BIOLOGY explained in 17 Minutes
概要
TLDRA videó bemutatja a Föld keletkezését és a biológia alapjait, beleértve a sejtek felépítését, a DNS szerepét, a gének öröklődését és a sejtosztódás folyamatát. A prokarióták és eukarióták közötti különbségeket is érinti, valamint a mutációk és a természetes szelekció fogalmát. A baktériumok és vírusok közötti különbségeket is megemlíti, és bemutatja az idegrendszer működését. A videó végén a Brilliant platformot ajánlja, amely interaktív tanulási lehetőségeket kínál.
収穫
- 🌍 A Föld 4,5 milliárd éve keletkezett.
- 🧬 A biológia a kémia álcázott formája.
- 🔬 A prokarióták egyszerű sejtek, az eukarióták bonyolultabbak.
- 📜 A DNS tárolja a genetikai információt.
- ⚛️ A sejtosztódás mitózissal és meiózissal történik.
- 🌱 A természetes szelekció a legjobban alkalmazkodó fajok túlélését jelenti.
- 🔄 A mutációk a DNS szekvenciájában bekövetkező változások.
- 🦠 A baktériumok élő sejtek, a vírusok nem élő organizmusok.
- ⚡ Az idegrendszer elektromos jelek segítségével működik.
- 💡 Az ATP energiaforrás a sejtekben.
タイムライン
- 00:00:00 - 00:17:31
A sejtek osztódása két fő mechanizmuson keresztül történik: mitózis és meiózis. A mitózis során a sejtek azonos másolatokat készítenek, míg a meiózis során a gaméták, azaz a spermiumok és petesejtek keletkeznek. A sejtek életciklusa során a legtöbb időt interfázisban töltik, ahol növekednek és másolják a DNS-t. A sejtek osztódása és a gének öröklődése kulcsszerepet játszik a biológiai sokféleség és az evolúció folyamatában.
マインドマップ
ビデオQ&A
Mi a biológia?
A biológia az élet tanulmányozása, amely valójában a kémia álcázott formája.
Mik a prokarióták és eukarióták?
A prokarióták egyszerű sejtek, míg az eukarióták bonyolultabb sejtek, amelyek sejtorganellumokat tartalmaznak.
Mi a DNS szerepe?
A DNS tárolja a genetikai információt, amely meghatározza a szervezet jellemzőit.
Hogyan történik a sejtosztódás?
A sejtosztódás mitózissal és meiózissal történik, amelyek különböző célokat szolgálnak.
Mi a természetes szelekció?
A természetes szelekció a legjobban alkalmazkodó fajok túlélését és szaporodását jelenti.
Mik a mutációk?
A mutációk a DNS szekvenciájában bekövetkező változások, amelyek hatással lehetnek a gének működésére.
Mi a különbség a baktériumok és vírusok között?
A baktériumok élő sejtek, míg a vírusok nem élő organizmusok, amelyek csak gazdaszervezetben képesek szaporodni.
Hogyan működik az idegrendszer?
Az idegrendszer elektromos jelek segítségével kommunikál a test különböző részei között.
Mi az ATP szerepe?
Az ATP energiaforrásként működik a sejtekben, lehetővé téve a különböző biokémiai reakciókat.
Mi a riboszóma szerepe?
A riboszómák fehérjék szintéziséért felelősek, a DNS információját használva.
ビデオをもっと見る
- 00:00:00Hi. You’re on a rock, floating in space. Have did we get here?
- 00:00:04Well, about 4.5 billion years ago, the earth was big ball of flaming rocks, constantly
- 00:00:09bombarded by even more rocks from space. Fun fact! Those rocks probably had some water
- 00:00:13inside them, which has now turned into steam. Breaking news! The earth is cooling down. Oh yeah,
- 00:00:19did I mention tha- [it’s raining.] Whoops, everything’s flooded, but hey,
- 00:00:23at least there’s some cool stuff at the bottom, like hydrothermal vents, which are piping hot
- 00:00:26and filled with a bunch of chemicals, that can make some very interesting stuff. Wait a minute,
- 00:00:31what the heck is going on here? [Biology]
- 00:00:36Biology is the study of life, but really, it’s just chemistry in disguise. I mean
- 00:00:41you and I are basically just a big ball of molecules that can make funny sounds.
- 00:00:50Carbohydrates give you quick energy, lipids store long term energy and make membranes, proteins make
- 00:00:55up tissues and nucleic acids make DNA. Also, to make all the chemical reactions possible, living
- 00:01:00beings, have inside of them a bunch of enzymes. They’re special proteins that act as catalysts,
- 00:01:04which just means they help chemical reactions speed up by either breaking down or combining
- 00:01:08one specific thing. For example, lactase breaks down lactose, the sugar found in milk.
- 00:01:14Ok, so enzymes make life possible by speeding up chemical reactions,
- 00:01:17but what even is…life? Scientists don’t really seem to agree, but obviously a cat is different
- 00:01:23from a rock. The cat can produce energy by metabolizing food, it can grow and develop,
- 00:01:28reproduce, and it responds to the environment, whereas the rock does not.
- 00:01:32Also, unlike rocks, every living thing on earth is made of cells, of which there’s
- 00:01:35two main categories: Eukaryotes and prokaryotes. Eukaryotes have fancy organelles which are bound
- 00:01:41by membranes, like the nucleus, inside of which is DNA. Prokaryotes, have none of those organelles,
- 00:01:46and the DNA is just kind of chilling there, like freely floating around.
- 00:01:50This is why Prokaryotes are just single cell organisms like bacteria
- 00:01:53and archea whereas eukaryotes can form complex organisms like protists, fungi,
- 00:01:57plants and animals. These are what’s known as “kingdoms”, which is a taxonomic rank,
- 00:02:01so basically, how we classify different living things and how they’re related to one another.
- 00:02:06Because there are quite a few species of life on this planet, and naming them cat,
- 00:02:09dangerous cat and water cat wouldn’t really be all that helpful, we also give every species
- 00:02:13a unique and unambiguous scientific name consisting of the genus and the species.
- 00:02:17One thing every species has in common is homeostasis, aka,
- 00:02:21keeping certain conditions in check, so ya don’t die. If you feel warm, your body will sweat,
- 00:02:25if you’re cold, your body will shiver. A cell does kind of the same thing just
- 00:02:29that it balances out concentrations of certain chemicals. You see, enzymes for example, only
- 00:02:34work in a very specific environment, let’s say at some specific pH value. If this changes too much,
- 00:02:38the enzymes will denature and won’t work anymore. To counter this, the cell needs to constantly keep
- 00:02:43up this specific pH value, which is controlled by the concentration of acid and base molecules.
- 00:02:48Ok. But like, how does the cell do that? The secret lies in the cell membrane. You see,
- 00:02:54it’s a semipermeable phospholipid bilayer, okay that’s way too many words, all it is,
- 00:02:58is two layers of these funky looking molecules with a polar head and a nonpolar tail.
- 00:03:03This allows small molecules like water and oxygen to slip right through,
- 00:03:06whereas larger particles like ions need special channels that can be opened or closed, which
- 00:03:10gives the cell control of what goes in and out. Naturally, particles move with the gradient,
- 00:03:14so from a place of high concentration to a place of low concentration. Or,
- 00:03:17in the case of water, it can also move to a place of high solute concentration, so for example salt.
- 00:03:22Welcome to Biology Pro Tips Season 1, tip of the day: do not drink too much saltwater.
- 00:03:27There’s a bunch of salt in saltwater, in fact, more salt than inside of a cell,
- 00:03:32which means it will draw water from your cells and dehydrate you. Yeah that’s it have a great day.
- 00:03:38The process of balancing out gradients is known as “diffusion” and happens automatically, but,
- 00:03:42by using a little bit of energy, particles can actively be moved against the gradient.
- 00:03:47The energy comes from Adenosine Triphosphate or ATP. To be exact,
- 00:03:51the highly energetic chemical bonds between the phosphate groups can be broken to obtain energy.
- 00:03:55This is kind of important, as in, every organism and every cell
- 00:03:59needs to make ATP for example, through cellular respiration which happens in the mitochondria:
- 00:04:05Together with oxygen, glucose, so sugar, is turned into water, carbon dioxide and ATP.
- 00:04:10This is nice, but it only works if you already have glucose. Humans are “heterotrophs”. They
- 00:04:14eat food, inside of which is sugar, which is then broken down into glucose.
- 00:04:18Plants on the other hand are “autotrophs”. Simply put, they said “screw food, I’ll just
- 00:04:23make my own glucose by staring at the sun”. You see, plant cells have small organelles called
- 00:04:28“chloroplasts” inside of which is chlorophyll, which absorbs red and blue light but reflects
- 00:04:32green light, which is why most plants look green. The absorbed energy from light is used to split
- 00:04:36water and make a special form of carbon dioxide which can then be turned into glucose and oxygen.
- 00:04:41Okay quick recap, once you have glucose, either from food or photosynthesis, you can do cellular
- 00:04:46respiration, to get energy in the form of ATP. Chemically, ATP is what’s known as a nucleotide.
- 00:04:51It has a phosphate group, a five carbon sugar and a nitrogenous base. You know what else is made of
- 00:04:56nucleotides? Deoxyribonucleic acid, or DNA. It consists of two strands of nucleotides,
- 00:05:01with the sugar and phosphate groups, but the actually important part is the nitrogenous base,
- 00:05:05which comes in four flavours: Adenine, Thymine, Cytosine and Guanine.
- 00:05:09These bases can form base pairs through hydrogen bonds, where Adenine goes with Thymine,
- 00:05:14and Cytosine goes with Guanine. These bonds are what holds the two strands of DNA together.
- 00:05:19Okay, but, how the heck does that store genetic information? I’m glad you ask!
- 00:05:25A “gene” is a section of this DNA that codes for a special trait,
- 00:05:28by carrying a certain sequence of base pairs, which is like a recipe for making a protein.
- 00:05:34Why proteins? Because they’re like really important, they transport molecules,
- 00:05:37act as enzymes and determine the way you look. For example, the difference between brown and
- 00:05:41blue eyes is the amount of a pigment called “melanin” in the cells of the iris. The OCA2
- 00:05:46Gene codes for “P-Protein” which we believe controls the amount of melanin in cells,
- 00:05:50meaning that the proteins made from this gene, could be what determines your eye colour.
- 00:05:54Cool! There’s just one issue: Your DNA and its information is in the nucleus,
- 00:05:59but proteins are made in organelles called the ribosomes. How do we get the
- 00:06:02information from A to B? The answer is RNA. It’s kind of like DNA, just that it’s most
- 00:06:07often a single strand, it uses a ribose instead of deoxyribose and instead of Thymine it uses Uracil,
- 00:06:12which makes it less stable, but that’s besides the point, here’s what RNA actually does:
- 00:06:16Let’s say you want to make the protein coded for by this gene. An enzyme called
- 00:06:20“RNA polymerase” will split the DNA and make a strand of RNA with the complementary bases,
- 00:06:24essentially copying the information from the DNA to the RNA. This is called “transcription”.
- 00:06:29The new strand is called messenger RNA or mRNA, because it carries this
- 00:06:33message out of the nucleus to a ribosome. Remember how I said that a gene is like a
- 00:06:37recipe for a protein? Well, on the mRNA, which carries the same base sequence as that gene,
- 00:06:42every group of three bases, which is called a “codon”, codes for a specific amino acid,
- 00:06:46which are the building blocks for proteins. Welcome to Biology Pro Tips Season 1, if you want
- 00:06:48to decode a sequence of RNA, there is actually a chart for that! Yeah that’s all have a great day.
- 00:06:48These amino acids are carried by special molecules called transfer RNA or tRNA,
- 00:06:53which have a unique anticodon that can only attach to its matching codon on the mRNA.
- 00:06:58The job of the ribosome is to read over codons on the mRNA and attach the matching tRNA molecules,
- 00:07:03which then leave behind their amino acid. As the ribosome moves along the mRNA and attaches more
- 00:07:08tRNA, which happens a couple thousand times, the amino acids combine into a “polypeptide chain”,
- 00:07:13which is just a really long chain of amino acids, that can be bunched up,
- 00:07:17creased, smacked and folded into a protein. Okay, let’s recap: A gene is copied onto mRNA,
- 00:07:23which is then used to build proteins by assembling a chain of amino acids.
- 00:07:26Aka transcription and translation. Hey, this genetics stuff is pretty
- 00:07:34cool, can we learn more? Absolutely. Oh yeah did I mention that you have, like,
- 00:07:40a bunch of DNA? You have about 20000 protein coding genes, each thousands to millions of
- 00:07:45bases long, and that only makes up around 1% of your entire DNA, the rest is just non-coding.
- 00:07:51PLUS, almost every cell in your body contains your entire genetic code, but genes can be turned on or
- 00:07:56off depending on the cell, which is good, because otherwise your brain cells might just start
- 00:08:00making stomach acid, which would not be good. FUN FACT! If you were to stretch out all the
- 00:08:04DNA of just one single cell, it would be about 2 meters long.
- 00:08:08Wait a minute, how does that fit into a microscopic cell? Well, if you were to look inside
- 00:08:13the nucleus, you wouldn’t find the DNA floating around like this or even this, no, you would
- 00:08:17actually find lots of these worm looking things. To be exact, DNA is coiled up around Proteins
- 00:08:22called “Histones”, which are then condensed into strands of Chromatin, which are then coiled up
- 00:08:25even more to make tightly packed units of DNA called “Chromosomes”, which kinda look like
- 00:08:30worms. Different sections on a chromosome carry different genes, and the entire human genome is
- 00:08:34split amongst 23 different chromosomes, although every body cell has 2 copies of every chromosome,
- 00:08:39one from the mother and one from the father. For most chromosomes, the two copies are
- 00:08:43said to be homologous, meaning that they carry the same genes in the same location. However,
- 00:08:48the two versions of a gene can be different, so the mother’s gene could code for brown eyes,
- 00:08:51while the father’s gene codes for blue eyes. These different versions of a gene are called “alleles”.
- 00:08:56For most of your genes, you have 2 alleles, one on each chromosome from either parent. These alleles
- 00:09:01can be dominant or recessive, which determines which of them is expressed. For example,
- 00:09:06brown eye color is a dominant trait, which is shown by an uppercase B, whereas blue
- 00:09:10is recessive, which is shown by a lowercase b. All this means, is that if you have the dominant
- 00:09:14brown allele, you will have brown eyes, no matter what the second allele is. Only when there are
- 00:09:18two recessive alleles will it be expressed. With this knowledge, we can predict the future!
- 00:09:23Let’s look at how this trait is inherited from parents to children:
- 00:09:26Both of these parents have brown eyes, but also have a recessive blue allele in their
- 00:09:29genotype. Every child receives one allele from each parent randomly, so these are the
- 00:09:34possible combinations for the children. Most combinations contain the dominant
- 00:09:37brown allele, so the child will have brown eyes. But, there is a small chance that a child gets
- 00:09:42two recessive alleles and has blue eyes, even though both parents had brown eyes! You see,
- 00:09:47it’s what’s on the inside that counts. Alright, that’s cool, but reality is not always
- 00:09:51so simple. Some genes are not fully dominant, but not fully recessive either, which means that the
- 00:09:55phenotype, so the appearance, appears to mix. Crossing a red and a white snapdragon, where
- 00:10:00red is “dominant” and white is “recessive” gives you a pink phenotype which is somewhere inbetween,
- 00:10:04aka intermediate inheritance. Or, crossing a brown and a white cow where both colours
- 00:10:08are dominant could give you spotted cow, so both phenotypes are expressed equally, aka codominance.
- 00:10:14Hey remember how I said almost all chromosomes are homologous? Well,
- 00:10:17there’s one exception: the sex chromosomes. Females have two big X chromosomes, whereas
- 00:10:22males have one X and one smaller Y chromosome. These are partially homologous at the top,
- 00:10:27but since the Y chromosome is so small, it’s missing genes that are present
- 00:10:30on the lower part of the X chromosome. These genes are called “X-linked genes”.
- 00:10:34If one of these genes is a recessive trait like colour blindness, males are stuck with that trait,
- 00:10:38whereas females probably have another dominant allele, to override it. This
- 00:10:42is why most colourblind people are male. Now, for genes to even be passed on,
- 00:10:45the body has to make new cells which can inherit the genes. There’s two main mechanisms:
- 00:10:49Mitosis, which is how the body makes identical copies of body cells to grow and repair tissues,
- 00:10:54and Meiosis, which is how the body makes gametes, so sperm and egg cells.
- 00:10:58Mitosis starts with a diploid cell, so a cell with two sets of chromosomes. These chromosomes consist
- 00:11:03of one chromatid, which has to be replicated for the new cell. After replication is when
- 00:11:08you see the familiar X shape consisting of two identical sister chromatids. These are
- 00:11:12split into two identical diploid cells, with two sets of chromosomes consisting of one chromatid.
- 00:11:18Meiosis also starts with a diploid cell, but after replication, the chromosomes comingle
- 00:11:22and exchange genetic information in a process called “crossing over”. The cell is then split
- 00:11:27into two non-identical haploid cells. These have one set of chromosomes, but they still
- 00:11:32consist of 2 sister chromatids. These cells split again into 4 genetically different haploid cells,
- 00:11:37where each chromosomes has one chromatid. Meiosis produces haploid cells, so that when two
- 00:11:42gametes combine into a fertilized egg or “zygote”, it again has the correct number of chromosomes.
- 00:11:47This is cool, but, cell division is only a tiny part of a cell’s entire life cycle. Most of its
- 00:11:51time is actually spent in interphase, aka just chilling. All it does here, is grow and replicate
- 00:11:57all of its DNA, so that it actually has enough genetic material and size to divide in M-Phase.
- 00:12:02There’s multiple checkpoints in the cell cycle which are controlled by proteins
- 00:12:04like p53 or cyclin to check if the cell is healthy and ready to reproduce. If a cell
- 00:12:09is not quite right, it’s either fixed or it destroys itself, which is called
- 00:12:14“apoptosis”…or at least, that’s what it should do. Normal cells replicate until there’s no need to,
- 00:12:18but some cells just keep going. This is because they don’t respond correctly to these checkpoints
- 00:12:22and end up replicating out of control and functioning wrong, which is also known as cancer.
- 00:12:27This damaging behaviour is often a result of a gene mutation, which is a change somewhere in the
- 00:12:31base sequence of a gene. This can happen during DNA replication, when a single base is changed,
- 00:12:36left out or inserted into the original sequence. This often changes the protein coded for by that
- 00:12:41gene and let’s just say that change is often not optimal.
- 00:12:44Another type of mutation happens in chromosomes, where entire sections of DNA could be duplicated,
- 00:12:49deleted, flipped around or transferred between chromosomes. The most famous chromosomal mutation
- 00:12:53is probably when the 21st pair of chromosomes has an additional copy, so that there’s 3
- 00:12:58instead of 2. The result? Down syndrome. Mutations might seem like a bad thing,
- 00:13:02but actually, they can also be neutral or even beneficial. For example,
- 00:13:05a species of yellow grasshoppers might mutate and become green, which makes them
- 00:13:08blend in with the grass and get eaten less. Over time, you can expect to see more and
- 00:13:12more green grasshoppers, as their fitness has increased. Not that kind of fitness,
- 00:13:16fitness as in, they can have more offspring, because they get eaten less.
- 00:13:19This is natural selection and the driving factor behind evolution, as the poorly adapted
- 00:13:23species gets selected against and the fittest species, which has adapted to the environment,
- 00:13:27survives and and has the most offspring, passing down the trait that made them survive.
- 00:13:41If you think adaptation is cool, yes, but also it kind of sucks. You see,
- 00:13:45humans can get sick from bacteria or viruses, but nowadays, we have medicine that works. Good!
- 00:13:50However, what if the bacteria mutates and suddenly, the medicine doesn’t work anymore? Well,
- 00:13:54that’s kind of exactly what is happening, aaand we have no clue how to fix it. So, yeah.
- 00:13:59Oh yeah by the way, one thing many people confuse is bacteria and viruses, and NO, they’re not the
- 00:14:03same. Bacteria are prokaryotes, so they consist of a single cell which can reproduce on its own,
- 00:14:08and we treat bacterial infections such as strep throat and tetanus with antibiotics.
- 00:14:12Viruses are not made of cells, in fact, we’re not even sure they’re alive. They
- 00:14:16share some signs of life, but they can only reproduce inside a host, and they don’t grow,
- 00:14:20so it’s not really alive, but it’s not dead either, it’s more of non-living kind of thing.
- 00:14:25Also, you cannot treat viral infections with antibiotics, most of the time you just have to
- 00:14:29chill out and let your immune system do its thing. Now you might think bacteria are a bad thing, but
- 00:14:33actually, you have millions good bacteria inside your gut. The live in symbiosis with you, so you
- 00:14:37give them food, and they help you digest it. Speaking of digestion, your body is made of
- 00:14:41many complex organ systems that work together to make sure you don’t die,
- 00:14:45and I know what you’re thinking. Actually I don’t, but I know how you’re thinking.
- 00:14:49The nervous system, consisting of nerves, which connect to the spinal cord and lead
- 00:14:52to your brain, is made of cells called “neurons” which can conduct electricity
- 00:14:56along this long tube called the “axon”. Anything you see, think and feel, it’s
- 00:15:00all just electrical signals going to your brain, and your brain telling your body how to respond.
- 00:15:04To be exact, the signals are called “action potentials” and happen at the same strength
- 00:15:08and the same speed every time, so the only difference between “hey,
- 00:15:11I’m a little cold” and “OMG I AM ON FIRE” is where it happens and how frequent the signals are.
- 00:15:16When a neuron is just chilling, the axon is more negative on the inside than on the outside,
- 00:15:20because there’s an unbalanced amount ions. This causes an electric potential of about -70mV.
- 00:15:25When there is a stimulus, signalling molecules called neurotransmitters dock onto ion channels on
- 00:15:30the axon and open them, letting the ions flow and changing the electric potential around that area.
- 00:15:34Now, action potentials are all or nothing. A small stimulus won’t really do anything,
- 00:15:38but, if the potential exceeds about -55 mV, boom, action potential.
- 00:15:43Ion channels around the stimulus open and ions rush into the cell.
- 00:15:46This causes the charge distribution in that section of the axon to reverse for a split second,
- 00:15:51which is called “depolarisation”. The ion channels that are next to
- 00:15:54this area are influenced by this and open as well,
- 00:15:56which causes a chain reaction and sends the signal all the way down the axon.
- 00:16:00Some neurons have a myelin sheath made of Schwann cells, which insulate the
- 00:16:03axon and only leave tiny gaps called nodes of ranvier. If there’s a stimulus, the charges
- 00:16:07can “jump” across the nodes which transmits the signal way faster than a normal neuron.
- 00:16:12But either way, at the bottom, the electric signal reaches a terminal button, which connects the
- 00:16:15current neuron to the dendrites of the next. If you zoom in, you’d notice that the two cells don’t
- 00:16:20even touch, there is actually a small gap. This is once again where neurotransmitters come in:
- 00:16:24Once the button is depolarized, tiny packages of neurotransmitters get released, and bind
- 00:16:28to receptors of following dendrite, either blocking it from doing anything or causing
- 00:16:32another action potential, which repeats the cycle. Hmmm. Something in my brain’s telling me that you
- 00:16:37should definitely subscribe, and also, if you want to stimulate your neurons and find out
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- Föld keletkezése
- biológia
- sejtek
- DNS
- gének
- sejtosztódás
- mitózis
- meiózis
- természetes szelekció
- baktériumok és vírusok