A simple solution to treat your fatty liver | James Joseph | TEDxGateway

00:08:20
https://www.youtube.com/watch?v=bSsZYhXLE6Y

Summary

TLDRThe speaker addressed the pressing issue of diabetes and fatty liver in India, highlighting startling statistics such as 101 million diabetic individuals and 136 million pre-diabetic among the populace. He stressed that treating diabetes without addressing fatty liver is ineffective, as fatty liver is a precursor and affects 1 in 3 Indians. The speaker invented jackfruit flour as a solution, emphasizing its benefits for diabetes and fatty liver through clinical trials and studies. The flour, rich in soluble fiber, can effectively reduce blood sugar and reverse fatty liver when incorporated into the diet. Chance encounters with leaders like Doctor Kalam inspired this journey. The speaker advocates fortifying wheat flour with 10% jackfruit flour, proposing a scalable solution for India, given the large supply of jackfruits.

Takeaways

  • ๐Ÿ Fatty liver is a precursor to diabetes, affecting 1 in 3 people in India.
  • ๐Ÿž Jackfruit flour can lower blood sugar and reverse fatty liver.
  • ๐Ÿ“Š Studies showed adding jackfruit flour reduces liver fat in just three months.
  • ๐Ÿ‡ฎ๐Ÿ‡ณ India has 2.5 billion jackfruits, making this solution widely available.
  • ๐Ÿฅ„ Just a tablespoon of jackfruit flour can make a significant health difference.
  • ๐Ÿ“š Clinical trials and studies back the health benefits of jackfruit flour.
  • ๐Ÿ‘จโ€โš•๏ธ Doctor Kalam encouraged integrating jackfruit into Indian diets.
  • ๐Ÿฉบ Health benefits include preventing obesity and reducing fatty liver markers.
  • ๐ŸŒพ Fortifying wheat with jackfruit flour can be a scalable solution.
  • ๐Ÿ”ฌ Soluble fiber in jackfruit flour prevents sugar and fat from reaching the liver.

Timeline

  • 00:00:00 - 00:08:20

    The speaker introduces a personal story about transitioning from a notable software company to addressing diabetes and fatty liver issues in India, particularly using the jackfruit. They highlight the alarming statistics of diabetes and pre-diabetes in India, noting that treating diabetes requires addressing fatty liver problems. The introduction sets the stage for the speaker's journey and innovations inspired by meeting with Doctor Kalam, leading to a potential dietary solution using jackfruit.

Mind Map

Video Q&A

  • What is the speaker's main message?

    Promoting jackfruit flour as a solution to diabetes and fatty liver.

  • How many people in India are diabetic or pre-diabetic?

    101 million are diabetic and 136 million are pre-diabetic.

  • Why is fatty liver a significant problem?

    Fatty liver affects 1 in 3 Indians and is a precursor to diabetes.

  • What is the significance of jackfruit flour?

    It can reduce blood sugar and reverse fatty liver when added to diets.

  • How effective was jackfruit flour in the studies mentioned?

    It reduced fatty liver markers in 50% of diabetes patients within three months.

  • What prompted the speaker's research into jackfruit?

    A suggestion from Doctor Kalam to incorporate it into Indian diets.

  • What are the benefits of the soluble fiber in jackfruit flour?

    Prevents fat, sugar, and cholesterol from reaching the liver.

  • How scalable is the solution proposed?

    India has 2.5 billion jackfruits, making it widely available.

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  • 00:00:00
    Transcriber: Joao Victor Coelho Reviewer: Ines Dif
  • 00:00:08
    My story is about leaving the biggest software company to serve
  • 00:00:13
    the biggest fruit to a billion people. 365 days to control diabetes.
  • 00:00:23
    101 million people in India are diabetic. But that's not the problem.
  • 00:00:29
    136 million people in India are pre-diabetic.
  • 00:00:33
    18% of our largest state, Uttar Pradesh, is pre-diabetic.
  • 00:00:40
    And if we don't do anything in four years,
  • 00:00:44
    they will all become diabetic and India will overtake China in diabetes.
  • 00:00:49
    Even that is not the problem.
  • 00:00:52
    The real problem is 1 in 3 people in India, including children,
  • 00:00:58
    have fatty liver from food.
  • 00:01:02
    Friends, The sad truth is
  • 00:01:05
    we can not fix diabetes without fixing fatty liver
  • 00:01:11
    For the whole family, including children. You know why?
  • 00:01:15
    Before the excess food gets stored
  • 00:01:19
    as fat in this tiny pancreas causing diabetes,
  • 00:01:26
    a lot of fat gets stored in the biggest organ inside our body, the liver.
  • 00:01:33
    So treating diabetes without treating fatty liver is like
  • 00:01:39
    e mopping the floor without turning the tap off.
  • 00:01:43
    But what has fatty liver got to do with the jackfruit,
  • 00:01:49
    which is not even a fruit till the last two days?
  • 00:01:53
    Till then, it is consumed as a green vegetable.
  • 00:01:57
    In 2014, I wrote a book about coming back to India and working
  • 00:02:03
    for Microsoft from my village in Kerala,
  • 00:02:06
    and the publisher sent the first copy to Doctor Kalam and towards the end of
  • 00:02:12
    the book, Doctor Kalam spotted that I have found a treasure in
  • 00:02:17
    the Jackfruits in my backyard and he called me for a meeting and during
  • 00:02:22
    the meeting I told him about a discovery.
  • 00:02:26
    The Kerala tradition of consuming the green jackfruit as
  • 00:02:30
    a meal is better than roti for diabetes.
  • 00:02:34
    Convinced by the nutritional advantage,
  • 00:02:37
    Doctor Kalam asked me to find an easy way to add
  • 00:02:41
    the green jackfruit to roti to reduce wheat than replacing roti itself.
  • 00:02:46
    Inspired by that ask, I invented a flour from the green jackfruit using
  • 00:02:55
    the soluble fibre of the jackfruit itself as a binder,
  • 00:03:00
    and I put it through a clinical trial to confirm adding one tablespoon of
  • 00:03:05
    jackfruit flour in our Breakfast,
  • 00:03:07
    lunch and dinner with roti can reduce average blood sugar level in just 90 days.
  • 00:03:20
    And I presented the evidence at
  • 00:03:22
    the American Diabetes Association's conference and even published that in
  • 00:03:25
    the Nature journal. And that prompted a lot of people to start using
  • 00:03:32
    the jackfruit flour in their roti.
  • 00:03:34
    And we started hearing cases after cases of reversing fatty liver.
  • 00:03:40
    And the turning point was a call from Doctor Abichandani from Ahmedabad.
  • 00:03:46
    James, we started using the jackfruit flour
  • 00:03:50
    and my wife not only reduced her blood sugar level,
  • 00:03:53
    but she reversed a grade two fatty liver to grade one in just three months.
  • 00:03:58
    James, this is bigger than diabetes. And that led to two separate studies.
  • 00:04:06
    The first one a preclinical study On mice by Doctor Divya Kumar,
  • 00:04:13
    an expert researcher on fatty liver at J.s.s. Medical College, Mysore.
  • 00:04:18
    The study was on the Western diet,
  • 00:04:20
    which is high sugar and high fat compared to the healthy diet,
  • 00:04:24
    more like a high fat burger with a large glass of cola which is full of sugar.
  • 00:04:29
    And as you can see in the graph the first 12 weeks,
  • 00:04:34
    the Western diet significantly increased body weight.
  • 00:04:37
    And in the 12th week we replaced just 5% calorie in
  • 00:04:41
    the Western diet with jackfruit flour and the placebo group with wheat flour.
  • 00:04:45
    And the wheat flour group continued to increase body weight,
  • 00:04:48
    while the green line, the jackfruit flour,
  • 00:04:51
    remained flat and the liver fat was significantly lower.
  • 00:04:55
    It completely prevented obesity and fatty liver,
  • 00:05:01
    and this study revealed two things.
  • 00:05:03
    First, just 5% jackfruit flour in any processed food,
  • 00:05:09
    from an apple pie to biscuits to a burger patty can prevent obesity
  • 00:05:16
    and fatty liver. Number two the mechanism of action.
  • 00:05:22
    The secret sauce in the jackfruit flour turned out to be the soluble fiber.
  • 00:05:28
    It has 50% more soluble fiber than even oats,
  • 00:05:32
    and has the property to prevent sugar,
  • 00:05:35
    fat and from cholesterol from reaching our liver.
  • 00:05:39
    The second study, a real world clinical trial at Doctor Avicenna Clinic,
  • 00:05:46
    a long term study. He asked
  • 00:05:48
    a group of 30 diabetes patients to start adding jackfruit flour in their roti.
  • 00:05:54
    And in the first three months itself,
  • 00:05:56
    50% half of them reduced their fatty liver markers,
  • 00:06:02
    including cases of grade three to grade two.
  • 00:06:05
    Grade two to grade one and grade one to nil in just three months.
  • 00:06:10
    What does this mean to an average person in Uttar Pradesh,
  • 00:06:14
    who consumes eight kilograms of wheat flour in a month for OT.
  • 00:06:19
    One tablespoon of jackfruit flour is equivalent to just 10% of that wheat
  • 00:06:26
    flour per meal. And the way India iodized salt.
  • 00:06:33
    If we can fortify wheat flour with just 10% jackfruit flour,
  • 00:06:38
    we can reverse fatty liver and prevent diabetes for the whole family,
  • 00:06:43
    including children. And this is a massively scalable and practical idea
  • 00:06:50
    for India. Do you know why? we have 2.5 billion jackfruits in India? 2.5 billion.
  • 00:06:57
    And half a million people in India have already used
  • 00:07:01
    the jackfruit flour in their roti with 90% satisfaction. You know why?
  • 00:07:07
    A two minutes video of me presenting to Prime Minister Modi going viral.
  • 00:07:16
    To close. I have something romantic.
  • 00:07:19
    I come from the only place
  • 00:07:21
    on earth where every tension between couples melts away like butter.
  • 00:07:27
    When one of them says in the carol
  • 00:07:31
    My Dear Lover, or even better, in the carol Carol,
  • 00:07:37
    you are the liver of my liver.
  • 00:07:40
    Our ancestors from the land of Ayurveda knew the liver is bigger
  • 00:07:46
    and more beloved than the sweetheart.
  • 00:07:50
    So every time you see a plate with more roti than vegetables,
  • 00:07:55
    you should say naturally it's going to hurt your liver.
  • 00:07:59
    And if the roti has the jackfruit flower, you should say in the calendar Kerala,
  • 00:08:04
    it's going to melt away the fat in your liver. Thank you.
Tags
  • Diabetes
  • Fatty Liver
  • Jackfruit Flour
  • Nutrition
  • India
  • Clinical Trials
  • Soluble Fiber
  • Health
  • Doctor Kalam
  • Obesity