00:00:05
On a usual Saturday,
you wouldn't find me here.
00:00:11
And I mean, of course, I don’t give
TEDx Talks every Saturday.
00:00:16
But what I mean is, you probably
wouldn't find me in a museum.
00:00:20
Rather, if you were looking for me,
00:00:22
you'd probably have to go
to the mountains,
00:00:25
and that is because
I absolutely love hiking.
00:00:28
And in addition to just being outside
and being in nature,
00:00:33
what I really like is this feeling
of physical exhaustion,
00:00:36
sort of this satisfaction
you can feel in every single muscle.
00:00:42
And in the evening,
when it's time to go to bed,
00:00:46
I absolutely cherish
this amazing sleepiness
00:00:50
that fills you from head to toe.
00:00:54
Now you might say, "Well, of course
she's tired. She's been hiking all day.
00:00:59
Plus, not to forget about the effects
of supposedly fresh air."
00:01:05
But there is one factor
that most likely outweighs
00:01:09
the effects of fresh air
and perhaps even physical activity,
00:01:14
and that is exposure to natural daylight.
00:01:19
And today, I hope to convince you
that we should all appreciate daylight
00:01:23
as sort of a natural soporific.
00:01:27
And hopefully, by the end of the talk,
00:01:29
you will also recognize
that we should all pay more attention
00:01:33
to our daily light diet.
00:01:36
But let's start with the question
why daylight is so important
00:01:40
for our organism, for health
and, eventually, for sleep.
00:01:46
Now throughout your body,
in each and every single cell,
00:01:50
there is a tiny molecular clock
ticking inside it.
00:01:54
And to keep these millions
of clocks in sync,
00:01:58
we have one central body clock
that is located in the brain,
00:02:02
in an area which we call the hypothalamus.
00:02:06
And like the conductor of an orchestra,
00:02:08
it communicates the time of day
to each of these molecular clocks.
00:02:14
And this way, it is able
to regulate bodily processes
00:02:18
in sync with the time of day.
00:02:21
For example,
00:02:22
it causes your body temperature
to increase in the morning
00:02:26
and to decrease in the evening.
00:02:28
It choreographs the release
of certain hormones at appropriate times.
00:02:33
And in the evening,
when it’s time to go to bed,
00:02:36
it will also make you tired and sleepy.
00:02:40
But given this precise synchronization
between internal or biological time
00:02:46
and external time or environmental time,
00:02:51
it seems clear that the body clock
00:02:53
cannot be blind or isolated
or shut off from the environment,
00:02:59
but rather, it needs to receive
information about the time of day
00:03:03
from the environment
00:03:04
for it to synchronize with sun time.
00:03:09
And this is achieved by close connections
00:03:12
between the internal biological clock
in the brain and our eyes.
00:03:17
And now you may know
that in the human retina,
00:03:20
there are different types of receptors,
00:03:23
so photoreceptors,
so receptors that sense light.
00:03:28
And classically, we distinguish two types,
the rods and the cones.
00:03:34
Now the rods only contribute
to a visual impression
00:03:38
under very dim lighting conditions.
00:03:41
And here, in the background,
you now see a picture
00:03:45
that might, more or less, be brought about
by only the involvement of the rods.
00:03:51
And what you can see
is that it's only shades of gray,
00:03:54
it's slightly blurred,
00:03:56
and around the point of fixation,
which is indicated by the gray dot here,
00:04:01
you have a little scotoma,
00:04:03
so an area where you can't
really see anything.
00:04:06
Now who recognizes what that is?
00:04:08
Yeah, excellent.
00:04:10
But it's going to be way easier,
00:04:12
and the majority of you
will recognize what it is,
00:04:14
when I now switch to the next slide,
00:04:16
which is brought about
by the involvement of the cones.
00:04:20
Of course, it's the town hall of Basel,
but now you can appreciate the colors,
00:04:27
fine details.
00:04:29
And if this was animated,
you'd even see fine details in motion.
00:04:34
But this is not the whole story,
because only fairly recently,
00:04:38
only in the early 2000s,
another type of cell has been discovered,
00:04:43
and we call them retinal ganglion cells.
00:04:47
Now, you might ask yourselves,
"What picture is she going to show next?"
00:04:53
But I'll have to disappoint you ...
00:04:57
I’m not, and I actually can’t,
show another picture.
00:05:00
Because from all we know,
00:05:02
these cells do not contribute
to a visual impression.
00:05:07
But they are exclusively designed
00:05:10
to sense short wavelength
proportions in daylight.
00:05:15
Sometimes, we also call this blue light.
00:05:19
So they're designed to extract important
information about the time of day
00:05:23
from the environment
00:05:25
and pass this on
to the internal biological clock
00:05:28
in the brain.
00:05:29
And I guess you've all experienced
how well this biological timing system,
00:05:35
this connection between our biological
clock and the external world, or our eyes,
00:05:41
works when we, for example,
travel across time zones.
00:05:46
Now how much light do we actually need?
00:05:50
How much light is enough
for the positive effects on, for instance,
00:05:55
sleep to occur?
00:05:57
And I have to admit,
this is not so easy to answer.
00:06:01
But I think what we have
to keep in keep in mind
00:06:04
is that the biological timing system
has evolved under the open sky
00:06:08
and not in offices or museums.
00:06:13
So it is also optimally tuned
to the conditions we find outside.
00:06:19
Office light or light in rooms
00:06:21
is in no way comparable
to what we find outside.
00:06:26
And therefore,
from a scientific perspective,
00:06:29
I can only recommend you to spend
as much time as you can
00:06:32
under the open sky,
00:06:34
but try to make it at least
30 minutes per day.
00:06:39
Now let's finally talk about sleep.
00:06:42
And I've repeatedly alluded
to the fact that daylight is beneficial
00:06:47
and important for sleep.
00:06:50
And in this context,
I'd like to share a little story.
00:06:54
So last year, I had to go
to hospital for surgery.
00:06:59
And generally, the hospital environment
is a very challenging one for sleep.
00:07:06
Because you spend way too much time
in bed, not moving much.
00:07:10
You might be in pain.
00:07:12
Now and then, someone comes in
to check on you, even during the night.
00:07:16
And if you're as lucky as I was,
you have a snoring roommate.
00:07:20
(Laughter)
00:07:23
And because you, of course,
don't get a lot of daylight.
00:07:28
And that's why many people,
while they're in hospital,
00:07:31
ask for sleep medication.
00:07:33
But as I consider myself
to be a generally good sleeper,
00:07:37
and also because I know
how these drugs work,
00:07:41
I didn’t want this.
00:07:43
But I knew there was something I could do
to help my body sleep as well as possible,
00:07:49
even in this situation.
00:07:52
And that was to maximize
exposure to daylight.
00:07:57
Because as a sleep scientist,
00:08:00
of course, I know
about the research findings.
00:08:02
I know that the more
daylight that you get,
00:08:06
the more tired you will be in the evening,
00:08:09
the easier it will be
for you to fall asleep
00:08:12
and the better the experienced
sleep quality.
00:08:15
And in addition,
00:08:16
daylight exposure has also been shown
to increase proportions of deep sleep,
00:08:21
which again has been linked
to processes of tissue repair,
00:08:26
something not to be
underestimated after surgery.
00:08:30
And beyond the effects on sleep,
00:08:32
we know that patients in brighter rooms
experience less pain and less stress.
00:08:38
And also the effects of daylight
on mood are well established.
00:08:44
So I thought it might be time for me
to put into practice what I often preach.
00:08:48
And I have to confess that usually
00:08:50
I'm much better at giving advice
than following it myself.
00:08:55
But here's what I did.
00:08:57
So first, when it became free,
00:09:00
I asked the nurses to move
my bed to the window place,
00:09:03
because that does not only give you
power of the fresh air supply,
00:09:07
which is highly recommended
in the hospital,
00:09:10
but it also maximizes daylight exposure
even though you're inside.
00:09:15
Second, as soon as I could
leave my bed again,
00:09:18
I went to the park for short walks.
00:09:21
And last, every meal I had,
I tried to take on the little balcony.
00:09:27
Did it work?
00:09:30
Well, it's a bit difficult to say,
00:09:32
because it of course
was a single-case study.
00:09:36
But from patients suffering from insomnia,
00:09:38
so one of the most common sleep disorders,
00:09:42
we know that light therapy is beneficial.
00:09:46
And therefore, I would like
to encourage all of you,
00:09:48
and perhaps especially those
who might belong
00:09:52
to the 25 percent
suffering from sleep problems,
00:09:56
to start your own single-case study.
00:09:59
Thank you.
00:10:01
(Applause)