#AIMI23 | Panel: Industry Perspectives of Health AI in 2023
概要
TLDRIn this video, experts from various fields discuss the integration of AI in healthcare, focusing on the enhancements it can bring to patient care and clinical workflows. Key speakers emphasize the importance of collaboration among technology, life sciences, and healthcare practitioners to overcome challenges in AI implementation. Topics include regulatory hurdles, business models for sustainable AI solutions, and the potential of open-source frameworks in fostering innovation. The discussion highlights the need for robust algorithms that can handle diverse medical data and the future of multimodal systems in improving clinical outcomes.
収穫
- 👩⚕️ AI is set to significantly improve patient outcomes in healthcare.
- 📈 Effective business models are crucial for AI solutions to thrive in a B2B environment.
- 🔍 Regulatory compliance remains a critical challenge in deploying AI technologies.
- 🌍 Open source can accelerate medical AI research and innovation.
- 🤝 Collaboration between academia and healthcare practitioners enhances algorithm validation.
- 🚀 Multimodal systems show promise in integrating various data types for comprehensive clinical support.
- 💡 AI deployment requires understanding user needs and minimizing implementation challenges.
- 🧠 Sustainable AI solutions can generate financial value for healthcare providers.
- 🎯 The future of AI in healthcare includes opportunities in developing regions and underserved markets.
- 🔄 Continuous algorithm validation is necessary to ensure efficacy as new data emerges.
タイムライン
- 00:00:00 - 00:05:00
Jessica Mega, a cardiologist at Stanford and co-founder of Verily, highlights the intersection of technology and life sciences to improve patient outcomes, reminiscent of the excitement during the human genome project, and emphasizes the need for collaboration to bridge the gap between advancements and practical applications in healthcare.
- 00:05:00 - 00:10:00
Rohit Takar from Carpool discusses the challenges in implementing AI in medical imaging, especially regarding presenting solutions to radiologists and monitoring deployed solutions for model drift and data drift over time, emphasizing the need for collaborative efforts to overcome these challenges.
- 00:10:00 - 00:15:00
Tanishq Abraham, a healthcare investor at F Prime, stresses the focus on early-stage opportunities that improve clinical processes and enable tasks currently beyond clinician capabilities, highlighting the transformative potential of AI in healthcare.
- 00:15:00 - 00:20:00
Stephen Drew of Wing Brain describes the mission of his company to improve radiology workflows through AI, while also addressing significant public health issues like tuberculosis and emphasizing the importance of data integration across healthcare systems to enhance diagnostic accuracy.
- 00:20:00 - 00:25:00
Nish from Bunker Hill shares how they aim to facilitate the transition of algorithms from research to clinical practice by creating a consortium of research institutions to validate, commercialize, and share revenue from successful algorithms, addressing the gap between research innovations and real-world applications.
- 00:25:00 - 00:30:00
Tanishq from Stability AI expresses excitement over generative AI's applications in medicine, particularly in creating models that enhance research and practice through the exchange of ideas and collaborations between general AI and medical AI fields.
- 00:30:00 - 00:35:18
Panel discussion reveals critical reflections on sustainable business models in healthcare AI, focusing on demonstrable clinical value for providers, operational efficiency improvements, and the need for AI solutions to be embedded in existing processes to gain acceptance and financial backing from healthcare stakeholders.
マインドマップ
ビデオQ&A
What is the current state of AI in healthcare?
AI in healthcare is at a critical juncture, with many technical advancements leading to applications aimed at improving patient outcomes.
What challenges exist in deploying AI in clinical workflows?
Challenges include implementation strategies to fit user needs, monitoring AI models for drift, and addressing regulatory requirements.
How do companies plan to monetize their AI solutions in healthcare?
Monetization strategies include getting reimbursement from payers, improving clinical value, and tapping into healthcare data markets.
What role does regulatory compliance play in AI healthcare solutions?
Regulatory compliance is essential for AI deployment in healthcare, ensuring safety and efficacy while navigating processes like FDA approvals.
What potential does open source have in medical AI?
Open source can accelerate research and allow collaboration, facilitating the development of models tailored to specific healthcare applications.
What is the importance of multimodal systems in medical AI?
Multimodal systems integrate various data types to provide comprehensive support to clinicians, enhancing decision-making processes.
How can AI be scaled across diverse medical findings?
Scaling AI across multiple findings requires effective regulatory processes, minimizing redundancy in approvals and ensuring comprehensive coverage.
What business models are proving effective for AI in healthcare?
Effective models include software as a service, generating direct financial value for providers, and integrating AI into existing healthcare workflows.
What are the future prospects for AI in healthcare?
Future prospects include advancements in multimodal AI systems and opportunities in underserved regions, focusing on AI's applicability to diverse healthcare scenarios.
How do researchers approach validation for AI algorithms?
Validation involves external testing, clinical ROI assessment, and establishing partnerships across academic institutions for data sharing.
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- 00:00:04my name is Jessica Mega I'm a
- 00:00:07cardiologist at Stanford I'm on the
- 00:00:10board of directors at danaher
- 00:00:11Corporation and one of the co-founders
- 00:00:12of verily which is the branch of
- 00:00:15alphabet really focused on life science
- 00:00:17and Healthcare
- 00:00:18and personally my passion has always
- 00:00:21been thinking about the intersection of
- 00:00:23Technology life science and the
- 00:00:25applications to improve patient outcomes
- 00:00:27and I think we're in a moment that
- 00:00:28Harkens back in my mind to when the
- 00:00:31human genome was sequenced and if you
- 00:00:33think about all of the Decades of
- 00:00:35research and all of the deep insights
- 00:00:38that it took to sequence the human
- 00:00:40genome there were many many people many
- 00:00:43tools but it was then the next several
- 00:00:45decades of applications the
- 00:00:47understanding of what genes do we
- 00:00:49actually have to measure when we think
- 00:00:50about oncology and Diagnostics what does
- 00:00:53it translate now we're applying direct
- 00:00:55crispr therapies but we're in that same
- 00:00:57moment of excitement where there have
- 00:00:59been Decades of technical advancements
- 00:01:01and we have some of the world's experts
- 00:01:03with us today to talk about that but now
- 00:01:05we're in that critical moment of
- 00:01:07application and we heard from Nigam that
- 00:01:09there's a Chasm and I think collectively
- 00:01:11this group together can help bridge that
- 00:01:13Chasm and I think take all of the
- 00:01:16opportunity but also all the reality of
- 00:01:18what it takes to truly create a business
- 00:01:20in this world
- 00:01:22as I am going to turn to our group we're
- 00:01:24going to have each individual introduce
- 00:01:26themselves the company that they're
- 00:01:27working with and any high level thoughts
- 00:01:29and then what we're going to do is I
- 00:01:31have a few questions prepared but I know
- 00:01:33that your questions are on your mind
- 00:01:35because people have already grabbed me
- 00:01:37in the hallway and started questions so
- 00:01:38uh start to keep those in your mind as
- 00:01:41we get the introductions because I
- 00:01:42promise they'll be time for uh for all
- 00:01:44of your questions all right if uh if you
- 00:01:46don't mind started
- 00:01:48hi everyone my name is Rohit takar I
- 00:01:51head the technology at carpool so
- 00:01:53carpool is a platform that allows you to
- 00:01:55explore validate and deploy Medical
- 00:01:57Imaging AI Solutions in your clinical
- 00:01:59workflow I think we all believe that AI
- 00:02:04how can improve the patient outcomes
- 00:02:06stream streamline the processes and can
- 00:02:09help reduce the cost but what are the
- 00:02:11challenges that we are facing right now
- 00:02:12so I believe that there are two
- 00:02:14challenges uh that I feel ah that are
- 00:02:17actually handling the deployment of AI
- 00:02:20uh in clinic clinical workflow one is
- 00:02:23the implementation so how do you present
- 00:02:26these solutions to the end users which
- 00:02:28in our case are Radiologists so ah there
- 00:02:31could be multiple solution because one
- 00:02:33fits for all ah it doesn't happen the
- 00:02:36other is once you have deployed a
- 00:02:38solution so how do we monitor it over
- 00:02:40time so there could be model drift data
- 00:02:42drift and there would be some issue with
- 00:02:45the pipeline so these are the two
- 00:02:47challenges that I feel uh which ah we
- 00:02:50need to figure out together as a
- 00:02:52collaborative effort and see how can we
- 00:02:55build Solutions create proof points and
- 00:02:58then deploy them in uh on a wider ah at
- 00:03:02a clinical level so that's what I feel
- 00:03:06could be something that we can do in
- 00:03:082023
- 00:03:10thank you
- 00:03:12hi I'm ten viewers either Mahmoud I'm an
- 00:03:14IBM fellow at IBM research IBM research
- 00:03:17as you know is the academic wing of IBM
- 00:03:20where we our Charter is to explore the
- 00:03:22Next Generation Technologies in various
- 00:03:24fields in healthcare in particular as
- 00:03:27you know we were
- 00:03:28you know ahead of the curve in trying to
- 00:03:31realize the importance of AI and
- 00:03:32radiology and some of you have been to
- 00:03:35RSA 2016 or 2015 onwards you've seen the
- 00:03:39introduction of AI in Radiology it
- 00:03:42transitioned into business so we've gone
- 00:03:43through the cycle of you know the hype
- 00:03:47and practicing putting it in
- 00:03:50products and then coming back to the
- 00:03:52realization of what is the next things
- 00:03:54to do and so I will have some
- 00:03:56perspectives on now what works what
- 00:03:58doesn't work and where are the
- 00:04:00challenges particularly when it comes to
- 00:04:02looking at capturing fine-grained
- 00:04:05nuances which is where the AI needs to
- 00:04:08get to in Next Generation models
- 00:04:12okay my name is cu I'm a healthcare
- 00:04:15investor at F Prime which is a venture
- 00:04:18capital group mostly based in Boston SF
- 00:04:20and London but before that I'm a
- 00:04:23Stanford Medical School alumni and also
- 00:04:25did research at the Stanford machine
- 00:04:27learning grouping AI for healthcare as
- 00:04:28well and I think right now we're looking
- 00:04:30at a lot of early stage opportunities
- 00:04:32with people with ideas on twofolds one
- 00:04:36is actually similar to the previous
- 00:04:38panel talk about speeding up a lot of
- 00:04:41the processes that we encounter in the
- 00:04:43clinic you know managing the back office
- 00:04:45for clinicians and whatnot and the other
- 00:04:47side is actually a step forward to to do
- 00:04:51things that clinicians cannot do right
- 00:04:53now and that's an area that we also look
- 00:04:56at currently too
- 00:04:59so good morning
- 00:05:01good morning
- 00:05:03good morning
- 00:05:04you know what I said that to weigh me up
- 00:05:06because I just fly from the other side
- 00:05:08of the Earth from Vietnam to here so so
- 00:05:12you guys just remember a Vietnamese guy
- 00:05:14on the stage so that's me so
- 00:05:16so I'm Stephen Drew I'm the guy for big
- 00:05:21brain
- 00:05:22so Wing brain is a company around four
- 00:05:25years and you know one day I told my
- 00:05:29boss a secretive in Microsoft say I'm
- 00:05:32not going to do any more Microsoft stuff
- 00:05:35I want to do something
- 00:05:37a little bit more Humanity so I decided
- 00:05:41to get into this field to build AI
- 00:05:44to assist grade watches
- 00:05:47on the workflow
- 00:05:49and improving the efficiency like most
- 00:05:52people said and also the by through
- 00:05:55spending and also through the
- 00:05:58misdiagnosis in cancer area
- 00:06:02and then also we do the social impact we
- 00:06:06just like dealing with tuberculosis so I
- 00:06:09went to MetLife who you know a few
- 00:06:12months ago in Geneva tried to tackle
- 00:06:15that problem in other side of the world
- 00:06:18so basically Wing brain is focusing on
- 00:06:22religious workflow we have 52 you know
- 00:06:26comprehensive detection
- 00:06:29and at the same time we realized that
- 00:06:32not just AI we need to focusing on the
- 00:06:36Enterprise side which is where we
- 00:06:39connect all of the data together because
- 00:06:41you know that hospital have risk lists
- 00:06:43his love of law so they vary this very
- 00:06:48so we bring the connector to bring the
- 00:06:50data together and we can train
- 00:06:53Ai and we also one of the guys that
- 00:06:57interray the activity and all of that
- 00:07:00into the workflow so we can improve the
- 00:07:02reporting as well and the data
- 00:07:05extraction from
- 00:07:07La language model for the medical field
- 00:07:10so with this I'm really looking for a
- 00:07:14lot of questions about like you know on
- 00:07:17how we really deployed to a hundreds
- 00:07:19Hospital you know the way we built is
- 00:07:22two year we never do anything else
- 00:07:24except just helped out to be a decent
- 00:07:27product and the third year we go from 10
- 00:07:29to 20 to 100 hospital and today we
- 00:07:33affect around 2 million people live
- 00:07:35through our Pipeline and we have a FDA
- 00:07:40you know one of the only one in the
- 00:07:42region of Southeast got that and as well
- 00:07:45we assign agreement with Microsoft
- 00:07:48Nvidia and also stand for so great to
- 00:07:53work with curl every two weeks we see
- 00:07:55his face on life so thank you very much
- 00:07:59and great to see all of you again
- 00:08:02hi everyone my name is Nish I'm the CEO
- 00:08:05of Bunker Hill previously the starting
- 00:08:07Bunker Hill I was a student at Stanford
- 00:08:09I was a graduate researcher at the
- 00:08:11Stanford Amy group actually and Dr
- 00:08:14nigamsha mentioned that there were many
- 00:08:15algorithms that are being built I'm
- 00:08:16pretty sure my algorithm was one of
- 00:08:18those in the tally there and you know
- 00:08:21after we built those algorithms we
- 00:08:23really stumbled stumbled hard on the
- 00:08:25question what now
- 00:08:27okay you know what the steps are you
- 00:08:29know you need to externally validate
- 00:08:31your algorithm you know you need to show
- 00:08:32that it has some kind of clinical Roi
- 00:08:34you know you need FDA clearance you know
- 00:08:36you need to deploy but for all of those
- 00:08:38phases for all of those questions you
- 00:08:41had two pressing problems one I don't
- 00:08:43even know what it takes to get there too
- 00:08:46I don't even know where to start and we
- 00:08:48see this as a pressing problem you know
- 00:08:50the only way algorithms are hopefully
- 00:08:53going to get out into the clinical
- 00:08:54practice if you're able to take
- 00:08:56researchers algorithms and actually have
- 00:08:58a way to get them into practice the
- 00:09:01current solution of starting a company
- 00:09:03around a single algorithm and hoping to
- 00:09:05get Venture funding is just not working
- 00:09:07and so what we do at Bunker Hill is that
- 00:09:11we are creating a way to get algorithms
- 00:09:14built by the broader research Community
- 00:09:16out into the clinical world we have
- 00:09:18built a Consortium of academic medical
- 00:09:20centers which is effectively a legal
- 00:09:22bubble there are 17 academic medical
- 00:09:24centers a part of this today and what
- 00:09:26this allows them to do is researchers at
- 00:09:28each other researchers can collaborate
- 00:09:30across institutions share data share
- 00:09:32algorithms validate each other's
- 00:09:34algorithms and when they are validated
- 00:09:36Bunker Hill files for FDA clearance
- 00:09:38commercializes it on a platform and then
- 00:09:40shares the revenue back with the
- 00:09:41researcher hopefully that creates a way
- 00:09:43to actually get all of the one wonderful
- 00:09:46research work that is being done by such
- 00:09:48daring innovators and actually getting
- 00:09:50them into clinical practice and making
- 00:09:52AI actually a reality
- 00:09:56hi my name is tanishq Abraham and I'm a
- 00:09:59researcher at stability Ai and
- 00:10:02previously I was also a PhD student at
- 00:10:06UC Davis and just recently completed and
- 00:10:10yeah at stability AI I work on medical
- 00:10:13AI research in fact we founded an
- 00:10:15organization known as medarc to help
- 00:10:17accelerate some of this medical AI
- 00:10:20research especially looking at the
- 00:10:22intersection of generative Ai and
- 00:10:24medicine so of course you know we've
- 00:10:26heard a lot about that already today but
- 00:10:28yeah we're really excited about about
- 00:10:30what we can how we can apply a
- 00:10:32generative AI to Medicine especially at
- 00:10:34a company like stability which is known
- 00:10:35for their efforts in that space with you
- 00:10:38know the famous stable diffusion image
- 00:10:40generator and you know there are very
- 00:10:42surprising and interesting applications
- 00:10:44of of generative Ai and you know you
- 00:10:46never think like something like an image
- 00:10:48generator you know what kind of
- 00:10:49applications it could have in medicine
- 00:10:51but it turns out you know there's some
- 00:10:53really interesting applications and I
- 00:10:56think also one of the really exciting
- 00:10:58things about working in medical AI
- 00:10:59research is also the exchange just yeah
- 00:11:01generally the exchange of ideas uh in
- 00:11:04just the general AI field but also and
- 00:11:07with you know medical AI I I think um
- 00:11:09you know of course there's lots of
- 00:11:10applications of various AI Technologies
- 00:11:14in medicine but also lots of interesting
- 00:11:16applications of methods that were
- 00:11:19originally developed in medical Ai and
- 00:11:21bringing them to kind of the general AI
- 00:11:23uh uh Fields so I mean we've seen some
- 00:11:26of these examples in the past for
- 00:11:27example the unit was originally
- 00:11:29developed for you know biomedical
- 00:11:31segmentation even clip which was you
- 00:11:34know which was developed by open AI it
- 00:11:36was kind of a scaled up version of a
- 00:11:38paper that was originally published by
- 00:11:40Stanford Amy actually so there's lots of
- 00:11:42interesting applications in general AI
- 00:11:44that kind of start out in some of the
- 00:11:48medical AI research so I think that sort
- 00:11:50of collaboration that sort of exchange
- 00:11:52of ideas is really exciting and I think
- 00:11:55yeah the sort of development in parallel
- 00:11:57of ideas in general AI generative AI
- 00:12:00medical AI That's what I'm most excited
- 00:12:02about
- 00:12:03excellent and congratulations
- 00:12:05so we were talking about the business
- 00:12:07models how do we actually create
- 00:12:10sustainable businesses and if you think
- 00:12:12about outside of the healthcare space a
- 00:12:15lot of the AI is embedded in tools where
- 00:12:17there's already an ad model or there's a
- 00:12:20freemium model where you start but you
- 00:12:22pay for additional services or to direct
- 00:12:25to Consumer so you if we can start with
- 00:12:27you what are some of the business models
- 00:12:29that you're seeing that are effective in
- 00:12:31healthcare because in many cases it's a
- 00:12:33B2B right so you're an industry selling
- 00:12:35to someone else who is paying for health
- 00:12:37care who are ultimately serving the
- 00:12:40customer our constituents patients and
- 00:12:42clinicians so it'd be good to just hear
- 00:12:44a little bit about how you evaluated
- 00:12:46businesses and then we'll hear from a
- 00:12:48few of the companies what business
- 00:12:49models are working and potentially if
- 00:12:51any of them haven't worked yeah
- 00:12:53definitely I think that's an era that
- 00:12:55I'm also learning as well so I would
- 00:12:57love to hear other people's ideas too so
- 00:12:59I think we see a couple of different
- 00:13:01ways people try to get paid and I was
- 00:13:03previously mentioned by other people as
- 00:13:05well on the provider side either as
- 00:13:07hospitals or clinicians the margin is
- 00:13:10quite thin right like there's not as
- 00:13:12much of Liberty to just pay for hundreds
- 00:13:15of thousands of dollars of software as
- 00:13:17what other companies can pay for even
- 00:13:20just one single user so one way we've
- 00:13:23seen people trying to get around that is
- 00:13:25to not just create clinical value from
- 00:13:27their product but also direct monetary
- 00:13:31value from their AI product to for
- 00:13:34example to get it reimbursed from the
- 00:13:37payer side for providers so that
- 00:13:39provider is not just using it to get out
- 00:13:42of their own pocket but also actually
- 00:13:44create hopefully Financial value
- 00:13:46directly for them as well another way
- 00:13:49that we see this being monetized is
- 00:13:51actually to go beyond the direction to
- 00:13:54patient with back to clinicia angle but
- 00:13:57also to tap into the broader Healthcare
- 00:13:59ecosystem people who tap into the
- 00:14:02healthcare data market which is huge and
- 00:14:04you know companies pay hundreds of
- 00:14:06Millions for for that in some ways and
- 00:14:08also other sides of the healthcare
- 00:14:11ecosystem as well which sometimes can
- 00:14:13have more Liberty in trying out and
- 00:14:16paying for these type of AI Solutions
- 00:14:18and from some of the company's
- 00:14:20perspectives
- 00:14:21what are the models that you're using I
- 00:14:23can take a stab at it
- 00:14:25um I think their business model it
- 00:14:28implies money and I think that's where
- 00:14:30AI just reduces down to any other
- 00:14:32medical intervention you just have to
- 00:14:34follow the money so if you look at who
- 00:14:36the healthcare stakeholders are okay so
- 00:14:38you have providers the health systems
- 00:14:40you have Pharma and then you have payers
- 00:14:42on the provider side what can you do to
- 00:14:44make a financial case for them okay
- 00:14:46could you find them more patients could
- 00:14:47you reduce or automate away mundane or
- 00:14:50boring or expensive tasks okay so if you
- 00:14:52can do that there's a business incentive
- 00:14:55there's a financial incentive for the
- 00:14:57providers to adopt it and actually pay
- 00:14:58for it on the on the Pharma side can you
- 00:15:01accelerate their clinical trials by
- 00:15:03finding patients faster if you can do
- 00:15:05that there's a business case for them
- 00:15:06there's money to be saved by them can
- 00:15:08you find more patients who would be
- 00:15:10eligible for drugs that they just came
- 00:15:12out with okay now that's again you're
- 00:15:13increasing the market that's a business
- 00:15:15model on the insurance side on the peer
- 00:15:18side can you reduce their cost of care
- 00:15:20within two years okay that's another
- 00:15:21incentive there's a there's a financial
- 00:15:23uh play for them so again in this case
- 00:15:26AI just reduces down to any other
- 00:15:28medical intervention it does not really
- 00:15:29matter what technology is supporting
- 00:15:32that intervention ultimately it's who is
- 00:15:34being who financially benefits from the
- 00:15:37widespread deployment of that tool so
- 00:15:39Stephen yes so I think uh I go back to
- 00:15:43the paying the pain point of hospital
- 00:15:45and the operation of the hospital so as
- 00:15:50you know that in my point of view the
- 00:15:52hospital uh you know I.T is uh probably
- 00:15:57not as strong at the order vertical
- 00:16:00market like you know e-commerce supply
- 00:16:03chain manufacturing so we come down to
- 00:16:06not only using the AI to increasing the
- 00:16:10efficiency
- 00:16:12misdiagnosis you know showing the TB
- 00:16:15problem of the world we also look
- 00:16:17looking at how to really solving the
- 00:16:19pain of data display and data platform
- 00:16:23and combined with the AI we can connect
- 00:16:26on the data and generate the analytic
- 00:16:29and forecasting for the operational as
- 00:16:32well as for the doctor in efficiency so
- 00:16:35you can think of the the model business
- 00:16:37we do a software as a service because we
- 00:16:40like to be more like TurnKey solution
- 00:16:43comprehensive solution rather than
- 00:16:45single POI solution and we tackle from
- 00:16:48two Dimension One is the Enterprise that
- 00:16:52we can connect all of the display data
- 00:16:54into the center line with the identifier
- 00:16:57model the second is the AI to bring the
- 00:17:00value of efficiency and the third
- 00:17:03dimension we do is the monetization of
- 00:17:05AI so we view a platform to do the
- 00:17:08labeling annotation for all of the
- 00:17:11company Wai because we know Wing brain
- 00:17:14cannot do everything so that's why we
- 00:17:16bring you know the monetization AI not
- 00:17:20only from labeling and speak up with
- 00:17:22hundreds of pre-latches it's very hard
- 00:17:24in the U.S to get 100 languages to do
- 00:17:27the labeling you know of course we have
- 00:17:29to define the standard of how to do the
- 00:17:32label correctly and then we're doing
- 00:17:34that so we build those platforms not
- 00:17:37only for solving the doctor and the
- 00:17:40workflow also we're doing with the
- 00:17:42labeling and then the third dimension we
- 00:17:45also want to make sure that like you
- 00:17:47know sharing the data to the communities
- 00:17:50in the public matter so that we can
- 00:17:53solve the problem together and
- 00:17:55Marketplace our platform any other
- 00:17:58thoughts maybe I can give the other end
- 00:18:00of the spectrum perspective from a large
- 00:18:02company and why we got out of the
- 00:18:04healthcare business
- 00:18:05so um
- 00:18:07you know the the kind of Revenue that
- 00:18:09makes sense uh for IBM a billion dollar
- 00:18:12revenue is still not good enough so so
- 00:18:14this field and and just by AI alone uh
- 00:18:19surviving is more for the smaller
- 00:18:22businesses that's why you saw so many
- 00:18:24startups in this space but as the
- 00:18:25starters have also discovered just
- 00:18:28having an AI model alone is not enough
- 00:18:30it is only a small piece of the big
- 00:18:32puzzle that you have to get into so if
- 00:18:35you think of what are some good models
- 00:18:36for Success that where AI will still
- 00:18:38succeed and where we see a future for it
- 00:18:41will be in a few different deployments
- 00:18:43situations one and I remember there's
- 00:18:45Intel Inside there's like I think terms
- 00:18:48that you see on your laptops uh it
- 00:18:51should be something like that where it's
- 00:18:53the other thing that in which AI is
- 00:18:56built into that is giving the value
- 00:18:58proposition whether that is Hardware in
- 00:19:01which you have ai doing this naturally
- 00:19:02or is in the packs where it's already
- 00:19:04built in and it's not being charged
- 00:19:06separately so the way you win in this
- 00:19:09might be through those vehicles and then
- 00:19:12having some attribution back to aisl but
- 00:19:15AI by itself
- 00:19:16is not something that people will be
- 00:19:19willing to pay big bucks for and that
- 00:19:21was one of the learnings as such the
- 00:19:24other thing I could say is and and I
- 00:19:26mean if you've heard of the think and
- 00:19:28what's the next announcement recently
- 00:19:29and all we are big into AI models still
- 00:19:31but the way we're looking off is the
- 00:19:34value proposition is using those for
- 00:19:36some use cases and so the AI is again
- 00:19:39built inside and it's not the focus but
- 00:19:42it's the end user use case that is the
- 00:19:44focus and there there is opportunities
- 00:19:46in Consulting in you know in those sort
- 00:19:49of methods of deployment so bundle
- 00:19:52inside is one way and I think we can
- 00:19:55still make a business case for AI
- 00:19:59so I think ah
- 00:20:02the biggest question that we get is who
- 00:20:04will pay for the implementation of AI
- 00:20:07right so whether the radiology
- 00:20:09department the hospital or will you cut
- 00:20:11it from the radiologist pocket so that
- 00:20:13these are some of the questions that we
- 00:20:14get
- 00:20:15uh I think if you can do an Implement a
- 00:20:18implementation where we can really
- 00:20:20augment the Radiologists so if let's say
- 00:20:22they are doing 100 scans and they are
- 00:20:24paid X dollars for that
- 00:20:26at some point they can do more than 100
- 00:20:28scans and by implementation of AI let us
- 00:20:33say so AI Solutions you can get for 30
- 00:20:35cents 20 cents for 40 cents per study so
- 00:20:39if you can uh give them a value that is
- 00:20:41X Plus Delta so I think that would be
- 00:20:44something that can be that can come from
- 00:20:46the radiologist pocket as well so those
- 00:20:48are the business cases that we are
- 00:20:49actually trying right now the other is
- 00:20:51how can you get more patients so ah from
- 00:20:54your x-rays to CD scans can you convert
- 00:20:57more patients which need
- 00:20:59CT scans to be done so I mean that could
- 00:21:03be the other way
- 00:21:05businesses wants to ah see the value
- 00:21:09coming in yeah so it sounds like there
- 00:21:11are two major themes that are coming
- 00:21:13together one is this idea if you think
- 00:21:15about life science and Healthcare there
- 00:21:16are already models out there so if you
- 00:21:18can accelerate drug Discovery if you can
- 00:21:20increase efficiency and value leverage
- 00:21:24those models and the second one that can
- 00:21:26be really emphasized is that the AI is
- 00:21:29the one piece surrounded by all of the
- 00:21:31services and just think holistically I
- 00:21:33think about the offering so I think
- 00:21:35those are just good reminders I mean I
- 00:21:37did want to add that it is possible if
- 00:21:40AI could simply be that a reason for a
- 00:21:43business if AI had that capability right
- 00:21:45now the current models can only do touch
- 00:21:49some portion of this like think about
- 00:21:50chest x-ray work there's still like 4 14
- 00:21:5214 findings I mean what about the rest
- 00:21:55and you know so if I have to remove so
- 00:21:58so you have to raise the capability of
- 00:22:00AI and make it comprehensive to replace
- 00:22:03or to augment in a way that is uh
- 00:22:06TurnKey so I think until that time
- 00:22:09you'll still have that and people don't
- 00:22:11have the patience to do that you know
- 00:22:13just as we ran the medical Civ Grand
- 00:22:15Challenge for six years we took us a lot
- 00:22:18of effort to cover all the findings in
- 00:22:20chest x-rays lots of clinician
- 00:22:22involvement lots of data sets so such
- 00:22:25resources should be there you know order
- 00:22:27to get to those levels and and that's
- 00:22:29just for one modality and you know so
- 00:22:32you think about that so that's the level
- 00:22:34at which AI should be working if we want
- 00:22:37to have that kind of impact but if
- 00:22:39you're only doing a little bit of this
- 00:22:40or a little bit of that then you'll just
- 00:22:43be a tool that people may want to turn
- 00:22:45you off so then you don't have a way to
- 00:22:48get Revenue yeah it's interesting right
- 00:22:49because the Health Care system is
- 00:22:51already so fragmented that it's a
- 00:22:53reminder to us that if we come in with
- 00:22:55one point solution when I put my
- 00:22:57clinical hat on I'm thinking how does
- 00:22:59that integrate into the Haiku app that
- 00:23:01sits in my pocket so you're right it's
- 00:23:04very hard to think in fact the best
- 00:23:06thing we could do for patients and
- 00:23:08clinicians is to bring down the
- 00:23:09fragmentation there's another debate as
- 00:23:12we were just talking about business
- 00:23:13models and how open or closed do we stay
- 00:23:16with these businesses open source
- 00:23:19becomes there's just a lot you can't
- 00:23:21open up the New York Times The Wall
- 00:23:23Street Journal without seeing major
- 00:23:24companies taking different stances and
- 00:23:26and certainly a lot of the the up and
- 00:23:28coming companies
- 00:23:30um do you mind giving us a little bit of
- 00:23:31your perspective on the role of Open
- 00:23:33Source in the public-private
- 00:23:35Partnerships and actual deployment yeah
- 00:23:38I think open source is extremely
- 00:23:39powerful for you know accelerating
- 00:23:41research and
- 00:23:43um yeah there's a lot of opportunities
- 00:23:45in that in that sector but also
- 00:23:48um the kind of the approach that a lot
- 00:23:50of these open source companies including
- 00:23:52stability uh tend to take is developing
- 00:23:55a kind of General open source models
- 00:23:58that can be publicly released but then
- 00:24:00utilizing their expertise to fine-tune
- 00:24:02these models for specific use cases so I
- 00:24:05think this may also have a potential
- 00:24:07um this is also potentially something
- 00:24:09that can be done in the healthcare
- 00:24:10sector where you can have research
- 00:24:12models that are developed but also
- 00:24:14fine-tuned models for specific clinical
- 00:24:16data sets from hospitals you know
- 00:24:18specific hospitals situations like that
- 00:24:20and I think that will be a really
- 00:24:21interesting model as well
- 00:24:23um for applying AI to healthcare yeah
- 00:24:26excellent any other comments on open
- 00:24:29source so I think that besides what the
- 00:24:33gentleman here said I think the open saw
- 00:24:35is the way to promote
- 00:24:37the demoretization of AI and technology
- 00:24:40so I think as a company like you know
- 00:24:44doing Health Tech we believe in that it
- 00:24:47beside that we also have to look at
- 00:24:50responsible AI responsible software when
- 00:24:53you utilize open source so so like
- 00:24:57example we we have to have a board
- 00:24:59director with the policy make you know
- 00:25:02to make sure that we follow it and we
- 00:25:04make sure they identify data and all the
- 00:25:07validation of the data point that have
- 00:25:09no data leak for you know like personal
- 00:25:12information so that is the fundamental
- 00:25:15when we view our pipeline for for data
- 00:25:18thank you so I'm going to ask one last
- 00:25:21question then we're opening it up and
- 00:25:23then you are the team will keep us on
- 00:25:25time so we've heard a lot this morning
- 00:25:28about what it takes to have a algorithm
- 00:25:31or product but what it really means to
- 00:25:33engage with the regulatory bodies
- 00:25:34whether it's the FDA emea
- 00:25:36it would be helpful to hear some
- 00:25:38practical examples how often are you
- 00:25:40refreshing your algorithms for example
- 00:25:42how have you navigated the quality
- 00:25:45management systems and Regulatory
- 00:25:47environment if we could just have maybe
- 00:25:48one or two examples with that I think it
- 00:25:50brings it home and in fact I think Nishi
- 00:25:54said that that was one of your passions
- 00:25:55the reason why uh you you moved over to
- 00:25:58create the company do you mind just
- 00:26:00getting us started on some of that yeah
- 00:26:02I think when we started the company we
- 00:26:04wanted you know coming from the valley
- 00:26:06the underlying notion was the FDA is the
- 00:26:08reason why AI was not getting into
- 00:26:10clinical practice it was back in 2017
- 00:26:122018 so my co-founder and Ivy flew to DC
- 00:26:15we met with the FDA and they're just
- 00:26:18they're the nicest people they're really
- 00:26:20good at their job it's like and it's
- 00:26:24their job is difficult and they've done
- 00:26:26a tremendous amount of work in making it
- 00:26:28very clear what the expectations are so
- 00:26:30we actually just got FDA clearance for
- 00:26:32the one of Stanford's algorithms this
- 00:26:35was about a month ago and the process
- 00:26:38was was 83 days end to end from
- 00:26:41submission to clearance and what's
- 00:26:43exciting is that we worked with them to
- 00:26:45even come up with okay we are we know
- 00:26:47that we're going to be deploying this
- 00:26:48algorithm it's now live at 200 hospitals
- 00:26:50already and as we deploy this we're
- 00:26:52bound to find cases where like oh yeah I
- 00:26:55think we could come up with improvements
- 00:26:56for the algorithm how do we relay that
- 00:26:58back to the researcher how does the
- 00:27:00researcher work towards you know
- 00:27:02defining the model with that additional
- 00:27:04information and what does that look like
- 00:27:06currently the pros they've actually come
- 00:27:08up with something called pccp which is a
- 00:27:10predetermined Change Control product
- 00:27:11plan and they're really thinking about
- 00:27:13this in the sense of we know that these
- 00:27:15algorithms will need to be trained and
- 00:27:16fine-tuned in the future and how do we
- 00:27:18make it such that it's not too laborious
- 00:27:20to to to to get them cleared again
- 00:27:26right now there seems to be also debate
- 00:27:28on how that standard may change and even
- 00:27:31the boundary of what will be regulated I
- 00:27:33think that's an interesting topic that
- 00:27:35we keep following as well for example
- 00:27:37clinical decision support like the
- 00:27:39sepsis algorithm that was mentioned
- 00:27:41although that's killed right now but can
- 00:27:43that be regulated should that be even
- 00:27:45regulated and I think that's also an
- 00:27:47interesting direction to follow as well
- 00:27:50so one point I want to share is we
- 00:27:52cannot just rely on FDA to really doing
- 00:27:55ethical and responsible because it takes
- 00:27:59a lot of time and a lot of resource so
- 00:28:02the way we view is we you have to
- 00:28:04basically build into the culture and the
- 00:28:07principle of the company where you want
- 00:28:10to ensure that all the data is protected
- 00:28:13by privacy and all of that because
- 00:28:16that's the way to build sustainable
- 00:28:18model for a company you know to go for
- 00:28:21the long term and I think that that's a
- 00:28:24fundamental I mean like FDA you probably
- 00:28:27like I mean for us we have like 52
- 00:28:29comprehensive on just x-ray that people
- 00:28:31say but we cannot like apply like 52
- 00:28:35probably take 10 years for us to or
- 00:28:37maybe more to get on of that so I think
- 00:28:40that we cannot like just rely only on
- 00:28:43that but we and then beside you also
- 00:28:45need to get like ISO and all of those
- 00:28:48equivalent and CE things like that to
- 00:28:51get further but the fundamental is a
- 00:28:54principle and culture it's it's
- 00:28:56interesting a lot of times quality
- 00:28:58Engineers really need to be partnering
- 00:29:01it has to be we had many signs about the
- 00:29:04quality is everyone's uh problem or
- 00:29:07everyone's purpose and we turned it into
- 00:29:09this is everyone's purpose and if you
- 00:29:11create really efficient Quality
- 00:29:12Management Systems regulatory schema it
- 00:29:14actually can be a business accelerant
- 00:29:16and so one of my personal when I hear oh
- 00:29:18they're all these barriers I say as you
- 00:29:20said there's a reason that there are
- 00:29:22systems in place to protect patients we
- 00:29:24just need to help evolve them and I
- 00:29:26think if anyone's looking for
- 00:29:27interesting jobs I think at the
- 00:29:29interface of the private public and
- 00:29:32Regulatory boundary whether it's with AI
- 00:29:35whether it's with now cell and
- 00:29:37gene-based therapies just a little plug
- 00:29:39for I think that's an interesting career
- 00:29:41to choose all right so we're opening it
- 00:29:44up on the regulatory aspects I think you
- 00:29:47hinted on this summer as well but one of
- 00:29:50the biggest barriers to scaling AI for
- 00:29:52broader list of findings is you know
- 00:29:54having to do this verification for one
- 00:29:57finding at a time and the conducting the
- 00:29:59clinical studies for those so that's why
- 00:30:01most people go for a few findings and so
- 00:30:04on but if you want to make the change
- 00:30:06and get greater adoption and and scale
- 00:30:09out we need to change the process of
- 00:30:12evaluations the for such large when you
- 00:30:15have large number of findings to be
- 00:30:17evaluated that was one of the barriers
- 00:30:19we found when we had the technology but
- 00:30:21the company would not go through the
- 00:30:24regulatory approvals for all of these at
- 00:30:27a time because they're just too much
- 00:30:31paperwork and stuff to go through even
- 00:30:34if you had the capability right so I
- 00:30:36think that there needs to be some
- 00:30:38improvements I know FDA is working on it
- 00:30:39obviously the other aspect that I think
- 00:30:42people have emphasized more and where we
- 00:30:43have made a bit more headways in the
- 00:30:45generalization capabilities when you go
- 00:30:47to new deployments and how to update
- 00:30:49your models and so on there you have I
- 00:30:51think a bunch of Radiologists helped
- 00:30:53shape that thinking there but when it
- 00:30:56comes to large scale findings and
- 00:30:58coverage of an entire Anatomy or
- 00:31:02modality and so on we don't have yet you
- 00:31:06know policies that would
- 00:31:08you know ratify such software
- 00:31:11this one all right any live questions
- 00:31:17the panels have been exceedingly clear
- 00:31:19and we do realize that we're standing
- 00:31:20between us and lunch but uh any
- 00:31:23um any questions here
- 00:31:31oh yeah
- 00:31:32um so I would love to hear your take on
- 00:31:35when you might want to categorize
- 00:31:39clinical decision support versus uh
- 00:31:41clinical operations support and
- 00:31:44what might be the toilet challenges like
- 00:31:47the difference between those
- 00:31:51so I'll take this answer so I think that
- 00:31:53we one we target for
- 00:31:56diagnosis assistant is clinical have
- 00:32:00decision support so we even care about
- 00:32:03like naming the product like we call Dr
- 00:32:05Ray the aid so we intend to say we
- 00:32:09assist we not to replace right and we
- 00:32:12believe in land losses the experiment
- 00:32:14religious use AI will replace there is
- 00:32:18just hold on so I guess that's uh one
- 00:32:21and then the second dimension we're
- 00:32:23talking about like operational where we
- 00:32:25build the Enterprise dimension of how to
- 00:32:29Gathering all the data together on the
- 00:32:32on-prem on private cloud or public Cloud
- 00:32:35depending on the environment and where
- 00:32:37we build analytic tool on top of that so
- 00:32:41that we can prove the operational
- 00:32:42efficiency so that's the way we
- 00:32:45differentiate ourselves from the rest we
- 00:32:48have two dimensions of capability to
- 00:32:51solve the problem and comprehensive is
- 00:32:53the fundamental like I mean if you do
- 00:32:55like say the liver cancer we cannot just
- 00:32:58look at only liver we have to look at
- 00:33:01abdomen the whole area of a city and
- 00:33:04find out what's wrong with that same for
- 00:33:07just actually we cannot look at
- 00:33:08pneumatic we have to look at 52 or
- 00:33:11something like that that's you can do
- 00:33:13with big data
- 00:33:16all right so I'm going to close out with
- 00:33:18a question for Dinesh um
- 00:33:20technically what are you most excited
- 00:33:22about as you look in the next five to
- 00:33:24ten years it's obviously been a huge
- 00:33:26amount of change you've focused your
- 00:33:28career really being on the Forefront of
- 00:33:31the latest Technologies what excites you
- 00:33:33the most
- 00:33:35um yeah I think uh the I'm really
- 00:33:38excited by I think yeah what's most
- 00:33:41exciting is the development of
- 00:33:42multimodal systems now and applying
- 00:33:45multimodal systems to Medical AI I think
- 00:33:47what we've seen so far are very unimodal
- 00:33:50applications where you know you're just
- 00:33:51looking at images you're just looking at
- 00:33:54um you know clinical text or time series
- 00:33:56or whatever so being able I mean of
- 00:33:58course in the actual clinical workflow
- 00:34:00you're trying to integrate all of that
- 00:34:01information together in order to make
- 00:34:03clinical decisions so I'm really
- 00:34:05interested in seeing the development of
- 00:34:07multimodal systems that are able to now
- 00:34:10take in you know various different
- 00:34:11sources of data and you know be able to
- 00:34:14provide
- 00:34:15um support to clinicians by
- 00:34:16incorporating all that information so
- 00:34:18I'm really excited by uh developments in
- 00:34:21that field and also yeah I'm just also
- 00:34:23excited by uh not only I think there's a
- 00:34:25lot of opportunities for medical AI in
- 00:34:29various other settings like developing
- 00:34:31countries and third world countries
- 00:34:32where you know the opportunity duties
- 00:34:35and kind of I think yeah there's a lot
- 00:34:37of opportunities in that that in those
- 00:34:38sectors that are not being explored as
- 00:34:40much and I think that's also a really
- 00:34:41exciting uh area for applying AI to uh
- 00:34:45you know help support the the doctors
- 00:34:48that and you know kind of ease their
- 00:34:49burden in in those areas so yeah
- 00:34:52excellent well thank you to the speakers
- 00:34:53for giving us technical Vision but also
- 00:34:56walking us through the realities on the
- 00:34:57ground whether it's with regulatory or
- 00:34:59the business models and people will be
- 00:35:01around if you want to ask anyone any
- 00:35:03further questions so a big round of
- 00:35:04applause to our speakers here
- AI in healthcare
- medical imaging
- patient outcomes
- regulatory compliance
- business models
- open source
- multimodal systems
- clinical decision support
- technology and life science
- healthcare innovation