complex procedure into
- 00:12:04four simple steps
- 00:12:06so okay these are my
- 00:12:10moderate disclosures and let's move to
- 00:12:14the
- 00:12:14to these four steps so i think the whole
- 00:12:18procedure
- 00:12:19rests on four pillars first you need to
- 00:12:22identify the target area
- 00:12:24on the mid sector you need to
- 00:12:27know how to get there and where it is
- 00:12:30then you need to
- 00:12:31learn how to screw the lead it is very
- 00:12:34important it's not a simple task like
- 00:12:36you have with active fixation lead where
- 00:12:38you just
- 00:12:39do a few rotations and and that's it
- 00:12:42you need to know how to interpret
- 00:12:44responses to lead rotation
- 00:12:46because that's crucial to success we'll
- 00:12:49talk about that
- 00:12:50then you need to monitor delete depth
- 00:12:52during screwing
- 00:12:53to prevent over screwing because if you
- 00:12:56go
- 00:12:56too deep you'll end in the left
- 00:12:58ventricle that's something we don't want
- 00:13:00to
- 00:13:01so that's again a very important
- 00:13:04step of the procedure and then the final
- 00:13:07step
- 00:13:08that been very important for me from the
- 00:13:11scientific point of view because we
- 00:13:13publish a lot about that is to how to
- 00:13:15confirm
- 00:13:16that the acute endpoint of the procedure
- 00:13:19was actually achieved
- 00:13:20how to confirm like battle branch
- 00:13:22capture because it's not like
- 00:13:24just rv procedure you implant you have a
- 00:13:26captcha and that's it
- 00:13:28no you need to confirm that you capture
- 00:13:30the structure
- 00:13:31that you are interested in this
- 00:13:33conduction system
- 00:13:35okay so let's go to the step one
- 00:13:39uh the target area where it is so the
- 00:13:42target area
- 00:13:42is on the septum and it's
- 00:13:46close to the his bundle area marked with
- 00:13:48the red
- 00:13:49dot it's close to the tricuspid
- 00:13:52annulus marked with this yellow line
- 00:13:57it's pretty vast area actually the area
- 00:13:59that i marked is
- 00:14:01perhaps bigger than most operators would
- 00:14:03agree
- 00:14:04the best part is close to the his one
- 00:14:06two centimeters from the historic the
- 00:14:08proximal
- 00:14:09bundle but sometimes it is more
- 00:14:11difficult to get that than to the other
- 00:14:13parts of the arborization of left bundle
- 00:14:15and i do not hesitate to use those areas
- 00:14:18so very often we go slightly more
- 00:14:20optical and slightly more inferior to
- 00:14:22get the left bundle
- 00:14:24and the cures obtained from from those
- 00:14:27areas are also excellent so how do you
- 00:14:30know on the floor where that area is
- 00:14:33well you can use the the contrast as you
- 00:14:35see in this picture in the middle of
- 00:14:37this slide
- 00:14:38but i use that very very rarely actually
- 00:14:41a good implant and knows where the
- 00:14:42tricaster drink is
- 00:14:44judging by the movement of the sheep
- 00:14:47looking at the endocrine
- 00:14:49potential the potential and the hl
- 00:14:50potential
- 00:14:52and sometimes you see the his potential
- 00:14:54so you also know where is the
- 00:14:55upper part of the tricaster ring and
- 00:14:57that's enough you don't need to use the
- 00:14:59contrast
- 00:15:00you most of the time you don't need to
- 00:15:02even identify the his
- 00:15:03to know what the left bundle branch area
- 00:15:05is just
- 00:15:06the tricuspid ring is the perfect
- 00:15:09anatomical marker
- 00:15:10how to get there we do not have
- 00:15:12dedicated tools
- 00:15:13uh as you have heard a moment ago but we
- 00:15:17still have our tools that are not that
- 00:15:18bad we use the
- 00:15:19sheath the heat sheath from the select
- 00:15:22secure family from medtronic
- 00:15:24which is designed for his but it also
- 00:15:26directs you very well
- 00:15:28on the septum because of this second
- 00:15:30septal curve
- 00:15:32and that's enough to get the left bundle
- 00:15:34in majority of cases
- 00:15:36sometimes when there is unfavorable
- 00:15:38anatomy
- 00:15:39the rotation of the heart that somehow
- 00:15:41makes this shift not very useful
- 00:15:44i use the s10 delivery catheter
- 00:15:47which allows us to target the slightly
- 00:15:50more inferior septum on the septum that
- 00:15:53is slightly
- 00:15:54more rotated than usually but we
- 00:15:56definitely need
- 00:15:58a different shape my ideal sheath would
- 00:16:00be
- 00:16:01i would have slightly bigger diameter
- 00:16:04inside in
- 00:16:05bigger lumen would be more sturdy
- 00:16:08because the
- 00:16:08the obstacle to implantation is is the
- 00:16:11kinking
- 00:16:11and if you have to rotate the sheath
- 00:16:14very strongly
- 00:16:15it prevents the leak freely moving
- 00:16:17inside and that's the
- 00:16:18biggest obstacle to implant the
- 00:16:22the lead in difficult anatomies the
- 00:16:25second
- 00:16:25marker and you uh the second tool that
- 00:16:28you use to define your target area
- 00:16:31is the ecg that you see on the right
- 00:16:33part of the slide
- 00:16:35and when you choose your target area
- 00:16:38judging by a floor or image then you do
- 00:16:41the
- 00:16:42initial pace mapping and you obs you you
- 00:16:45analyze the based qrs and this based qrs
- 00:16:48should be compatible with the
- 00:16:50mid central area that is the polarity of
- 00:16:53the qrs in lead
- 00:16:552 and lead 3 should be discarded
- 00:16:58leak 2 should be always positive while
- 00:17:00lead 3 should always have some negative
- 00:17:03component
- 00:17:04i'm not saying it should be completely
- 00:17:05negative like in this example
- 00:17:07but it should have a negative component
- 00:17:09and that's a perfect position
- 00:17:11if you pay attention to lead v1 you will
- 00:17:14see this famous
- 00:17:16notch at the nadio and that's a good
- 00:17:18thing to have
- 00:17:19but it's not obligatory another thing
- 00:17:22that you sometimes observe
- 00:17:23is that the qrs like you can appreciate
- 00:17:26indeed before
- 00:17:27v5 is already quite nice it's slightly
- 00:17:30more narrow than in other
- 00:17:32areas i don't know why is that
- 00:17:35maybe this is some distant capture of
- 00:17:37the left bundle already or maybe this is
- 00:17:39some kind of non-selective
- 00:17:40sculpture but this us is nicer and
- 00:17:43that's the perfect spot
- 00:17:45to screw the lead inside the septum if
- 00:17:48you have this floor
- 00:17:49this ecg you just go to the
- 00:17:52next step and this next step
- 00:17:55is to rotate the delete
- 00:17:59and uh here i have to go to one of the
- 00:18:02studies that we published on left valley
- 00:18:04branch pacing and that
- 00:18:06study came out of our need two years ago
- 00:18:08when he
- 00:18:09when we did start this procedure i was
- 00:18:11puzzled why sometimes it is so easy
- 00:18:14to achieve left panel branch facing just
- 00:18:16a few rotations
- 00:18:17and it's done and sometimes you fight
- 00:18:20and fight and have problems
- 00:18:23sometimes delete will not progress you
- 00:18:25you you
- 00:18:26rotate the lead you see the torque build
- 00:18:28up in the lead as you see in the
- 00:18:30inferior right part of the slide the
- 00:18:33lead is
- 00:18:34completely is is
- 00:18:37the torque is there you see the force of
- 00:18:39your rotations there and they do not
- 00:18:41transmit to the heart
- 00:18:42why is that and sometimes there the
- 00:18:46torque the attention
- 00:18:47immediately transmitted severely hard so
- 00:18:49we did this cadaver model
- 00:18:51in this model we used freshly heart from
- 00:18:55freshly diseased people
- 00:18:56suicide victims characters and victims
- 00:19:00we use the same lead the 3830 model
- 00:19:03and we use the same delivery sheath and
- 00:19:05the same
- 00:19:06operator was handling ensuring that the
- 00:19:10pressure the the support was more or
- 00:19:12less the same as doing real life
- 00:19:14procedure
- 00:19:15and we observed three types of responses
- 00:19:18two types of effects
- 00:19:19and actually they resemble very very
- 00:19:22much what we did observe during real
- 00:19:24life procedures
- 00:19:25so the first response effect was the
- 00:19:29thing we call entanglement effect you
- 00:19:32can't progress because the endocardium
- 00:19:35wraps around the helix around the lead
- 00:19:38and prevents progression of the lead
- 00:19:41inside the septum your if you have a
- 00:19:44such response
- 00:19:45that your torque does not transmit my
- 00:19:48advice is not to find with that position
- 00:19:50you have to find another position
- 00:19:52that was a very common response of set
- 00:19:55on on the cadaver model
- 00:19:56but it's also observed in real life the
- 00:19:59second response is
- 00:20:01you rotate the lead you see the torque
- 00:20:04build up and it's released
- 00:20:05so it goes inside of the heart but it's
- 00:20:08not changing the cures
- 00:20:09on fluoro you see no lead movement and
- 00:20:12most likely you have a drill response
- 00:20:15drill effect you are just moving in the
- 00:20:17same position and drilling a hole in the
- 00:20:19septum this is a bad thing
- 00:20:21because firstly you will not get to the
- 00:20:23left bundle and secondly
- 00:20:24the lead and the myocardium are very
- 00:20:27loosely connected and
- 00:20:28it might dislodge later on the the
- 00:20:31response the effect that we look for is
- 00:20:33the screwdriver effect you rotate and
- 00:20:35each rotation
- 00:20:36after initial torque buildup is
- 00:20:38transmitted to the heart
- 00:20:40and actually results in a deeper and
- 00:20:42deeper position of delete that's the
- 00:20:44the kind of response that we want but at
- 00:20:47the same time this is the kind of
- 00:20:48response that is also
- 00:20:50risky because you can
- 00:20:53open screw you can end in left ventricle
- 00:20:55so that
- 00:20:57makes us go once you understand these
- 00:20:59responses
- 00:21:00you need to differentiate actually
- 00:21:02between the screwdriver and the drill
- 00:21:04because both behave the same in your
- 00:21:06hands both
- 00:21:07result in the transmission of the torque
- 00:21:10the difference you can observe
- 00:21:12and differentiate between these the
- 00:21:14difference you can differentiate these
- 00:21:16two by looking at the
- 00:21:17ecg and plural and this is what we will
- 00:21:20discuss in the next slide
- 00:21:24so how to differentiate between these
- 00:21:26two responses and how to ensure
- 00:21:29that you do not end as this
- 00:21:32one of these two leads that you see on
- 00:21:33our cadillac model that went so smoothly
- 00:21:35to deception
- 00:21:36that it ended in the left ventricle how
- 00:21:38to stop at the sub-endocardial layer
- 00:21:41close to the left ventricle but not into
- 00:21:43that ventricle
- 00:21:44and the the the the the mainstream
- 00:21:48technique
- 00:21:49is space mapping the pace mapping the
- 00:21:52perfect thing would be to have constant
- 00:21:54face mapping while scrolling
- 00:21:55uh for this we need some kind of
- 00:21:57revolving adapter that you could connect
- 00:22:00the external pacemaker with the digital
- 00:22:02pin of delete unfortunately we
- 00:22:03did the manufacturers the industry still
- 00:22:06does not produce a thing like that
- 00:22:08i have modified several shock alligator
- 00:22:12clips to produce a kind of revolving
- 00:22:14tool and that would enable
- 00:22:18a continuous face mapping while the
- 00:22:20elite progresses inside the septum but
- 00:22:22they are all far from being perfect
- 00:22:25so i rely mainly on interrupted pacing
- 00:22:28but here this ecg was taken from a
- 00:22:31patient where continuous pacing was done
- 00:22:34while the lead progresses and it is very
- 00:22:37very important to be familiar with the
- 00:22:39change of the paste cures patterns you
- 00:22:42start with this pattern on the
- 00:22:44left where you see broad qrs notched qrs
- 00:22:48and in v1 you can appreciate in this red
- 00:22:50circle that trees are not at the medium
- 00:22:54when you get deeper the cure should
- 00:22:58change and that's the difference between
- 00:22:59the
- 00:23:00screwdriver effect and the drill
- 00:23:03response
- 00:23:04because in the drill response the qrs
- 00:23:06will not change here it changes
- 00:23:08and you see that the the notch in v1
- 00:23:10disappears
- 00:23:11the keywords becomes slightly more
- 00:23:13spanky slightly more smooth
- 00:23:16you add one or two more rotations and
- 00:23:18then you see that the curious is
- 00:23:20very spiky and at the end of the qrs and
- 00:23:23v1 slide
- 00:23:24r prime appears if you add
- 00:23:27still few more rotations you will
- 00:23:29observe that the
- 00:23:30big r at the end of the qrs is present
- 00:23:34and you have
- 00:23:35full blown right bundle branch block
- 00:23:37pattern in b1
- 00:23:38and that's the keywords that you like
- 00:23:40and this is the moment you stop
- 00:23:42once you have a qrs that is compatible
- 00:23:45with left bundle branch capture that is
- 00:23:46nice
- 00:23:47it's smooth it's narrow that's the way
- 00:23:51uh to know that you should stop and that
- 00:23:53still is the mainstay technique to
- 00:23:56to prevent overscrewing you either do it
- 00:23:58continuously or more
- 00:23:59commonly in an interrupted fashion after
- 00:24:02a few
- 00:24:03rotations you check the qrs you add more
- 00:24:05rotation
- 00:24:06or not that's the best thing uh
- 00:24:09that we have and some people will tell
- 00:24:12you that the
- 00:24:13monitoring impedance is important i
- 00:24:15never did that 300 cases
- 00:24:17no monitoring of impedance and it works
- 00:24:19so i don't think that's really necessary
- 00:24:21based keywords morphology is the best
- 00:24:24however
- 00:24:25right now i rely a little bit more on
- 00:24:27the thing that you see here i call
- 00:24:29and this screw bits of when you
- 00:24:33go with the lead deep inside the septum
- 00:24:35you irritate the tissues
- 00:24:37and this irritation causes premature
- 00:24:39complexes
- 00:24:41and if you look at them for example this
- 00:24:43is a classical example
- 00:24:44of a shower of premature beasts from the
- 00:24:47septum
- 00:24:47you will see that in this patient with
- 00:24:49left bundle branch qrs
- 00:24:52suddenly a curious appears with r
- 00:24:55at the end of the keywords in d1 these
- 00:24:57are gross and in the middle you see
- 00:25:00a cure that is completely right bundle
- 00:25:02branch
- 00:25:03morphology which is exactly
- 00:25:07the indication that you want to have
- 00:25:10that your lead tip the helix is
- 00:25:13irritating
- 00:25:14the sub-endocardial layer on the left
- 00:25:16side and that's the
- 00:25:18perfect indication that you should stop
- 00:25:20tearing
- 00:25:21that's the only actually tool that i
- 00:25:23very of use right now
- 00:25:25you do rotations you observe you look
- 00:25:27for screw bits if you have them
- 00:25:29you don't need to have anything more
- 00:25:31because if when you start face mapping
- 00:25:34at that moment you will have a curious
- 00:25:35morphology which will be identical to
- 00:25:37your last screw bit
- 00:25:39and that's the information that if you
- 00:25:42don't have them
- 00:25:43you need to add more screws if you have
- 00:25:45them you need to stop to prevent over
- 00:25:47screwing to
- 00:25:47you to prevent perforation
- 00:25:51so the screw bits are the way to go for
- 00:25:52me right now and interrupted
- 00:25:54or continuous phase mapping is another
- 00:25:58way to prevent um overscrewing
- 00:26:02and of course you have other tools
- 00:26:05the plural and the and the kind of
- 00:26:07signal from the pacing leak
- 00:26:09to prevent um going too deep
- 00:26:13especially lao is very very useful on
- 00:26:16lao you directly see the progression of
- 00:26:19the lead and if you are not sure
- 00:26:21if you have a screwdriver response or
- 00:26:24drill response from your lead lao
- 00:26:28will tell you the truth because in the
- 00:26:30drill response there is no
- 00:26:31movement of delete to the left while in
- 00:26:34the screwdriver
- 00:26:35each rotation will move slightly delete
- 00:26:38deep to the left
- 00:26:39so leo is 30 is obligatory during
- 00:26:43implantation especially in difficult
- 00:26:44cases when you do not get the
- 00:26:46bundle during your first attempt
- 00:26:49another thing is to look for the left
- 00:26:51bundle uh potential on delete because if
- 00:26:53it's there
- 00:26:54it's again a proof that you are in this
- 00:26:57sub-endocardial layer because that's the
- 00:26:58only
- 00:26:59area where you can record it so you when
- 00:27:01you have left bundle potential of
- 00:27:03archangel potential
- 00:27:04that's again an indicator to stop
- 00:27:07absolutely stop
- 00:27:08uh screwing because if you do not if you
- 00:27:10will go
- 00:27:11to look for a nicer potential your
- 00:27:14chances of perforation are skyrocketing
- 00:27:17uh when it comes to left bundle branch
- 00:27:19potential it is very important
- 00:27:20to recognize it not only when it's nice
- 00:27:24big and almost like his potential but
- 00:27:26also recognize it when it's small
- 00:27:28like here on the far right
- 00:27:31when you see a potential that is not
- 00:27:34much bigger than the artifact level
- 00:27:36it's already a good sign and you need
- 00:27:39a clean signal for this very often the
- 00:27:41potential even
- 00:27:42when it's big is completely buried with
- 00:27:45the v
- 00:27:46in the v potential as you see in the
- 00:27:47middle example
- 00:27:49uh this is because there's a kind of
- 00:27:51injury and the kind of injury
- 00:27:53somehow merges the left bundle potential
- 00:27:55and the
- 00:27:56ventricular potential into one complex
- 00:27:58you need to
- 00:27:59be able to see the potential inside you
- 00:28:03see
- 00:28:03similar situation on the on the left
- 00:28:05where the
- 00:28:06potential is moderate but again linked
- 00:28:09with db potential by the kind of injury
- 00:28:11and the trick to see that is to
- 00:28:15measure the potential
- 00:28:18to qrs to see that this is not a curious
- 00:28:21it starts much
- 00:28:22before the cures you know this is a
- 00:28:23potential
- 00:28:25okay so when you other
- 00:28:30you need to finalize the procedure with
- 00:28:33the
- 00:28:34fourth step the step to confirm that you
- 00:28:37have left bundle branch capture
- 00:28:39the mainstay technique for this known
- 00:28:41from the his bundle
- 00:28:43uh arena was the differential output
- 00:28:45maneuver just
- 00:28:46go down with the output of up with the
- 00:28:48output i want to observe the change in
- 00:28:50curves morphology
- 00:28:51this is based on very simple premise
- 00:28:54that there is a difference
- 00:28:55in captured threshold between the
- 00:28:57myocardium and the conduction system
- 00:28:59and yes you can use that technique in my
- 00:29:01experience this technique works
- 00:29:03only in 22 of the cases in all other
- 00:29:06cases the thresholds are equal
- 00:29:09when it works it looks like that the qrs
- 00:29:12on the right of this example on the
- 00:29:14right you see
- 00:29:15non-selective qrs that transitions into
- 00:29:17selected cures in d1 there is an obvious
- 00:29:20change from
- 00:29:21small r sometimes almost absent r to
- 00:29:24full blown right bundle branch block
- 00:29:26pattern
- 00:29:26on the left you see myocardial response
- 00:29:29when the non-selected qrs transitions
- 00:29:31into broader qrs
- 00:29:33that still has in v1 kind of right
- 00:29:36bundle branch morphology
- 00:29:37but it's much broader sometimes not and
- 00:29:39this is loss
- 00:29:41of conduction system capture and you
- 00:29:43have only myocardial
- 00:29:44capture even if you have this response
- 00:29:48during the procedure it will not be
- 00:29:49there
- 00:29:50next day the thresholds will be almost
- 00:29:52all almost
- 00:29:53always equal and this is why you need a
- 00:29:55different technique to confirm
- 00:29:57that you have reached your endpoint the
- 00:30:01the capture of the left bundle and for
- 00:30:03this we
- 00:30:04are using in every case programmed deep
- 00:30:07septal stimulation the technique that we
- 00:30:09developed last year and published it
- 00:30:11in the jc is
- 00:30:15in my opinion necessary in vast majority
- 00:30:18of cases
- 00:30:20it's also based on very simple uh
- 00:30:23uh premise that there's a difference in
- 00:30:26in refractoriness between myocardial
- 00:30:29tissue and
- 00:30:30conducting conducting system in between
- 00:30:32left bundle and the adjacent myocardium
- 00:30:35and even if there are no differences or
- 00:30:37the differences are small
- 00:30:38you can produce the differences by using
- 00:30:40different pacing techniques
- 00:30:42here you see in the lower example uh
- 00:30:46classic drive 600 milliseconds drive
- 00:30:49and then a premature um that you will
- 00:30:53find the left bundle refractory and
- 00:30:57myocardium responsive and you will see a
- 00:31:00change in qs morphology from
- 00:31:02in v1 from right bundle to left bundle
- 00:31:05type that means you have lost left
- 00:31:06bundle
- 00:31:07and this is a proof that you had left
- 00:31:09bundle to begin with
- 00:31:10and this is a response to this
- 00:31:12diagnostic of uh reaching the endpoint
- 00:31:14you will see
- 00:31:15that the keywords will change from uh
- 00:31:18narrow
- 00:31:19and short time to peak in v6 to
- 00:31:23long time in in total peak in v6
- 00:31:28you will see all many different
- 00:31:30morphological changes
- 00:31:33and much nicer response also diagnostic
- 00:31:37is a selective response for example here
- 00:31:39how did we get the selective response
- 00:31:41this
- 00:31:42despite sometimes that refractoriness of
- 00:31:44left bundle is longer
- 00:31:46how is that possible is it possible by
- 00:31:49using a different facing protocols for
- 00:31:51example here a
- 00:31:52very long cycle length of the intrinsic
- 00:31:55rhythm
- 00:31:56makes the refractoriness of the
- 00:31:59myocardial tissue quite long and then
- 00:32:02you
- 00:32:02provide first premature which shortens
- 00:32:05the refractoriness
- 00:32:07but only of the left bundle not of the
- 00:32:09myocardium
- 00:32:10because the myocardium needs many cycles
- 00:32:12to shorten refractoriness while the
- 00:32:14conduction system needs just one cycle
- 00:32:16to shorten the fracturings
- 00:32:18so the next premature will find the
- 00:32:20myocardium refractory
- 00:32:22and left bundle responsive and you will
- 00:32:24have a selective response
- 00:32:26with this typical full-blown right-bound
- 00:32:29launch block pattern the shovel-like
- 00:32:31deflection instead of small deflection
- 00:32:33at the end of d1
- 00:32:34and you will have a selective response
- 00:32:36which is very
- 00:32:37elegant way to prove that you have a
- 00:32:39left bundle branch block capture
- 00:32:42so that technique we use
- 00:32:45if it's not working because sometimes
- 00:32:48you can't really see the difference in
- 00:32:49refractoriness
- 00:32:50then we use more advanced facing
- 00:32:52protocols and you see an example of that
- 00:32:54here
- 00:32:55we publish that in jc for example here
- 00:32:57you see a fast drive
- 00:32:5810 opposed to increase the refractories
- 00:33:00of blood bundle and then
- 00:33:02myocardial response we don't
- 00:33:05have time to go into details but it's
- 00:33:08based on very simple physiology
- 00:33:10that you should know if you want to be
- 00:33:14successful in using program stimulation
- 00:33:16or valid branch pacing
- 00:33:18and once you have that once you have
- 00:33:20confirmation of the bundle branch
- 00:33:22capture
- 00:33:22that's the end of it all you need to do
- 00:33:24right now is to
- 00:33:26put the device into the pocket close the
- 00:33:28incision and go home
- 00:33:30because rest is a quite standard
- 00:33:32procedure
- 00:33:34so that's the way i do it thank you very
- 00:33:36much
- 00:33:38thank you marek that was excellent uh
- 00:33:41it's
- 00:33:42brilliant to have that sort of insight
- 00:33:44into
- 00:33:45into left bundle branch area pacing
- 00:33:48um some questions i mean i actually i
- 00:33:52tend to use the steerable catheter
- 00:33:55by default actually i find that
- 00:33:58it gives you more support uh i put the
- 00:34:01035 wire through the
- 00:34:04through the guide and get into
- 00:34:07the right ventricle uh very easily uh
- 00:34:10and then remove the wire and then i can
- 00:34:13use contrast now
- 00:34:14i i i find contrast useful actually um
- 00:34:18so as you screw in the lead you can use
- 00:34:21a little bit of contrast
- 00:34:23uh in the steerable catheter that will
- 00:34:26give you
- 00:34:27uh what will tell you um that you're up
- 00:34:31about the distance between your
- 00:34:33opposition to the septum
- 00:34:35and how far the lead has gone through
- 00:34:37particularly on the
- 00:34:38lao um i also find that
- 00:34:42i mean sometimes this these procedures
- 00:34:46are done
- 00:34:47as a redo as you know a salvage
- 00:34:49procedure
- 00:34:50and you have to go from the right i also
- 00:34:53find that this theorem
- 00:34:55is is good what are your thoughts about
- 00:34:58this theorem rather than the pre-shaped
- 00:35:01i would love to have a steerable sheet
- 00:35:03that is
- 00:35:04good enough to use it the the sheet that
- 00:35:07has
- 00:35:08um separate curves apart from the
- 00:35:11rv curve and we do not have that we have
- 00:35:14only
- 00:35:15304 that we use occasionally for the his
- 00:35:18bundle pacing this is terrible we do not
- 00:35:20have the
- 00:35:20steerable with the second care of the
- 00:35:22separate caf which is
- 00:35:24available in some countries but not in
- 00:35:27poland
- 00:35:28and i do not have experience with that
- 00:35:30certainly the future
- 00:35:32um belongs to this derivative i agree
- 00:35:34with you
- 00:35:36paul what's your um experience with the
- 00:35:39steerable rather than the pre-shaped
- 00:35:41the tendency is the pre-shaped catheter
- 00:35:43as the um
- 00:35:45first choice and usually gone to the
- 00:35:48steerable where we've had difficulties
- 00:35:50so
- 00:35:50um i think it's just what i'm familiar
- 00:35:52with i was interested in marek's comment
- 00:35:55about the screw beads
- 00:35:57and just wondered how often you see
- 00:35:59those mark when you're
- 00:36:00doing left bubble implantation well at
- 00:36:03the beginning when i
- 00:36:04was not looking at them actively i just
- 00:36:07upset them from time to time but
- 00:36:09right now i actually doing a research on
- 00:36:12that
- 00:36:12and i have to tell you that it's present
- 00:36:14in over 90
- 00:36:16of the cases and in nearly 100 of the
- 00:36:19successful sites
- 00:36:20so it's always there if you don't see
- 00:36:22screw bits the chances that you are
- 00:36:24there are very small on the other hand
- 00:36:26when you see them
- 00:36:26this is 100 certain that you are there
- 00:36:30so they are always there look at your
- 00:36:31procedures if you have them recorded
- 00:36:34look at them you will be surprised that
- 00:36:36where they were always there sometimes
- 00:36:38one bit that you missed but it was there
- 00:36:42also marek the the other question is
- 00:36:45scar
- 00:36:46so some authors have uh placed
- 00:36:49some hope in the
- 00:36:52um in the notion that we can circumvent
- 00:36:55scar
- 00:36:55with left thunder branch area facing or
- 00:36:58even his pacing as opposed to crt
- 00:37:00which as you know there is some evidence
- 00:37:02to show that if you pace
- 00:37:04uh scar it um it's suboptimal
- 00:37:08but actually uh pacing a septal scar
- 00:37:11which is very common particularly in
- 00:37:12patients who have had a
- 00:37:14an lady infact um it's all
- 00:37:17it's likely to be also a problem
- 00:37:21do you have any views about scar in
- 00:37:24relation to
- 00:37:26positions or the screwing or the
- 00:37:29stability i'm
- 00:37:33not sure what causes the entanglement
- 00:37:35effect this is why
- 00:37:36sometimes you can't really progress with
- 00:37:38the lead and i think that apart from
- 00:37:40some kind of
- 00:37:41you know panzer myocardium endocardium
- 00:37:44this car might be the answer
- 00:37:46if you have a very fibrous scale scar on
- 00:37:49the
- 00:37:50septum you may not be able to progress
- 00:37:52with the lead
- 00:37:53and then you need to go slightly deeper
- 00:37:55to find the area or you can go deep into
- 00:37:57the septum do not fight with a very
- 00:37:59dense scalp
- 00:38:00but if you go into this car and i think
- 00:38:02i did that a few times
- 00:38:04then you might be surprised that the
- 00:38:06cures is very handy
- 00:38:08you are on the left side and you
- 00:38:11are not happy with the cures because
- 00:38:13there is simply no
- 00:38:15a life conducting tissue and you are
- 00:38:18capturing some
- 00:38:19a few microfibers that are there but the
- 00:38:22cures is poor
- 00:38:23and if you go further down the road you
- 00:38:26will have a nicer cures actually
- 00:38:28that's my observation you know these few
- 00:38:31cases when i
- 00:38:32did this so marek with
- 00:38:35uh bradley pacing uh how
- 00:38:38how how are you um dealing with this are
- 00:38:42you putting
- 00:38:42an rb leading as well or
- 00:38:46two leads or are you just leaving the
- 00:38:48the
- 00:38:49left bundle lead well i
- 00:38:53my lab completely converted to
- 00:38:54conduction system basically we did not
- 00:38:56do rv pacing for an indication apart as
- 00:38:59a bailout for if
- 00:39:00everything else fails so we start with
- 00:39:02the hiss we don't play with
- 00:39:04it too long if it's not there just go
- 00:39:06for the left bundle
- 00:39:07and finish the procedure and all
- 00:39:09procedures
- 00:39:10regardless of the indication is it's crt
- 00:39:13heart failure
- 00:39:14or just sick sinus or heavy blood will
- 00:39:16receive a conduction system facing
- 00:39:18even the youngest residents who did
- 00:39:21start
- 00:39:22this year pacemaker implantation they do
- 00:39:24not learn the classic technique they
- 00:39:26only do conduction system pacing it can
- 00:39:28be done by inexperienced operators it's
- 00:39:30a
- 00:39:30technique that is quite easy actually
- 00:39:34i'm sorry are we paid no rv leads to
- 00:39:36answer your question
- 00:39:37no no needs classic no and paul was your
- 00:39:40practice
- 00:39:42uh currently we are doing a fair amount
- 00:39:44of hispanic placing
- 00:39:45uh for um patients of first degree av
- 00:39:49blog
- 00:39:49or nara cures complete heart blog
- 00:39:54well we're still i guess waiting for
- 00:39:57randomized clinical trials to be
- 00:39:59absolutely certain that um we
- 00:40:03it is the right thing to do for every
- 00:40:04patient are you worried about
- 00:40:06uh pacemaker dependency in these
- 00:40:09patients
- 00:40:11in the patients who are having hispanic
- 00:40:12system uh i mean
- 00:40:14that is a potential problem we always
- 00:40:16check that
- 00:40:17we have one-to-one conduction
- 00:40:21when we when we pace at high outputs uh
- 00:40:25higher sorry at some high rates um
- 00:40:28and we check the hpv interval well i
- 00:40:30think
- 00:40:31um this is being uh very helpful um
- 00:40:35i i i it's a very nice explanation of
- 00:40:38the
- 00:40:38technique i'm very grateful to uh
- 00:40:41professor gerzerski
- 00:40:42and to dr paul foley for this session
- 00:40:45which i i hope that you find
- 00:40:49very useful i certainly did many things
- left bundle branch pacing
- conduction system pacing
- bradycardia
- heart failure
- pacemaker
- lead placement
- physiological pacing
- his bundle
- cardiac resynchronization
- medical technology