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foreign
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clinical Excellence meets excellent
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results
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today we're going to talk about NAC or n
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acetylcysteine is a very potent
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antioxidant as well as a
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anti-inflammatory so we're going to
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discuss some of the foods the benefits
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of taking it what can it affect and some
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of the dosages that you can take to
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benefit from taking NAC
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so the food sources are onions and
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garlic
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NAC
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will go and convert to El cysteine and
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with some sulfur containing foods it
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will convert in the liver and make
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glutathione
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now glutathione is a very important
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antioxidant right it's one of the most
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potent ones that our body can produce
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so the benefits are that it helps the
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detoxification Pathways right improves
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insulin sensitivity or insulin
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resistance or diabetes right so it helps
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blood sugar management
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also it's an anti-inflammatory it
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affects cytokines so things like tumor
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necrosis Factor
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interleukins or NF Kappa B it helps
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balance your immune system right so
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oftentimes we give patients glutathione
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for people who have autoimmune processes
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to help calm the inflammatory process
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and help calm the immune system
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the other one we talked about was PCOS
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and that relates to the insulin
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sensitivity right
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brain it affects dopamine centers as
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well as excitatory centers for glutamate
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right
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dopamine is basically the pleasure
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neurotransmitter so if you can affect
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dopamine it will help with addiction
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bipolar disease depression OCD as well
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as anxiety and there are quite a number
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of studies on this how NAC can benefit
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patients who have OCD and the anxiety
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level that comes with it
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glutamate
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the benefits of glutamate for some
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patients is that it will prevent or slow
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down Alzheimer's as well as Parkinson's
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disease over here okay
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another thing is it helps to thin out
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mucus in the lungs so if you have
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pneumonia or if you have
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um
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pulmonary obstructive disease right it
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can help thin the mucus and help the
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breathing aspect of these diseases
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as a matter of fact in the 1963 it was
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classified as a drug and they used it
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for lung disease right and they still
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use it for acetaminophen overdose or
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Tylenol overdose because it can
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significantly impact the liver so they
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use NAC as a drug basically
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now recently they've had issues with the
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FDA and Amazon basically removed all NAC
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Products off their site
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however it is still commercially
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available and can be bought through
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nutrition stores and nutrition shops
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okay
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so
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about dosages
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when we look at NAC
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you can take anywhere between 600 to
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1800 milligrams a day in divided doses
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is best taken on an empty stomach
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however if you get things like nausea or
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loose stool then you might want to take
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it after your meal okay
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things that will enhance an AC is things
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like selenium
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cordyceps
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and go to Cola
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so with these combined nutrients with
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NAC you can basically help to recycle
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glutathione and improve your antioxidant
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levels and improve overall health right
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because when you have a lot of oxidation
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and stress to our body what happens is
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tissues break down
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every cell in your body will take an
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oxidative blow and glutathione is what
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that protective shield is it helps you
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protect against oxidation as well as the
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inflammatory process so NSC is a very
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important nutrient for a lot of
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different patients
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so with respect to let's say covid and
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you have lung issues or breathing issues
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or mucus in your lungs and a NAC can be
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of benefit for those patients
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who have a lot of lung and mucus built
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up within within the lung structures
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right obviously they use things like
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prone positioning to help release some
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of the mucus but as well as NAC being
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utilized it would be the added benefit
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okay
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today we're going to talk about Knack or
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an acetylcysteine
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last week's video generated a lot of
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questions about how glutathione will
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work and what is the mechanisms and what
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are some of the supplements you can take
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to improve glutathione levels so let's
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go into it so the main purpose of taking
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Knack or endocetylcysteine is to improve
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glutathione levels
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glutathione is a tripeptide so it's made
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up of three amino acids glycine
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l-glutamic acid and l-cysteine right so
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NAC or endocetylcysteine will convert to
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l-cysteine and help convert into
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glutathione
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so one of the most important thing is
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that you have to understand is
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it's one of the most potent antioxidants
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that our body can produce right so it
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reduces the effects of what we call
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reactive oxygen species
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right so reactive oxygen species Ros
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that means is that
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our body is under constant stress right
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oxidative stress
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so what happens with reactive oxygen
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species right it's produced in the
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mitochondria right and if it's produced
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it starts to damage some of the
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structures
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as well as the pathways right in order
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to produce energy
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and that damage will cause inflammation
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and inflammation in turn will produce
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more reactive oxygen species
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so this kind of a vicious cycle that can
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occur when we have oxygen reactive
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oxygen species so glutathione is a very
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important antioxidant to help recycle
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some of the glutathione as well as
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improving or reducing the oxidative
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effects okay
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so what we know oral administration of
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glutathione gsh right
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it does not adequately restore
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glutathione right if you take orally
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glutathione it doesn't restore
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glutathione to an adequate level
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it rapidly breaks down uh in our body by
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the liver and the intestines right so
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the glutathione is broken down before it
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can be ever utilized if you take it
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orally
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it does not cross the cell membrane so
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glutathione needs to be kind of taken
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apart going to the cell and rebuilt so
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it will not cross as a whole structure
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and also in some studies glutathione the
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half-life of it is only about 90 minutes
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so it's short-lived
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so the question is how do we improve
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that right
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you also have to know that glutathione
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will decrease as we age so the older you
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get the glute ion stores will go down
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creating more reactive oxygen species
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more inflammation and basically aging
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right
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so let's go ahead and look at some of
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the supplements that we can take
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but before we even do supplements what
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kind of foods can we eat right to help
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improve glutathione levels so you want
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to increase sulfur containing foods
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right onion garlic broccoli kale
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now I know whey protein can also improve
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glutathione levels and certain weeds
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however for most patients that we treat
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in our office
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they have some sort of autoimmune
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condition so whey protein or milk
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protein and wheat is really a No-No in
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our office so if you want to go after
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sulfur-containing Foods I would suggest
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going with these okay it's very
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important to improve sulfur containing
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foods the other one is exercise exercise
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in itself will improve glutathione
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levels right
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and thirdly is coffee enemas now coffee
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enemas are
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known to help with cancer treatments
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right the Gerson Therapy and so forth
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however does it improve glutathione
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levels now that's questionable right
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there are some studies they say that you
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know taking oral caffeine as well as
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coffee enemas really don't improve
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glutathione levels however coffee does
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have a lot of antioxidants so there are
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some benefits of drinking coffee however
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in terms of actually improving
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glutathione levels it's questionable
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right so you can give it a try but there
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are other ways that you can improve
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glutathione levels at this point right
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one of the supplements that you can take
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is s acetyl-l glutathione right
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basically what they did was they
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attached an acetyl group to the
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glutathione
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and then it helps to protect the
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glutathione as it passes through the gut
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or the stomach and it also helps improve
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cell membrane transmission or transport
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so an acetyl group attached to the
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glutathione will help preserve the
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glutathione and get it to the cells that
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need it
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another way is to do liposomal
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glutathione and the way they do that is
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they bind glutathione to
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phospholipids so if you add it to a
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phospholip lipid it can kind of protect
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the glutathione so it can get absorbed
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in the gut as well as through the cell
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membrane right so it has that effect so
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you can do it s acetyl glutathione and a
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liposomal glutathione okay now there are
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other precursors that you can take to
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help enhance what we call recycling of
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the glutathione because glutathione is
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produced in our body but if you have
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some raw materials that help build
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glutathione or recycle glutathione it
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can be quite beneficial and quite
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powerful in terms of health benefits
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so some of the precursors or what we
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call regenerators right recycling
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glutathione
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is selenium okay and then alpha lipoic
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acid
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and Knack which is an acetylcysteine
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cordyceps extracts
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go to Cola extracts
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milk thistle extracts
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and L-glutamine so if you took this on
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let's say an empty stomach
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and you followed it with let's say an
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omega-3 or an EPA DHA fish oil you can
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enhance the absorption of glutathione
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into our system having a more profound
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effect
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now there are many companies that make
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you know combination packets of this
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right I'll list some of the supplements
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that we use in our office Below in the
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description so you want to go ahead and
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read through that but there are a couple
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of different delivery methods that we
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use one is the
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um oral glutathione where we do s
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acetyl-l-glutathione and
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liposopylchonathione
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but we will also use a combination of
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these
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to enhance the recycling properties so
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you can take two different types of
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glutathione support
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and third way that we can also improve
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glutathione is through transdermal
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transmission so if you took a cream that
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has glutathione in it and some cofactors
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and you apply it to the specific area
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that you want to treat
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so let's say we have someone who's got
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Hashimoto's thyroiditis or inflammation
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of the thyroid you can take a
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glutathione cream and apply it to the
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neck and that will help reduce the
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inflammatory process as well as
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reduce maybe TPO and TG antibodies in
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our body so it's very important to do
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combination therapies for some patients
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or some people will be on a maintenance
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dose and all they need is some recycling
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nutrients like this
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right but in our patient population
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where they come in pretty sick we may
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load them up on glutathione in three
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different ways to help improve that so
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it's very important to understand the
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mechanisms and understand how we can
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take it to improve glutathione levels in
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our body all right
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today we're going to talk about the
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different delivery methods for NAC or n
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acetylcysteine and glutathione
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before I get started on the delivery
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methods let's just recap what NAC is and
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what glutathione is and the benefits and
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so forth
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I've made videos on this topic before so
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I'll go ahead and Link the video below
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so you can watch those videos and get a
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little bit more in-depth view of what
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NAC and glutathione is so let's get
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right into it
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an AC delivery method okay food sources
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first so NAC
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or an acetylcysteine you can get from
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cruciferous vegetables garlic onions
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meat fish chicken turkey eggs and whey
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protein basically it's prevalent in
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animal products and garlic and onions
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and cruciferous vegetables
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[Music]
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exercise also will increase glutathione
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and because glutathione is so important
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for reducing what we call Ros or
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reactive oxygen species
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benefits of NAC and glutathione improves
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detox improves insulin resistance PCOS
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or polycystic ovarian syndrome important
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for brain because it helps dopamine and
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glutamate
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it's important for things like addiction
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problems bipolar OCD obsessive
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compulsive disorders depression and
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anxiety also it's very important for
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anti-inflammatory effects so it dampens
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inflammation by impacting some of the
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cytokines
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helps to thin out the mucus of the lungs
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so if you have lung infection or cough
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it can help definitely clear out some of
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that in the lungs
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now in 1963
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glutathione or NAC was classified as a
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drug okay and they used the four lung
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problems right chronic lung issues and
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they also used it for acetaminophen
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overdose
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they still use it to this day
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now enhancers and regenerators of
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glutathione things that enhance
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glutathione production are things like
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selenium alpha lipoic acid Knack or NAC
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cordyceps gauticula and milk thistle you
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can use also L-glutamine and some fish
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oil to help enhance absorption and
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recycling
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what we say enhancers and regenerators
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glutathione is produced in the liver and
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it can be recycled and improved for
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reuse so basically glutathione is the
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most important antioxidant or most
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powerful antioxidant in our body it
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takes the blow the oxidative stress
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NAC is the precursor to glutathione
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again I'll link those videos below so
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you can watch those and get a better
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understanding of what NAC does and what
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glutathione does okay so let's get into
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delivery methods
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NAC and glutathione
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first of all this oral delivery methods
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you can use I use a product called
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glutathione recycler
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so here's the product okay I don't know
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if you guys can see that but it's called
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glutathione recycler it's made by Apex
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energetics now I don't I am not
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sponsored or I don't get any funding or
00:17:00
anything from these nutritional
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companies I find that if I get funded by
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nutritional companies my opinion might
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skew as to what might be best for my
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patients so it's just a product that I
00:17:13
use I really like it it's called
00:17:16
glutathione recycler from Apex
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energetics this has all the precursors
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for glutathione so all the things that
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we talked about things like the
00:17:26
cordyceps goldacola milk thistle NAC
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it's all in this one little product it
00:17:33
was formulated by Dr corazian or Dr K
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some of you who watch my videos might
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know of him he's very big into the
00:17:41
functional medicine uh teaching World
00:17:43
he's an excellent clinician as well and
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he formulated this okay so this is one
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we can use
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as a precursor for Knack or NAC you want
00:17:56
to use between 600 and 1800 milligrams
00:17:59
per day in divided doses on an empty
00:18:02
stomach is usually best
00:18:03
however
00:18:05
if you miss your dosage go ahead and
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take it after the meal it's better to
00:18:10
take it than not take it at all so there
00:18:13
are ideal time to take supplements but
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not everyone can do those times so if
00:18:18
you miss it and if you can't do it on an
00:18:20
empty stomach just go ahead and take it
00:18:22
after the meal okay so that's one oral
00:18:25
delivery method
00:18:28
the other oral delivery method is I use
00:18:31
a product called tumero active and this
00:18:34
also has
00:18:35
the L glutathione it has
00:18:39
um
00:18:41
acetylchlorathione so it had the the
00:18:43
trisomal has this it has an AC which is
00:18:46
the precursor for producing glutathione
00:18:48
it has liposomal glutathione and S
00:18:52
acetyl-l-chlorophyone all in one
00:18:55
so it's a great delivery method because
00:18:59
glutathione breaks down very easily in
00:19:01
the gut the idea is to use different
00:19:04
forms of it to bypass the gut and get it
00:19:07
absorbed better in the GI tract so
00:19:11
that's why they came up these
00:19:12
formulations where they use liposomal
00:19:14
and an acetylated version of it so these
00:19:18
are the two products I would use in my
00:19:20
office
00:19:21
that helps with glutathione and
00:19:24
chlorothiaone recycling okay
00:19:27
now
00:19:28
number one number two is called
00:19:31
transdermal we use a product it's a
00:19:34
cream called oxycell and what you do is
00:19:38
with this cream you can apply it to the
00:19:40
skin it has a great local
00:19:43
anti-inflammatory effect as well as
00:19:46
antioxidant effects so you'll apply like
00:19:49
a small amount of this cream so let's
00:19:51
say you have a thyroid issue you have
00:19:53
Hashimoto's thyroiditis and inflammatory
00:19:55
process of the thyroid or autoimmune
00:19:57
process
00:19:58
you can apply a little bit of that
00:20:00
glutathione cream right into the area
00:20:03
that you want to infect uh effect and
00:20:07
dampen the inflammation in that local
00:20:10
area so transdermally you can use it in
00:20:13
soft areas any vascular areas or areas
00:20:17
that you want to Target so we have a
00:20:19
product called oxycell
00:20:21
we can also use a suppository for
00:20:24
glutathione
00:20:26
so this is a product that we can use
00:20:28
it's called xenaplex and this this is a
00:20:32
suppository and in that suppository it
00:20:34
has organic coffee extract and
00:20:36
glutathione
00:20:37
so after uh having a normal bowel
00:20:40
movement or evacuating your bowels you
00:20:43
can do a suppository to help uh boost
00:20:47
glutathione and bypassing the gut okay
00:20:50
so that's another delivery method
00:20:53
the final delivery method is nebulizing
00:20:56
glutathione I use a product called
00:20:58
l-glutathione Plus
00:21:00
right there
00:21:02
and it's from a company called Vera
00:21:05
Naturals and I'll like to link the
00:21:07
product below for you
00:21:10
okay and what you do is you open up one
00:21:12
of the capsules
00:21:14
so you take a glutathione capsule like
00:21:16
this
00:21:18
like this product right here
00:21:20
and you get a nebulizer and this is just
00:21:23
the apparatus I would use for the
00:21:26
nebulizing portion of it so you open up
00:21:29
a capsule
00:21:30
and let's say you drop it in here you
00:21:32
open the capsule throw it in there right
00:21:33
you can use a little bit of saline
00:21:36
solution that you can use for like nasal
00:21:38
rinses or you can use distilled water
00:21:41
and you put a little bit in here
00:21:43
and you close it up
00:21:46
you'll use a little nebulizing machine
00:21:48
that you attach to the bottom of this
00:21:50
and you take it and you breathe it in
00:21:54
now there are different ways to do this
00:21:56
with different machines out there you
00:21:57
can use kind of something to mystify or
00:22:00
Mist uh the the product and you
00:22:04
basically can gently breathe it in right
00:22:06
if you have a lot of sinus problems you
00:22:08
breathe in through the nose out through
00:22:10
the mouth if you have lung problems you
00:22:12
want to breathe in deeply and get it
00:22:14
into the lungs a bit so you can use
00:22:16
glutathione to help in multiple ways it
00:22:20
has multiple delivery methods that you
00:22:23
can utilize and when you're sick you can
00:22:26
use probably all of the delivery methods
00:22:29
to really boost your glutathione levels
00:22:31
and to recover from health issues so
00:22:37
those are great different methods I'll
00:22:38
go ahead and Link the products below
00:22:40
also unfortunately unfortunately some of
00:22:43
the products are prescription only from
00:22:46
a physician so you have to find the
00:22:47
physician who's willing to prescribe it
00:22:49
for you but I'll try to link equivalent
00:22:52
products there for you
00:22:54
um in the link below all right my name
00:22:56
is Dr Jin sung we're a clinical
00:22:58
Excellence meets excellent results and
00:23:01
we'll see you guys next week on the
00:23:03
healthy side have an awesome day
